ES2141496T3 - Preparacion de formulaciones para la administracion de medicamento mediante electrotransporte. - Google Patents

Preparacion de formulaciones para la administracion de medicamento mediante electrotransporte.

Info

Publication number
ES2141496T3
ES2141496T3 ES96913866T ES96913866T ES2141496T3 ES 2141496 T3 ES2141496 T3 ES 2141496T3 ES 96913866 T ES96913866 T ES 96913866T ES 96913866 T ES96913866 T ES 96913866T ES 2141496 T3 ES2141496 T3 ES 2141496T3
Authority
ES
Spain
Prior art keywords
drug
electrotransportation
medicines
formulations
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96913866T
Other languages
English (en)
Inventor
Thomas Owen Murdock
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ES2141496T3 publication Critical patent/ES2141496T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Electrotherapy Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE DESCRIBE UN PROCEDIMIENTO PARA PREPARAR FORMULADOS DE FARMACOS QUE RESULTAN ADECUADOS PARA LA ADMINISTRACION DE FARMACOS POR ELECTROTRANSPORTE. EL FARMACO QUE SE VA A ADMINISTRAR, PRESENTE EN SU FORMA SALINA, SE PONE EN CONTACTO CON UN MATERIAL DE INTERCAMBIO IONICO ANTES DE SU INCORPORACION AL DEPOSITO (26) DE UN SISTEMA DE ADMINISTRACION POR ELECTROTRANSPORTE (10). DE ESTA MANERA, LA SAL DEL FARMACO SE NEUTRALIZA PARCIAL O COMPLETAMENTE. ESTA TECNICA RESULTA UTIL PARA AJUSTAR EL PH DEL FORMULADO DE FARMACO SIN INCORPORAR MATERIALES EXTRAÑOS, POR EJEMPLO IONES COMPETITIVOS O SIMILARES, EN EL DEPOSITO (26).
ES96913866T 1995-05-03 1996-04-19 Preparacion de formulaciones para la administracion de medicamento mediante electrotransporte. Expired - Lifetime ES2141496T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/433,173 US5853383A (en) 1995-05-03 1995-05-03 Preparation for formulations for electrotransport drug delivery

Publications (1)

Publication Number Publication Date
ES2141496T3 true ES2141496T3 (es) 2000-03-16

Family

ID=23719114

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96913866T Expired - Lifetime ES2141496T3 (es) 1995-05-03 1996-04-19 Preparacion de formulaciones para la administracion de medicamento mediante electrotransporte.

Country Status (8)

Country Link
US (2) US5853383A (es)
EP (1) EP0824342B1 (es)
JP (1) JP4026850B2 (es)
AT (1) ATE186835T1 (es)
DE (1) DE69605298T2 (es)
DK (1) DK0824342T3 (es)
ES (1) ES2141496T3 (es)
WO (1) WO1996034597A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5983130A (en) * 1995-06-07 1999-11-09 Alza Corporation Electrotransport agent delivery method and apparatus
AU754882B2 (en) * 1996-02-20 2002-11-28 Computer Motion, Inc. A method and apparatus for performing minimally invasive cardiac procedures
US6718201B1 (en) * 1996-06-07 2004-04-06 Alza Corporation Electrotransport agent delivery method and apparatus
US5991655A (en) * 1997-03-03 1999-11-23 Drug Delivery Systems, Inc. Iontophoretic drug delivery device and method of manufacturing the same
EP1109594B1 (en) 1998-08-31 2004-10-27 Johnson & Johnson Consumer Companies, Inc. Electrotransport device comprising blades
EP1171195B1 (en) 1999-04-16 2005-03-16 Johnson & Johnson Consumer Companies, Inc. Electrotransport delivery system comprising internal sensors
US6890553B1 (en) 1999-07-08 2005-05-10 Johnson & Johnson Consumer Companies, Inc. Exothermic topical delivery device
AU6076200A (en) 1999-07-08 2001-01-30 Johnson & Johnson Consumer Companies, Inc. Exothermic bandage
US7133717B2 (en) * 1999-08-25 2006-11-07 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery and diagnostic sampling
US7113821B1 (en) 1999-08-25 2006-09-26 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery
JP4414517B2 (ja) 1999-09-01 2010-02-10 久光製薬株式会社 イオントフォレーシス用デバイス構造体
US7404815B2 (en) * 2000-05-01 2008-07-29 Lifescan, Inc. Tissue ablation by shear force for sampling biological fluids and delivering active agents
US6629968B1 (en) * 2000-06-30 2003-10-07 Vyteris, Inc. Shelf storage stable iontophoresis reservoir-electrode and iontophoretic system incorporating the reservoir-electrode
CN1273143C (zh) * 2000-09-11 2006-09-06 阿尔扎公司 经过皮肤电迁移器件及其制造方法
US6591133B1 (en) * 2000-11-27 2003-07-08 Microlin Llc Apparatus and methods for fluid delivery using electroactive needles and implantable electrochemical delivery devices
WO2003047689A1 (en) * 2001-11-29 2003-06-12 Microlin Llc Apparatus and methods for fluid delivery using electroactive needles and implantable electrochemical delivery devices
US7567313B2 (en) * 2003-07-10 2009-07-28 Avago Technologies Ecbu Ip (Singapore) Pte. Ltd. Bezel design for surface mount display modules
WO2005020912A2 (en) * 2003-08-25 2005-03-10 3M Innovative Properties Company Delivery of immune response modifier compounds
US20050142531A1 (en) * 2003-11-19 2005-06-30 David Rauser Peptidically buffered formulations for electrotransport applications and methods of making
US20070025869A1 (en) * 2005-07-15 2007-02-01 Gordon John H Fluid Delivery Device
US20080147186A1 (en) * 2006-12-14 2008-06-19 Joshi Ashok V Electrochemical Implant For Delivering Beneficial Agents

