ES2143507T3 - Vacunas contra la enfermedad de aujeszky y de otras enfermedades animales que contienen mutantes del virus de la pseudorrabia. - Google Patents
Vacunas contra la enfermedad de aujeszky y de otras enfermedades animales que contienen mutantes del virus de la pseudorrabia.Info
- Publication number
- ES2143507T3 ES2143507T3 ES93916297T ES93916297T ES2143507T3 ES 2143507 T3 ES2143507 T3 ES 2143507T3 ES 93916297 T ES93916297 T ES 93916297T ES 93916297 T ES93916297 T ES 93916297T ES 2143507 T3 ES2143507 T3 ES 2143507T3
- Authority
- ES
- Spain
- Prior art keywords
- viruses
- pseudorrabia
- animal diseases
- vaccines against
- gene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229960005486 vaccine Drugs 0.000 title abstract 4
- 241000700605 Viruses Species 0.000 title abstract 3
- 208000031295 Animal disease Diseases 0.000 title abstract 2
- 208000009305 pseudorabies Diseases 0.000 title abstract 2
- 241001465754 Metazoa Species 0.000 abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 230000035772 mutation Effects 0.000 abstract 3
- 108010059485 brain synaptic membrane glycoprotein gp 50 Proteins 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16761—Methods of inactivation or attenuation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
LA INVENCION SUMINISTRA VACUNAS PARA PREVENIR Y CONTROLAR ENFERMEDADES EN ANIMALES, QUE COMPRENDEN UN VIRUS DE PSEUDO-CONEJO QUE CONTIENE LA GLICOPROTEINA GP50 Y QUE TIENE UNA MUTACION EN SU GEN GP50. LAS VACUNAS SON ADECUADAS PARA SU USO CONTRA LA ENFERMEDAD DE AUJESZKY (PSEUDO-CONEJO), O CONTRA OTRAS ENFERMEDADES ANIMALES CUANDO LA MUTACION ES UNA INSERCION QUE COMPRENDE UN GEN HETEROLOGO QUE CODIFICA UN ANTIGENO QUE SE CORRESPONDE CON DICHA ENFERMEDAD DEL ANIMAL. LOS VIRUS DE PSEUDO-CONEJOS PUEDE TENER ADICIONALMENTE AL MENOS UNA MUTACION EN UNO DE SUS OTROS GENES, TAL COMO EL GEN GP63 O EL GEN GI. LAS VACUNAS SON INCAPACES DE CONTAGIAR DE ANIMALES VACUNADOS A ANIMALES NO VACUNADOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP92202096 | 1992-07-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2143507T3 true ES2143507T3 (es) | 2000-05-16 |
Family
ID=8210764
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93916297T Expired - Lifetime ES2143507T3 (es) | 1992-07-09 | 1993-07-08 | Vacunas contra la enfermedad de aujeszky y de otras enfermedades animales que contienen mutantes del virus de la pseudorrabia. |
Country Status (18)
Country | Link |
---|---|
US (1) | US5674500A (es) |
EP (1) | EP0654086B1 (es) |
JP (1) | JPH07509127A (es) |
KR (1) | KR100341994B1 (es) |
CN (1) | CN1124159C (es) |
AT (1) | ATE189000T1 (es) |
AU (1) | AU684252B2 (es) |
CA (1) | CA2139507C (es) |
DE (1) | DE69327656T2 (es) |
DK (1) | DK0654086T3 (es) |
ES (1) | ES2143507T3 (es) |
HU (1) | HU220099B (es) |
NZ (1) | NZ254267A (es) |
PL (1) | PL174219B1 (es) |
RU (1) | RU2158308C2 (es) |
TW (1) | TW289731B (es) |
WO (1) | WO1994001573A1 (es) |
ZA (1) | ZA934882B (es) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0587780T4 (da) * | 1991-06-06 | 2008-10-13 | Boehringer Ingelheim Vetmed | Smitstof, som forårsager Mystery Swine Disease,vaccinepræparater og diagnostiske sæt |
US6007825A (en) * | 1991-12-23 | 1999-12-28 | American Cyanamid Company | Serpulina hyodysenteriae vaccine comprising a tly gene mutant |
