ES2146227T3 - Composiciones farmaceuticas que contienen nifedipina y procedimiento para su preparacion. - Google Patents
Composiciones farmaceuticas que contienen nifedipina y procedimiento para su preparacion.Info
- Publication number
- ES2146227T3 ES2146227T3 ES93901850T ES93901850T ES2146227T3 ES 2146227 T3 ES2146227 T3 ES 2146227T3 ES 93901850 T ES93901850 T ES 93901850T ES 93901850 T ES93901850 T ES 93901850T ES 2146227 T3 ES2146227 T3 ES 2146227T3
- Authority
- ES
- Spain
- Prior art keywords
- pct
- nifedipine
- pharmaceutical compositions
- procedure
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
- Saccharide Compounds (AREA)
Abstract
SE PROPORCIONAN LOS COMPUESTOS Y LOS PROCESOS PARA SU PREPARACION EN LOS QUE LA NIFEDIPINA ESTA ENCUBIERTA SOBRE UN TRANSPORTADOR SOLUBLE EN AGUA EN UNA MEZCLA CON POLIVINILOPIRROLIDON O UN COPOLIMERO DE N Y UN POLIMERO DE BASE ACRILICA ACEPTABLE FARMACEUTICAMENTE. LA RAZON DE POLIVINILOPIRROLIDON O COPOLIMERO N ON / ACETATO DE VINILO AL CONTENIDO DE NIFEDIPINA ESTA EN LA PROPORCION DE ENTRE 1:1 A 1:10 Y LA RAZON DEL POLIMERO DE BASE ACRILICA AL CONTENIDO DE NIFEDIPINA ESTA EN LA PROPORCION DE ENTRE 1:4 A 1:20. SE PROPORCIONAN LOS COMPUESTOS ADECUADOS PARA UNA ADMINISTRACION DE NIFEDIPINA UNA VEZ AL DIA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929200607A GB9200607D0 (en) | 1992-01-13 | 1992-01-13 | Pharmaceutical compositions containing nifedipine and process for the preparation thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2146227T3 true ES2146227T3 (es) | 2000-08-01 |
Family
ID=10708487
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93901850T Expired - Lifetime ES2146227T3 (es) | 1992-01-13 | 1993-01-12 | Composiciones farmaceuticas que contienen nifedipina y procedimiento para su preparacion. |
Country Status (24)
Country | Link |
---|---|
US (1) | US5594013A (es) |
EP (1) | EP0620733B1 (es) |
JP (1) | JPH07503003A (es) |
AT (1) | ATE191144T1 (es) |
AU (1) | AU659529B2 (es) |
CA (1) | CA2126864A1 (es) |
DE (2) | DE4390075T1 (es) |
DK (2) | DK0620733T3 (es) |
ES (1) | ES2146227T3 (es) |
FI (1) | FI943316A (es) |
GB (2) | GB9200607D0 (es) |
HU (2) | HU219338B (es) |
IS (1) | IS1620B (es) |
MY (1) | MY110660A (es) |
NL (1) | NL9320021A (es) |
NO (1) | NO305223B1 (es) |
NZ (1) | NZ246374A (es) |
PH (1) | PH30985A (es) |
PL (1) | PL170935B1 (es) |
PT (1) | PT620733E (es) |
RU (1) | RU2106139C1 (es) |
SE (1) | SE9402457L (es) |
WO (1) | WO1993013773A1 (es) |
ZA (1) | ZA93195B (es) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994005262A1 (en) * | 1992-09-10 | 1994-03-17 | F.H. Faulding & Co. Limited | Sustained release matrix composition |
US5455046A (en) * | 1993-09-09 | 1995-10-03 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems for insoluble drugs |
US5773025A (en) * | 1993-09-09 | 1998-06-30 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems--amorphous drugs |
US5871776A (en) * | 1995-01-31 | 1999-02-16 | Mehta; Atul M. | Controlled-release nifedipine |
EP0952770A4 (en) * | 1995-09-07 | 1999-12-22 | Fuisz Technologies Ltd | SYSTEM FOR MAKING SUBSTANTIALLY NON-SOLUBLE BIOALTERANT AGENTS BIOAVAILABLE |
