ES2133320T3 - Fragmentos peptidicos procedentes del citocromo humano p450 iid6, anticuerpos antifragmentos peptidicos y sus aplicaciones en el diagnostico en la hepatitis autoinmune. - Google Patents

Fragmentos peptidicos procedentes del citocromo humano p450 iid6, anticuerpos antifragmentos peptidicos y sus aplicaciones en el diagnostico en la hepatitis autoinmune.

Info

Publication number
ES2133320T3
ES2133320T3 ES92912543T ES92912543T ES2133320T3 ES 2133320 T3 ES2133320 T3 ES 2133320T3 ES 92912543 T ES92912543 T ES 92912543T ES 92912543 T ES92912543 T ES 92912543T ES 2133320 T3 ES2133320 T3 ES 2133320T3
Authority
ES
Spain
Prior art keywords
peptidic
iid6
applications
fragments
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92912543T
Other languages
English (en)
Inventor
Fernando Alvarez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Application granted granted Critical
Publication of ES2133320T3 publication Critical patent/ES2133320T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/82—Hepatitis associated antigens and antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

FRAGMENTOS PEPTIDICOS SALIDOS DEL CITOCROMO P450 IID6 HUMANO, ANTICUERPOS ANTIFRAGMENTOS PEPTIDICOS Y SUS APLICACIONES EN EL DIAGNOSTICO DE LA HEPATITIS AUTOINMUNE Y MAS EN PARTICULAR EN EL DIAGNOSTICO DIFERENCIAL ENTRE LA HEPATITIS AUTOINMUNE Y OTRAS HEPATITIS CRONICAS DE ORIGEN VIRICO, TALES COMO LA HEPATITIS C O LA HEPATITIS B. DICHO FRAGMENTO PEPTIDICO DEL CITOCROMO P450 HUMANO CONTIENE AL MENOS UN EPITOPE INMUNODOMINANTE DEL CITOCROMO P450 IID6, ESTA CONSTITUIDO POR UNA SECUENCIA DE AMINOACIDOS QUE COMPRENDE ENTRE 3 Y 70 AMINOACIDOS Y SE UNE ESPECIFICAMENTE CON LOS AUTO-ANTICUERPOS ANTI-LKM PRODUCIDOS DURANTE LA HEPATITIS AUTOINMUNE.
ES92912543T 1991-06-17 1992-06-16 Fragmentos peptidicos procedentes del citocromo humano p450 iid6, anticuerpos antifragmentos peptidicos y sus aplicaciones en el diagnostico en la hepatitis autoinmune. Expired - Lifetime ES2133320T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9107363A FR2677653A1 (fr) 1991-06-17 1991-06-17 Fragments peptidiques issus du cytochrome humain p450 iid6, anticorps anti-fragments peptidiques et leurs applications dans le diagnostic de l'hepatite auto-immune.

Publications (1)

Publication Number Publication Date
ES2133320T3 true ES2133320T3 (es) 1999-09-16

Family

ID=9413909

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92912543T Expired - Lifetime ES2133320T3 (es) 1991-06-17 1992-06-16 Fragmentos peptidicos procedentes del citocromo humano p450 iid6, anticuerpos antifragmentos peptidicos y sus aplicaciones en el diagnostico en la hepatitis autoinmune.

Country Status (9)