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2579283A (en) * 1950-07-21 1951-12-18 Du Pont Production of lysine monohydro-chloride
US4203440A (en) * 1978-10-23 1980-05-20 Alza Corporation Device having variable volume chamber for dispensing useful agent
US4203441A (en) * 1978-12-18 1980-05-20 Alza Corporation Osmotically triggered device with gas generating means
US4847077A (en) * 1984-07-18 1989-07-11 Pennwalt Corporation Controlled release pharmaceutical preparations
FR2576213B1 (fr) * 1985-01-21 1989-02-24 Cortial Nouveau procede d'obtention de formes pharmaceutiques a liberation prolongee
EP0199855A1 (en) * 1985-05-02 1986-11-05 Gist-Brocades N.V. Tablets comprising tromethoprim and a sulfonamide
US4722726A (en) * 1986-02-12 1988-02-02 Key Pharmaceuticals, Inc. Method and apparatus for iontophoretic drug delivery
US4915685A (en) * 1986-03-19 1990-04-10 Petelenz Tomasz J Methods and apparatus for iontophoresis application of medicaments at a controlled ph through ion exchange
US5080646A (en) * 1988-10-03 1992-01-14 Alza Corporation Membrane for electrotransport transdermal drug delivery
US4894239A (en) * 1987-06-02 1990-01-16 Takeda Chemical Industries, Ltd. Sustained-release preparation and production thereof
EP0318776A1 (en) * 1987-12-04 1989-06-07 Robert Tapper Method and apparatus for minimizing skin injury with electrode use
US5147296A (en) * 1988-10-03 1992-09-15 Alza Corporation Membrane for electrotransport transdermal drug delivery
US5169382A (en) * 1988-10-03 1992-12-08 Alza Corporation Membrane for electrotransport transdermal drug delivery
EP0429842B1 (en) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
SI9300097B (en) * 1992-02-27 2001-12-31 Janssen Pharmaceutica Nv (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines
GB2265088B (en) * 1992-03-10 1996-02-07 Kyosti Eero Antero Kontturi Electrochemical device for drug delivery
PH31437A (en) * 1993-08-27 1998-11-03 Janssen Pharmaceutica Nv Tontophoretic delivery of an antimigrane drug.

Also Published As

Publication number Publication date
EP0824342A1 (en) 1998-02-25
JPH11504923A (ja) 1999-05-11
WO1996034597A1 (en) 1996-11-07
US5853383A (en) 1998-12-29
DK0824342T3 (da) 2000-04-03
ATE186835T1 (de) 1999-12-15
JP4026850B2 (ja) 2007-12-26
US6071508A (en) 2000-06-06
DE69605298T2 (de) 2000-04-13
EP0824342B1 (en) 1999-11-24
DE69605298D1 (de) 1999-12-30

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