CO4771151A1 (es) * | 1996-01-19 | 1999-04-30 | Rachitzky Falicman Pablo Alberto | Procedimiento para la elaboracion de una preparacion farmace utica que contiene nifedipina y la preparacion farmaceutica obtenida mediante el mismo |
AU695734B2 (en) * | 1996-07-08 | 1998-08-20 | Penwest Pharmaceuticals Co. | Sustained release matrix for high-dose insoluble drugs |
IT1284604B1 (it) * | 1996-09-27 | 1998-05-21 | Roberto Valducci | Composizioni farmaceutiche a rilascio controllato per somministrazione orale contenenti nifedipina come sostanza attiva |
US5837379A (en) * | 1997-01-31 | 1998-11-17 | Andrx Pharmaceuticals, Inc. | Once daily pharmaceutical tablet having a unitary core |
US5922352A (en) * | 1997-01-31 | 1999-07-13 | Andrx Pharmaceuticals, Inc. | Once daily calcium channel blocker tablet having a delayed release core |
US6056977A (en) | 1997-10-15 | 2000-05-02 | Edward Mendell Co., Inc. | Once-a-day controlled release sulfonylurea formulation |
US6485748B1 (en) | 1997-12-12 | 2002-11-26 | Andrx Pharmaceuticals, Inc. | Once daily pharmaceutical tablet having a unitary core |
US6264872B1 (en) | 1997-12-30 | 2001-07-24 | Kimberly-Clark Worldwide, Inc. | Method of forming thin, embossed, textured barrier films |
US6969529B2 (en) | 2000-09-21 | 2005-11-29 | Elan Pharma International Ltd. | Nanoparticulate compositions comprising copolymers of vinyl pyrrolidone and vinyl acetate as surface stabilizers |
US6706283B1 (en) | 1999-02-10 | 2004-03-16 | Pfizer Inc | Controlled release by extrusion of solid amorphous dispersions of drugs |
US6168806B1 (en) | 1999-03-05 | 2001-01-02 | Fang-Yu Lee | Orally administrable nifedipine pellet and process for the preparation thereof |
JP4541647B2 (ja) * | 2000-11-20 | 2010-09-08 | エラン ファーマ インターナショナル,リミティド | 表面安定剤として共重合体を含むナノ粒子組成物 |
SE0100200D0 (sv) * | 2001-01-24 | 2001-01-24 | Astrazeneca Ab | New film coating |
SK9132003A3 (en) * | 2001-12-19 | 2004-02-03 | Astrazeneca Ab | A film coating composition, a coating film, pharmaceutical formulation comprising same and a process for its production |
US6620900B2 (en) * | 2002-02-07 | 2003-09-16 | Isp Investments Inc. | Proliferous copolymer of vinyl pyrrolidone and vinyl acetate |
MY140561A (en) | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
WO2004026361A1 (en) * | 2002-09-18 | 2004-04-01 | Medtronic Vascular, Inc. | Controllable drug releasing gradient coatings for medical devices |
EP1874274A2 (en) * | 2005-04-06 | 2008-01-09 | Mallinckrodt Inc. | Matrix-based pulse release pharmaceutical formulation |
WO2007106111A2 (en) * | 2005-07-01 | 2007-09-20 | Elan Pharma International Limited | Nanoparticulate and controlled release compositions comprising nilvadipine |
JP5351490B2 (ja) * | 2007-10-25 | 2013-11-27 | バイエル薬品株式会社 | ニフェジピン含有有核錠剤およびその製法 |
RU2629843C1 (ru) * | 2016-05-24 | 2017-09-04 | федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет) | Способ получения мази нифедипина (варианты) |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2400819C2 (de) * | 1974-01-09 | 1982-04-22 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung fester Zubereitungen von schwerlöslichen Arzneimittelwirkstoffen in feinster Verteilung |
GB1579818A (en) * | 1977-06-07 | 1980-11-26 | Yamanouchi Pharma Co Ltd | Nifedipine-containing solid preparation composition |
