ES2149193T3 - Compuestos heterociclicos sustituidos con alquilo. - Google Patents

Compuestos heterociclicos sustituidos con alquilo.

Info

Publication number
ES2149193T3
ES2149193T3 ES93610066T ES93610066T ES2149193T3 ES 2149193 T3 ES2149193 T3 ES 2149193T3 ES 93610066 T ES93610066 T ES 93610066T ES 93610066 T ES93610066 T ES 93610066T ES 2149193 T3 ES2149193 T3 ES 2149193T3
Authority
ES
Spain
Prior art keywords
rent
compounds replaced
heterociclic compounds
heterociclic
replaced
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93610066T
Other languages
English (en)
Inventor
Peter Moldt
Jorgen Scheel-Kruger
Leif Helth Jensen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NTG Nordic Transport Group AS
Original Assignee
Neurosearch AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK921541A external-priority patent/DK154192D0/da
Application filed by Neurosearch AS filed Critical Neurosearch AS
Application granted granted Critical
Publication of ES2149193T3 publication Critical patent/ES2149193T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Abstract

LA PRESENTE INVENCION SE REFIERE A COMPUESTOS DE LA FORMULA (I), CUALQUIER MEZCLA DE ESTOS O UNA SAL FARMACEUTICAMENTE ACEPTABLE DE ESTOS, DONDE R, R3, Y R4 TIENEN CADA UNO UN SIGNIFICADO ESTABLECIDO MAS ADELANTE EN LA ESPECIFICACION. LOS COMPUESTOS POSEEN PROPIEDADES FARMACEUTICOS VALORABLES COMO INHIBIDORES DE REACEPTACION DE DOPAMINA.
ES93610066T 1992-12-23 1993-12-20 Compuestos heterociclicos sustituidos con alquilo. Expired - Lifetime ES2149193T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK921541A DK154192D0 (da) 1992-12-23 1992-12-23 Heterocycliske forbindelser
US08/093,183 US5369113A (en) 1992-12-23 1993-07-16 Certain 2,3-diphenyl-2-(1,2,4-oxadiazol-5-yl)tropanes useful as dopamide reuptake inhibitors
US08/093,181 US5444070A (en) 1992-12-23 1993-07-16 Phenyl substituted heterocyclic compounds

Publications (1)

Publication Number Publication Date
ES2149193T3 true ES2149193T3 (es) 2000-11-01

Family

ID=27221329

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93610066T Expired - Lifetime ES2149193T3 (es) 1992-12-23 1993-12-20 Compuestos heterociclicos sustituidos con alquilo.

Country Status (13)

Country Link
EP (1) EP0604355B1 (es)
JP (1) JPH06293759A (es)
AT (1) ATE195314T1 (es)
AU (1) AU671163B2 (es)
CA (1) CA2112061C (es)
DE (1) DE69329184T2 (es)
DK (1) DK0604355T3 (es)
ES (1) ES2149193T3 (es)
FI (1) FI935798A (es)
GR (1) GR3034746T3 (es)
NO (1) NO301164B1 (es)
NZ (1) NZ250513A (es)
PT (1) PT604355E (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6329520B1 (en) * 1990-08-09 2001-12-11 Research Triangle Institute Cocaine receptor binding ligands
AU672644B2 (en) * 1992-12-23 1996-10-10 Neurosearch A/S Aryl substituted heterocyclic compounds
CZ284379B6 (cs) * 1994-04-19 1998-11-11 Neurosearch A/S Tropanové deriváty, způsob jejich přípravy a jejich použití
ATE204872T1 (de) * 1995-03-24 2001-09-15 Neurosearch As Verfahren zur herstellung von anhydroecgonin- estern
JP3238414B2 (ja) * 1996-02-22 2001-12-17 ニューロサーチ・アクティーゼルスカブ トロパン―誘導体、その製造方法及びその使用方法
GB9915617D0 (en) * 1999-07-05 1999-09-01 Knoll Ag Therapeutic agents
WO2003045388A1 (en) 2001-11-30 2003-06-05 Neurosearch A/S Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases
MXPA06003762A (es) 2003-10-16 2006-06-14 Boehringer Ingelheim Int Composicion farmaceutica que comprende un inhibidor de recaptacion de neurotransmisor monoamina y un inhibidor de acetilcolinesterasa.
EP1779851A1 (en) 2005-10-31 2007-05-02 Boehringer Ingelheim Pharma GmbH & Co.KG Treatment of diabetes

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3813404A (en) * 1972-11-15 1974-05-28 Sterling Drug Inc Tropane-2-carboxylates and derivatives
FR2276823A1 (fr) * 1974-07-04 1976-01-30 Roussel Uclaf Nouveaux derives de la dibenzo(b.e)thiepine et leurs sels, procede de preparation et application a titre de medicaments desdits produits
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
IE63906B1 (en) * 1987-11-13 1995-06-14 Novo Nordisk As Azabicyclic compounds and their preparation and use
NZ227684A (en) * 1988-01-30 1991-07-26 Merck Sharp & Dohme Pyrazine, pyridazine, and pyrimidine derivatives and pharmaceutical compositions
EP0398578B1 (en) * 1989-05-17 1997-03-12 Pfizer Inc. 2-piperidino-1-alkanol derivatives as antiischemic agents
DK198590D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
EP0905135B1 (en) * 1991-11-15 2006-09-06 Research Triangle Institute Cocaine receptor binding ligands
US5262428A (en) * 1992-03-13 1993-11-16 Wake Forest University Biologically active tropane derivatives
US5268480A (en) * 1992-09-22 1993-12-07 Mayo Foundation For Medical Education And Research Cocaine analogs

Also Published As

Publication number Publication date
NO301164B1 (no) 1997-09-22
NO934758L (no) 1994-06-24
AU671163B2 (en) 1996-08-15
FI935798A0 (fi) 1993-12-22
ATE195314T1 (de) 2000-08-15
JPH06293759A (ja) 1994-10-21
CA2112061A1 (en) 1994-06-24
FI935798A (fi) 1994-06-24
EP0604355A3 (en) 1995-02-08
DK0604355T3 (da) 2000-12-04
CA2112061C (en) 2002-11-19
DE69329184D1 (de) 2000-09-14
NO934758D0 (no) 1993-12-22
AU5236193A (en) 1994-07-07
GR3034746T3 (en) 2001-02-28
NZ250513A (en) 1996-03-26
EP0604355B1 (en) 2000-08-09
PT604355E (pt) 2001-01-31
EP0604355A2 (en) 1994-06-29
DE69329184T2 (de) 2001-04-05

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