ES2143671T3 - Antiarritmicos (s)-enantiomeros de metanosulfonamidas. - Google Patents
Antiarritmicos (s)-enantiomeros de metanosulfonamidas.Info
- Publication number
- ES2143671T3 ES2143671T3 ES95943727T ES95943727T ES2143671T3 ES 2143671 T3 ES2143671 T3 ES 2143671T3 ES 95943727 T ES95943727 T ES 95943727T ES 95943727 T ES95943727 T ES 95943727T ES 2143671 T3 ES2143671 T3 ES 2143671T3
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- formula
- methanosulphonamides
- enantiomeros
- antiarrhythmic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
LAS METANOSULFONAMIDAS (S) O SUS SALES FARMACOLOGICAMENTE ACEPTABLES, EN LA QUE R{SUB,3} ES UN ALQUILO C{SUB,1-9} SUSTITUIDO POR UN ATOMO DE FLUOR. ESTOS COMPUESTOS RESULTAN UTILES COMO AGENTES ANTIARRITMICOS DE CLASE III, SIN QUE PRESENTEN EL EFECTO SECUNDARIO INDESEABLE DE TAQUICARDIA VENTRICULAR POLIMORFICA (TVP), Y SON ESTABLES FRENTE A UN METABOLISMO RAPIDO. TAMBIEN SE DESCRIBE EL USO DE LOS COMPUESTOS DE FORMULA (I) EN LA PREPARACION DE COMPOSICIONES PARA TRATAR ARRITMIAS CARDIACAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37153395A | 1995-01-10 | 1995-01-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2143671T3 true ES2143671T3 (es) | 2000-05-16 |
Family
ID=23464353
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95943727T Expired - Lifetime ES2143671T3 (es) | 1995-01-10 | 1995-12-21 | Antiarritmicos (s)-enantiomeros de metanosulfonamidas. |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0802900B1 (es) |
JP (1) | JP3846899B2 (es) |
CN (1) | CN1057758C (es) |
AT (1) | ATE189809T1 (es) |
AU (1) | AU691075B2 (es) |
CA (1) | CA2207545C (es) |
DE (1) | DE69515133T2 (es) |
DK (1) | DK0802900T3 (es) |
ES (1) | ES2143671T3 (es) |
GR (1) | GR3033396T3 (es) |
HK (1) | HK1008896A1 (es) |
NO (1) | NO308735B1 (es) |
NZ (1) | NZ300400A (es) |
PT (1) | PT802900E (es) |
WO (1) | WO1996021643A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101412687B (zh) * | 2008-11-10 | 2012-01-11 | 浙江师范大学 | 旋光纯富马酸伊布利特的制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1237079A (en) * | 1983-05-23 | 1988-05-24 | Arthur Simon | Antiarrhythmic class iii process |
DK0484378T3 (da) * | 1989-07-25 | 1995-02-20 | Upjohn Co | Antiarytmiske tertiær amin-alkenyl-phenyl-alkansulfonamider |
CA2103932A1 (en) * | 1992-11-05 | 1994-05-06 | Ramesh N. Patel | Stereoselective reduction of ketones |
-
1995
- 1995-12-21 NZ NZ300400A patent/NZ300400A/xx unknown
- 1995-12-21 WO PCT/US1995/016017 patent/WO1996021643A1/en active IP Right Grant
- 1995-12-21 DK DK95943727T patent/DK0802900T3/da active
- 1995-12-21 PT PT95943727T patent/PT802900E/pt unknown
- 1995-12-21 CA CA002207545A patent/CA2207545C/en not_active Expired - Fee Related
- 1995-12-21 AT AT95943727T patent/ATE189809T1/de not_active IP Right Cessation
- 1995-12-21 AU AU45130/96A patent/AU691075B2/en not_active Ceased
- 1995-12-21 DE DE69515133T patent/DE69515133T2/de not_active Expired - Fee Related
- 1995-12-21 JP JP52165896A patent/JP3846899B2/ja not_active Expired - Fee Related
- 1995-12-21 ES ES95943727T patent/ES2143671T3/es not_active Expired - Lifetime
- 1995-12-21 EP EP95943727A patent/EP0802900B1/en not_active Expired - Lifetime
- 1995-12-21 CN CN95197287A patent/CN1057758C/zh not_active Expired - Fee Related
-
1997
- 1997-07-09 NO NO973181A patent/NO308735B1/no not_active IP Right Cessation
-
1998
- 1998-08-04 HK HK98109661A patent/HK1008896A1/xx not_active IP Right Cessation
-
2000
- 2000-05-11 GR GR20000401084T patent/GR3033396T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DK0802900T3 (da) | 2000-06-13 |
NZ300400A (en) | 1998-10-28 |
GR3033396T3 (en) | 2000-09-29 |
WO1996021643A1 (en) | 1996-07-18 |
CA2207545C (en) | 2008-02-26 |
DE69515133T2 (de) | 2000-07-13 |
NO308735B1 (no) | 2000-10-23 |
EP0802900A1 (en) | 1997-10-29 |
DE69515133D1 (de) | 2000-03-23 |
JPH11500418A (ja) | 1999-01-12 |
CA2207545A1 (en) | 1996-07-18 |
JP3846899B2 (ja) | 2006-11-15 |
AU4513096A (en) | 1996-07-31 |
CN1172475A (zh) | 1998-02-04 |
AU691075B2 (en) | 1998-05-07 |
NO973181L (no) | 1997-07-09 |
ATE189809T1 (de) | 2000-03-15 |
HK1008896A1 (en) | 1999-07-23 |
NO973181D0 (no) | 1997-07-09 |
CN1057758C (zh) | 2000-10-25 |
PT802900E (pt) | 2000-07-31 |
EP0802900B1 (en) | 2000-02-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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