US7223411B1 (en) | 1992-07-31 | 2007-05-29 | Dana-Farber Cancer Institute | Herpesvirus replication defective mutants |
US6773908B1 (en) * | 1992-10-30 | 2004-08-10 | Iowa State University Research Foundation, Inc. | Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV) |
US5695766A (en) * | 1992-10-30 | 1997-12-09 | Iowa State University Research Foundation | Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome |
US6592873B1 (en) | 1992-10-30 | 2003-07-15 | Iowa State University Research Foundation, Inc. | Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids |
US6380376B1 (en) * | 1992-10-30 | 2002-04-30 | Iowa State University Research Foundation | Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV) |
AU696336B2 (en) * | 1993-03-19 | 1998-09-10 | Cantab Pharmaceuticals Research Limited | Defective mutant non-retroviral virus (e.g. HSV) as vaccine |
EP0659885A1 (en) * | 1993-12-21 | 1995-06-28 | Akzo Nobel N.V. | Vaccine against viruses associated with antibody-dependent-enhancement of viral infectivity |
EP0693551A1 (en) * | 1994-07-18 | 1996-01-24 | Akzo Nobel N.V. | gD-negative bovine herpesvirus mutant, capable of direct cell-to-cell transmission |
EP0839912A1 (en) * | 1996-10-30 | 1998-05-06 | Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
US20040224327A1 (en) * | 1996-10-30 | 2004-11-11 | Meulenberg Johanna Jacoba Maria | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
US6399354B1 (en) | 1998-07-31 | 2002-06-04 | President And Fellows Of Harvard College | Replication-competent virus expressing a detectable fusion protein |
EP1157121B1 (en) * | 1999-03-08 | 2013-04-24 | Boehringer Ingelheim Vetmedica GmbH | Prrsv replicon |
DK2251419T3 (da) * | 1999-04-22 | 2012-07-02 | Us Agriculture | Porcint reproduktions- og respirations-syndrom-vaccine baseret på isolat JA-142 |
CA2509494A1 (en) * | 2002-12-11 | 2004-06-24 | University Of Massachusetts | Method of introducing sirna into adipocytes |
BRPI0510928A (pt) * | 2004-06-18 | 2007-11-13 | Univ Minnesota | identificação de organismos viralmente infectados e vacinados |
US7632636B2 (en) * | 2004-09-21 | 2009-12-15 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome isolates and methods of use |
MX2007015849A (es) | 2005-06-24 | 2008-02-22 | Univ Minnesota | Virus del sindrome respiratorio y reproductivo porcino, clones infecciosos, mutantes de los mismos, y metodos de uso. |
CN101081298A (zh) * | 2007-06-26 | 2007-12-05 | 陈少莺 | 一种猪伪狂犬病新型亚单位疫苗制备方法 |
BRPI0917887A2 (pt) * | 2008-08-25 | 2019-09-03 | Boehringer Ingelheim Vetmedica Inc | vacina contra síndrome reprodutiva e respiratória suína altamente patogênica (hp pprs) |
CN101457215B (zh) * | 2008-12-01 | 2010-11-17 | 华中农业大学 | 重组猪伪狂犬病毒-猪繁殖与呼吸综合征病毒-猪圆环病毒基因工程毒株及应用 |
AR078253A1 (es) * | 2009-09-02 | 2011-10-26 | Boehringer Ingelheim Vetmed | Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad |
CA2827337C (en) | 2011-02-17 | 2019-07-09 | Boehringer Ingelheim Vetmedica Gmbh | Commercial scale process for production of prrsv |
DK2959916T3 (en) | 2011-02-17 | 2018-10-29 | Boehringer Ingelheim Vetmedica Gmbh | New European PRRSV strain. |
EP2737059A1 (en) | 2011-07-29 | 2014-06-04 | Boehringer Ingelheim Vetmedica GmbH | Novel prrs virus inducing type i interferon in susceptible cells |
US9187731B2 (en) | 2011-07-29 | 2015-11-17 | Boehringer Ingelheim Vetmedica Gmbh | PRRS virus inducing type I interferon in susceptible cells |