Country Link
US (1) US5830667A (es)
EP (1) EP0589993B1 (es)
JP (1) JP3284240B2 (es)
AT (1) ATE180512T1 (es)
CA (1) CA2111672A1 (es)
DE (1) DE69229269T2 (es)
ES (1) ES2133320T3 (es)
FR (1) FR2677653A1 (es)
WO (1) WO1992022656A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19721113A1 (de) * 1996-05-20 1997-11-27 Sumitomo Chemical Co Diagnosekit
DE19805815C1 (de) 1998-02-13 1999-11-11 Ansgar W Lohse Diagnostikum zum Erkennen der autoimmunen Hepatitis
DE19930933B4 (de) * 1998-07-10 2005-05-25 Imtec Immundiagnostika Gmbh Verfahren zur Bestimmung von anti-LKM 1-Antikörpern
US6787303B1 (en) 1999-04-01 2004-09-07 Alton Ochsner Medical Foundation Identification of a novel retrovirus associated with primary sclerosing cholangitis and autoimmune hepatitis
WO2002026832A1 (en) * 2000-09-29 2002-04-04 Merck & Co., Inc. Antibodies for human cytochrome p450 2d6
US20040096874A1 (en) * 2002-04-11 2004-05-20 Third Wave Technologies, Inc. Characterization of CYP 2D6 genotypes
WO2010006377A1 (en) * 2008-07-17 2010-01-21 Nutripep Pty Limited Therapeutic agents
CN102955026A (zh) * 2012-06-11 2013-03-06 郑州安图绿科生物工程有限公司 检测自身免疫性肝病相关抗体asma的试剂盒及其检测方法
CN102955030A (zh) * 2012-06-11 2013-03-06 郑州安图绿科生物工程有限公司 检测自身免疫性肝病相关抗体ana的试剂盒及其检测方法
CN102707055A (zh) * 2012-06-11 2012-10-03 郑州安图绿科生物工程有限公司 一种联合或单独检测自身免疫性肝病相关抗体的试剂盒及其检测方法
CN102955027A (zh) * 2012-06-11 2013-03-06 郑州安图绿科生物工程有限公司 检测自身免疫性肝病相关抗体抗lc-1抗体的试剂盒及其检测方法
GB201507719D0 (en) * 2015-05-06 2015-06-17 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides and scaffolds thereof for use in immunotherapy against colorectal carcinoma (CRC) and other cancers
EP3477303A1 (en) * 2017-10-27 2019-05-01 Medizinische Hochschule Hannover Method and means for diagnosing autoimmune hepatitis using autoantibody markers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5106726A (en) * 1990-02-16 1992-04-21 United Biomedical, Inc. Synthetic peptides specific for the detection of antibodies to HCV

Also Published As

Publication number Publication date
FR2677653A1 (fr) 1992-12-18
JP3284240B2 (ja) 2002-05-20
ATE180512T1 (de) 1999-06-15
WO1992022656A1 (fr) 1992-12-23
CA2111672A1 (en) 1992-12-23
DE69229269D1 (de) 1999-07-01
DE69229269T2 (de) 1999-11-11
FR2677653B1 (es) 1995-04-14
JPH06510663A (ja) 1994-12-01
EP0589993B1 (fr) 1999-05-26
EP0589993A1 (fr) 1994-04-06
US5830667A (en) 1998-11-03

Similar Documents

Publication Publication Date Title
ES2133320T3 (es) Fragmentos peptidicos procedentes del citocromo humano p450 iid6, anticuerpos antifragmentos peptidicos y sus aplicaciones en el diagnostico en la hepatitis autoinmune.
ES2156420T3 (es) Un dispositivo para transportar un vaso sanguineo artificial a su organo diana.
ES2079638T3 (es) Anticuerpos humanizados.
ES2124919T3 (es) Instrumento endodontico de flexibilidad predeterminada.
ATE233524T1 (de) Medizinische bandage
IT1210364B (it) Bisturi chirurgico del tipo criogenico ad ultrasuoni.
ES2158340T3 (es) Analogos peptidicos ciclicos de la somatostatina.
DK455384A (da) Middel og produkt til diagnose og terapi af tumorer samt til behandlingen af svaekkelser af celle- og humoral-immunforsvar
HK1035662A1 (en) Diagnosis, prevention and treatment of ulcerative colitis, and clinical subtypes thereof, using microbial uc panca antigens
DE69433506D1 (de) Medizinische, thermoplastische elastomere enthaltende ballone
ES2085410T3 (es) Empleo de pares de peptidos con una afinidad reciproca extremadamente elevada en el sector del diagnostico in vitro.
ES2065863T1 (es) Ensayo del virus de la hepatitis c.
ES2038571T1 (es) Procedimiento de preparacion de anticuerpos monoclonales especificos de las interleucinas 1alfa y 1beta.
ES2159192T3 (es) Dispositivo que representa el modelo de un ser vivo.
ES2053712T3 (es) Un antigeno proteico reactivo y fragmentos del mismo.
JPS5174754A (es)
FR2395591A1 (fr) Tube a rayons cathodiques du type a masque d'ombre
DE59503213D1 (de) Chirurgisches instrument
FR2482455B3 (es)
FR1222961A (fr) Appareil irrigateur pour explorations intestinales aux rayons chi à l'aide de préparations à contraste
DE3485965D1 (de) Monoklonaler antikoerper mit spezifitaet gegen nur einen typ eines isozyms der schweren kette des menschlichen herzmyosins.
MX9302501A (es) Composiciones radiograficas de contraste, y metodos para su uso en la visualizacion del conducto intestinal
ES258942U (es) Junta para piezas tubulares de aparatos para el cuidado del suelo
BE616890A (fr) Perfectionnements apportés aux mécanismes destinés à fournir les positions successives d'un fauteuil inclinable du type à mouvements multiples.
ES2162904T3 (es) Prensaestopas con montaje elastico de juntas de estanqueidad.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 589993

Country of ref document: ES