ES2144700T3 - Preparacion de tiazoles sustituidos. - Google Patents
Preparacion de tiazoles sustituidos.Info
- Publication number
- ES2144700T3 ES2144700T3 ES96306214T ES96306214T ES2144700T3 ES 2144700 T3 ES2144700 T3 ES 2144700T3 ES 96306214 T ES96306214 T ES 96306214T ES 96306214 T ES96306214 T ES 96306214T ES 2144700 T3 ES2144700 T3 ES 2144700T3
- Authority
- ES
- Spain
- Prior art keywords
- sub
- preparation
- substituted
- tiazoles
- atomo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- FZWLAAWBMGSTSO-UHFFFAOYSA-N Thiazole Chemical class C1=CSC=N1 FZWLAAWBMGSTSO-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000003905 agrochemical Substances 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000005660 chlorination reaction Methods 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
UN PROCESO PARA LA PREPARACION DE UN TIAZOL SUSTITUIDO COMPRENDE LA REACCION DE UN COMPUESTO DE ISOTIOCIANATO DE LA FORMULA GENERAL HAL.CH(()R{SUB,1}()).CH=C(()R{SUB,2}()).NCS, EN LA QUE HAL ES UN ATOMO DE CLORO O BROMO Y R{SUB,1} Y R{SUB,2} SON CADA UNO UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO QUE CONTIENE DE 1 A 3 ATOMOS DE CARBONO, EN SOLUCION CON UN AGENTE DE CLORACION O BROMURACION. EL COMPUESTO 2-CLORO-5-(CLOROMETIL) TIAZOL, QUE ES UN IMPORTANTE INTERMEDIARIO EN LA FABRICACION DE PRODUCTOS AGROQUIMICOS Y FARMACEUTICOS, PUEDE PREPARARSE DE FORMA MUY VENTAJOSA MEDIANTE ESTE METODO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9518824.9A GB9518824D0 (en) | 1995-09-14 | 1995-09-14 | Preparation of substituted thiazoles |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2144700T3 true ES2144700T3 (es) | 2000-06-16 |
Family
ID=10780723
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96306214T Expired - Lifetime ES2144700T3 (es) | 1995-09-14 | 1996-08-28 | Preparacion de tiazoles sustituidos. |
Country Status (18)
Country | Link |
---|---|
US (1) | US5705652A (es) |
EP (1) | EP0763531B1 (es) |
JP (1) | JP3168319B2 (es) |
KR (1) | KR970015581A (es) |
CN (1) | CN1064961C (es) |
AT (1) | ATE190975T1 (es) |
CA (1) | CA2186167C (es) |
DE (1) | DE69607272T2 (es) |
DK (1) | DK0763531T3 (es) |
ES (1) | ES2144700T3 (es) |
FI (1) | FI119244B (es) |
GB (1) | GB9518824D0 (es) |
GR (1) | GR3033620T3 (es) |
HU (1) | HU224038B1 (es) |
IN (1) | IN183678B (es) |
NO (1) | NO306298B1 (es) |
PT (1) | PT763531E (es) |
TW (1) | TW355708B (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IN182219B (es) * | 1996-02-21 | 1999-02-06 | Kuraray Co | |
AU6965398A (en) * | 1997-04-07 | 1998-10-30 | Reilly Industries, Inc. | Preparation of thiazoles using 1,3-dihalopropenes |
WO1998045277A1 (en) * | 1997-04-07 | 1998-10-15 | Reilly Industries, Inc. | Preparation of heterocycles using 1,3-dihalopropenes |
US5959118A (en) * | 1997-08-29 | 1999-09-28 | Abbott Laboratories | Process for the preparation of 5-hydroxymethylthiazoles |
DE19908447A1 (de) | 1999-02-26 | 2000-08-31 | Bayer Ag | Verfahren zur Herstellung von 2-Chlor-5-chlormethylthiazol |
ES2194783T3 (es) | 1999-11-15 | 2003-12-01 | Dsm Fine Chem Austria Gmbh | Procedimiento para la obtencion de 2-cloro-5-clorome-til-1,3-tiazol. |
AT409760B (de) * | 1999-11-15 | 2002-11-25 | Dsm Fine Chem Austria Gmbh | Verfahren zur herstellung von 2-chlor-5-chlormethyl-1,3-thiazol |
AT408756B (de) * | 2000-05-23 | 2002-03-25 | Dsm Fine Chem Austria Gmbh | Verfahren zur herstellung von 2-chlor-5-chlormethyl-1,3-thiazol |
WO2002012209A1 (de) * | 2000-08-10 | 2002-02-14 | Bayer Cropscience Ag | Verfahren zur reinigung von 2-chlor-5-chlormethylthiazol |