EP0001247A1 (en) * | 1977-09-14 | 1979-04-04 | Kanebo, Ltd. | Pharmaceutical preparation containing nifedipine and a method for producing the same. |
CA1146866A (en) * | 1979-07-05 | 1983-05-24 | Yamanouchi Pharmaceutical Co. Ltd. | Process for the production of sustained release pharmaceutical composition of solid medical material |
EP0047894B2 (en) * | 1980-09-05 | 1990-09-05 | Argus Chemical Corporation | Homogeneous storage-stable liquid barium-cadmium-triphosphite stabilizer systems for polyvinyl chloride resins |
DE3033919A1 (de) * | 1980-09-09 | 1982-04-22 | Bayer Ag, 5090 Leverkusen | Feste arzneizubereitungen enthaltend nifedipin und verfahren zu ihrer herstellung |
JPS5846019A (ja) * | 1981-09-14 | 1983-03-17 | Kanebo Ltd | 持続性ニフエジピン製剤 |
DE3270785D1 (en) * | 1981-10-29 | 1986-05-28 | Bayer Ag | Process for preparing solid fast-releasing drug formulations of dihydropyridines |
DE3580384D1 (de) * | 1984-04-09 | 1990-12-13 | Toyo Boseki | Praeparat mit verzoegerter freigabe zum aufbringen auf die schleimhaeute der mundhoehle. |
DE3424553A1 (de) * | 1984-07-04 | 1986-01-09 | Bayer Ag, 5090 Leverkusen | Feste arzneizubereitungen mit dihydropyridinen und verfahren zu ihrer herstellung |
IT1178511B (it) * | 1984-09-14 | 1987-09-09 | Pharmatec Spa | Procedimento per la preparazione di una forma solida per uso orale a base di nifedipina con rilascio |
DE3438830A1 (de) * | 1984-10-23 | 1986-04-30 | Rentschler Arzneimittel | Nifedipin enthaltende darreichungsform und verfahren zu ihrer herstellung |
FR2579510B1 (fr) * | 1985-03-29 | 1989-12-15 | Demler Sa Ets | Table vibrante pour la fabrication de produits en beton |
FR2585174B1 (fr) * | 1985-07-16 | 1987-11-27 | Eurofarad | Procede de fabrication d'un composant capacitif multicouche a dielectrique ceramique du type cordierite, et composant ainsi obtenu |
IE63321B1 (en) * | 1986-02-03 | 1995-04-05 | Elan Corp Plc | Drug delivery system |
SE8601624D0 (sv) * | 1986-04-11 | 1986-04-11 | Haessle Ab | New pharmaceutical preparations |
GB8613689D0 (en) * | 1986-06-05 | 1986-07-09 | Euro Celtique Sa | Pharmaceutical composition |
US4970075A (en) * | 1986-07-18 | 1990-11-13 | Euroceltique, S.A. | Controlled release bases for pharmaceuticals |
IE59540B1 (en) * | 1987-01-09 | 1994-03-09 | Elan Corp | Sustained release capsule or tablet formulation |
US4968508A (en) * | 1987-02-27 | 1990-11-06 | Eli Lilly And Company | Sustained release matrix |
GB8722306D0 (en) * | 1987-09-22 | 1987-10-28 | Aps Research Ltd | Sustained-release formulation |
GB8903328D0 (en) * | 1989-02-14 | 1989-04-05 | Ethical Pharma Ltd | Nifedipine-containing pharmaceutical compositions and process for the preparation thereof |
ATE124864T1 (de) * | 1989-03-10 | 1995-07-15 | Yamanouchi Pharma Co Ltd | Die wirkstoffabgabe steuerndes überzugsmaterial für lang wirksame formulierungen. |
HU203041B (en) * | 1989-03-14 | 1991-05-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing pharmaceutical compositions of controlled releasing factor containing nifedipin |
JPH0729926B2 (ja) * | 1989-07-25 | 1995-04-05 | 大塚製薬株式会社 | 易吸収性製剤用組成物 |
-
1992
- 1992-01-13 GB GB929200607A patent/GB9200607D0/en active Pending
-
1993
- 1993-01-11 IS IS3966A patent/IS1620B/is unknown
- 1993-01-12 CA CA002126864A patent/CA2126864A1/en not_active Abandoned