US9579373B2 (en) | 2013-03-15 | 2017-02-28 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use |
CN104250640A (zh) * | 2014-08-22 | 2014-12-31 | 普莱柯生物工程股份有限公司 | 猪伪狂犬病病毒基因缺失株、疫苗组合物及其制备方法和应用 |
CN111560355A (zh) * | 2015-03-20 | 2020-08-21 | 普莱柯生物工程股份有限公司 | 一种猪伪狂犬病病毒致弱方法、及其致弱的病毒株、疫苗组合物和应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE60799T1 (de) * | 1985-07-29 | 1991-02-15 | Upjohn Co | Virus-impfstoff. |
US5352575A (en) * | 1985-10-04 | 1994-10-04 | The Upjohn Company | Pseudorabies virus protein |
US4999296A (en) * | 1986-04-29 | 1991-03-12 | Novagene, Inc. | Thymidine kinase negative insertion mutants of pseudorabies virus and methods for the production of same |
NL8902087A (nl) * | 1989-08-17 | 1991-03-18 | Stichting Tech Wetenschapp | Niet-natuurlijk voorkomend pseudorabiesvirus en vaccins die dit bevatten. |
JP3895366B2 (ja) * | 1990-09-25 | 2007-03-22 | キャンタブ ファーマシューティカルズ リサーチ リミティド | ウィルス ワクチン |
WO1994003595A1 (en) * | 1992-07-30 | 1994-02-17 | Akzo Nobel N.V. | Non-shedding live herpesvirus vaccine |
-
1993
- 1993-07-02 TW TW82105279A patent/TW289731B/zh active
- 1993-07-07 ZA ZA934882A patent/ZA934882B/xx unknown
- 1993-07-08 US US08/373,325 patent/US5674500A/en not_active Expired - Fee Related
- 1993-07-08 HU HU9500039A patent/HU220099B/hu not_active IP Right Cessation
- 1993-07-08 DE DE1993627656 patent/DE69327656T2/de not_active Expired - Fee Related
- 1993-07-08 JP JP6503188A patent/JPH07509127A/ja active Pending
- 1993-07-08 RU RU95105518A patent/RU2158308C2/ru not_active IP Right Cessation
- 1993-07-08 CA CA 2139507 patent/CA2139507C/en not_active Expired - Fee Related
- 1993-07-08 WO PCT/NL1993/000146 patent/WO1994001573A1/en active IP Right Grant
- 1993-07-08 KR KR1019950700064A patent/KR100341994B1/ko not_active IP Right Cessation
- 1993-07-08 PL PL93307049A patent/PL174219B1/pl not_active IP Right Cessation
- 1993-07-08 ES ES93916297T patent/ES2143507T3/es not_active Expired - Lifetime
- 1993-07-08 DK DK93916297T patent/DK0654086T3/da active
- 1993-07-08 EP EP19930916297 patent/EP0654086B1/en not_active Expired - Lifetime
- 1993-07-08 NZ NZ254267A patent/NZ254267A/en unknown
- 1993-07-08 AU AU45898/93A patent/AU684252B2/en not_active Ceased
- 1993-07-08 AT AT93916297T patent/ATE189000T1/de not_active IP Right Cessation
- 1993-07-09 CN CN93108005A patent/CN1124159C/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DK0654086T3 (da) | 2000-06-13 |
JPH07509127A (ja) | 1995-10-12 |
CA2139507A1 (en) | 1994-01-20 |
ATE189000T1 (de) | 2000-02-15 |
KR100341994B1 (ko) | 2002-11-30 |
PL174219B1 (pl) | 1998-06-30 |
CN1124159C (zh) | 2003-10-15 |
AU4589893A (en) | 1994-01-31 |
HUT70986A (en) | 1995-11-28 |
HU9500039D0 (en) | 1995-03-28 |
CN1086143A (zh) | 1994-05-04 |
WO1994001573A1 (en) | 1994-01-20 |
PL307049A1 (en) | 1995-05-02 |
RU2158308C2 (ru) | 2000-10-27 |
DE69327656D1 (de) | 2000-02-24 |
NZ254267A (en) | 1996-08-27 |
US5674500A (en) | 1997-10-07 |
AU684252B2 (en) | 1997-12-11 |
RU95105518A (ru) | 1997-03-27 |
EP0654086B1 (en) | 2000-01-19 |
TW289731B (es) | 1996-11-01 |
CA2139507C (en) | 2005-04-19 |
HU220099B (hu) | 2001-10-28 |
DE69327656T2 (de) | 2000-08-03 |
EP0654086A1 (en) | 1995-05-24 |
ZA934882B (en) | 1994-02-03 |
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