DE10061083A1 (de) * | 2000-12-08 | 2002-06-13 | Bayer Ag | Bis-(2-chlor-thiazolyl-5-methyl)-amin und seine Salze sowie Verfahren zur Aufarbeitung von 5-Aminomethyl-2-chlor-thiazol und Bis-(2-chlor-thiazol-5-methyl)-amin enthaltenden Reaktionsgemischen |
BRPI0508698B1 (pt) | 2004-03-22 | 2015-06-02 | Sumitomo Chemical Co | Processo para a purificação de 2-cloro-5-clorometil-1,3-tiazol |
CN102503872A (zh) * | 2011-12-15 | 2012-06-20 | 常州大学 | 一种制备异硫氰酸酯的方法 |
CN103772315B (zh) * | 2014-01-07 | 2015-10-21 | 山东汇海医药化工有限公司 | 一种一步合成4-甲基噻唑-5-甲酸乙酯的方法 |
CN103755661B (zh) * | 2014-02-08 | 2016-09-21 | 山东省农药科学研究院 | 一种2-氯-5-氯甲基噻唑的分离精制方法 |
TWI620558B (zh) | 2016-12-20 | 2018-04-11 | 富伯生醫科技股份有限公司 | 穿戴式手部復健輔具系統 |
CN109293596A (zh) * | 2018-09-30 | 2019-02-01 | 江苏润泽鑫生物科技有限公司 | 2-氯-5-氯甲基噻唑的制备方法 |
CN113121465A (zh) * | 2021-05-28 | 2021-07-16 | 安徽海顺化工有限公司 | 一种2-氯-5-氯甲基噻唑的合成工艺 |
KR102610076B1 (ko) * | 2022-04-29 | 2023-12-04 | 윤필영 | 쿨링 기능성 퀼팅 덮는 이불 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3631538A1 (de) * | 1986-09-17 | 1988-03-24 | Bayer Ag | Verfahren zur herstellung von 2-chlor-5-chlormethylthiazol |
US5180833A (en) * | 1990-03-16 | 1993-01-19 | Takeda Chemical Industries, Ltd. | Process for the preparation of chlorothiazole derivatives |
-
1995
- 1995-09-14 GB GBGB9518824.9A patent/GB9518824D0/en active Pending
-
1996
- 1996-08-26 IN IN1508CA1996 patent/IN183678B/en unknown
- 1996-08-27 FI FI963344A patent/FI119244B/fi active IP Right Grant
- 1996-08-28 DE DE69607272T patent/DE69607272T2/de not_active Expired - Lifetime
- 1996-08-28 ES ES96306214T patent/ES2144700T3/es not_active Expired - Lifetime
- 1996-08-28 PT PT96306214T patent/PT763531E/pt unknown
- 1996-08-28 AT AT96306214T patent/ATE190975T1/de not_active IP Right Cessation
- 1996-08-28 DK DK96306214T patent/DK0763531T3/da active
- 1996-08-28 EP EP96306214A patent/EP0763531B1/en not_active Expired - Lifetime
- 1996-09-09 US US08/711,228 patent/US5705652A/en not_active Expired - Lifetime
- 1996-09-12 KR KR1019960039421A patent/KR970015581A/ko active IP Right Grant
- 1996-09-13 CA CA002186167A patent/CA2186167C/en not_active Expired - Fee Related
- 1996-09-13 JP JP24285196A patent/JP3168319B2/ja not_active Expired - Fee Related
- 1996-09-13 NO NO963829A patent/NO306298B1/no not_active IP Right Cessation
- 1996-09-13 HU HU9602510A patent/HU224038B1/hu not_active IP Right Cessation
- 1996-09-14 TW TW085111252A patent/TW355708B/zh not_active IP Right Cessation
- 1996-09-16 CN CN961134194A patent/CN1064961C/zh not_active Expired - Fee Related
-
2000
- 2000-06-07 GR GR20000401306T patent/GR3033620T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR970015581A (ko) | 1997-04-28 |
NO963829D0 (no) | 1996-09-13 |
HUP9602510A3 (en) | 1999-03-29 |
CA2186167C (en) | 2007-07-24 |
DE69607272D1 (de) | 2000-04-27 |
EP0763531A1 (en) | 1997-03-19 |
EP0763531B1 (en) | 2000-03-22 |
IN183678B (es) | 2000-03-18 |
DE69607272T2 (de) | 2000-07-13 |
CA2186167A1 (en) | 1997-03-15 |
HUP9602510A1 (en) | 1997-05-28 |
JPH09110844A (ja) | 1997-04-28 |
FI963344A0 (fi) | 1996-08-27 |
US5705652A (en) | 1998-01-06 |
NO963829L (no) | 1997-03-17 |
NO306298B1 (no) | 1999-10-18 |
DK0763531T3 (da) | 2000-07-10 |
CN1064961C (zh) | 2001-04-25 |
FI119244B (fi) | 2008-09-15 |
TW355708B (en) | 1999-04-11 |
HU224038B1 (hu) | 2005-05-30 |
JP3168319B2 (ja) | 2001-05-21 |
GB9518824D0 (en) | 1995-11-15 |
ATE190975T1 (de) | 2000-04-15 |
FI963344A (fi) | 1997-03-15 |
CN1152571A (zh) | 1997-06-25 |
PT763531E (pt) | 2000-08-31 |
GR3033620T3 (en) | 2000-10-31 |
HU9602510D0 (en) | 1996-11-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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