- 1993-01-12 NZ NZ246374A patent/NZ246374A/en unknown
- 1993-01-12 AU AU32636/93A patent/AU659529B2/en not_active Ceased
- 1993-01-12 DK DK93901850T patent/DK0620733T3/da active
- 1993-01-12 ZA ZA93195A patent/ZA93195B/xx unknown
- 1993-01-12 GB GB9413101A patent/GB2277872B/en not_active Expired - Fee Related
- 1993-01-12 MY MYPI93000048A patent/MY110660A/en unknown
- 1993-01-12 PL PL93300638A patent/PL170935B1/pl unknown
- 1993-01-12 WO PCT/GB1993/000055 patent/WO1993013773A1/en active IP Right Grant
- 1993-01-12 EP EP93901850A patent/EP0620733B1/en not_active Expired - Lifetime
- 1993-01-12 HU HU9401850A patent/HU219338B/hu not_active IP Right Cessation
- 1993-01-12 NL NL9320021A patent/NL9320021A/nl not_active Application Discontinuation
- 1993-01-12 PT PT93901850T patent/PT620733E/pt unknown
- 1993-01-12 RU RU94035739A patent/RU2106139C1/ru active
- 1993-01-12 ES ES93901850T patent/ES2146227T3/es not_active Expired - Lifetime
- 1993-01-12 AT AT93901850T patent/ATE191144T1/de not_active IP Right Cessation
- 1993-01-12 DE DE4390075T patent/DE4390075T1/de not_active Withdrawn
- 1993-01-12 US US08/256,398 patent/US5594013A/en not_active Expired - Lifetime
- 1993-01-12 DE DE69328245T patent/DE69328245T2/de not_active Expired - Fee Related
- 1993-01-12 PH PH45554A patent/PH30985A/en unknown
- 1993-01-12 JP JP5512264A patent/JPH07503003A/ja active Pending
-
1994
- 1994-07-11 DK DK083794A patent/DK83794A/da not_active Application Discontinuation
- 1994-07-12 FI FI943316A patent/FI943316A/fi unknown
- 1994-07-12 SE SE9402457A patent/SE9402457L/ not_active Application Discontinuation
- 1994-07-12 NO NO942622A patent/NO305223B1/no unknown
-
1995
- 1995-01-11 HU HU95P/P00065P patent/HU210539A9/hu unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2146227T3 (es) | Composiciones farmaceuticas que contienen nifedipina y procedimiento para su preparacion. | |
GR3030084T3 (en) | Sprayable film forming system releasing active substances for use on plants | |
AU635021B2 (en) | Extended release pharmaceutical formulations | |
NZ236188A (en) | Delayed release composition containing amorphous amylose and a coating containing a film-forming cellulose or acrylic polymer | |
SE9502244D0 (sv) | A composition and a process for the preparation thereof | |
DE69310602D1 (de) | 3',5'-Ditertbutyl-4'-Hydroxyflavone, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzung mit Antioxidations- und Antivasokonstriktionsaktivität | |
ES2102056T3 (es) | Composicion cosmetica que contiene unas particulas solidas revestidas con un polimero anfotero. | |
ATE143269T1 (de) | Alginatfasern mit verzögerter wirkstofffreigabe und verfahren zu deren herstellung | |
ATE154235T1 (de) | Kosmetische oder pharmazeutische zusammensetzungen zur topischen anwendung die deacylierten glycerophospholipide enthalten | |
PT920336E (pt) | Pesticidas que compreendem alcaloides da benzofenantridina | |
DK0689441T3 (da) | Farmaceutisk præparat i form af et kit omfattende prostaglandin E1 | |
AU4516793A (en) | The use of 1,3-dioxanes in lubricant and release agents |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Grant refused |
Effective date: 19940128 |
|
FG2A | Definitive protection |
Ref document number: 620733 Country of ref document: ES |