ES2123517T3 - Metodo de preparacion de ciertas pirano(3',4':6,7)indolizino(1,2-b)quinolinonas. - Google Patents

Metodo de preparacion de ciertas pirano(3',4':6,7)indolizino(1,2-b)quinolinonas.

Info

Publication number
ES2123517T3
ES2123517T3 ES91917720T ES91917720T ES2123517T3 ES 2123517 T3 ES2123517 T3 ES 2123517T3 ES 91917720 T ES91917720 T ES 91917720T ES 91917720 T ES91917720 T ES 91917720T ES 2123517 T3 ES2123517 T3 ES 2123517T3
Authority
ES
Spain
Prior art keywords
indolizino
quinolinonas
preparation
pyrano
certain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91917720T
Other languages
English (en)
Inventor
Joseph Marian Fortunak
Mark Mellinger
Jeffery Lee Wood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Application granted granted Critical
Publication of ES2123517T3 publication Critical patent/ES2123517T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Indole Compounds (AREA)

Abstract

SE PRESENTA UN METODO PARA FABRICAR 8-METIL-7-(1OXOPROPIL)INDOLICINO[1,2-B]QUINOLINA-9(11H)-ONAS A PARTIR DE 4ETIL-4-HIDROXIDO-1H-PIRANO[3'',4'':6,7]INDOLICINO[1,2-B]QUINOLIN3,14(4H, 12H)-DIONAS.
ES91917720T 1990-09-28 1991-09-23 Metodo de preparacion de ciertas pirano(3',4':6,7)indolizino(1,2-b)quinolinonas. Expired - Lifetime ES2123517T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/589,848 US5155225A (en) 1990-09-28 1990-09-28 Method for making certain pyrano[3',4':6,7]indolizino-[1,2-B]quinolinones

Publications (1)

Publication Number Publication Date
ES2123517T3 true ES2123517T3 (es) 1999-01-16

Family

ID=24359810

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91917720T Expired - Lifetime ES2123517T3 (es) 1990-09-28 1991-09-23 Metodo de preparacion de ciertas pirano(3',4':6,7)indolizino(1,2-b)quinolinonas.

Country Status (13)

Country Link
US (1) US5155225A (es)
EP (1) EP0550621B1 (es)
JP (1) JP2534000B2 (es)
KR (1) KR100192754B1 (es)
AT (1) ATE173261T1 (es)
AU (1) AU653173B2 (es)
CA (1) CA2090966A1 (es)
DE (1) DE69130481T2 (es)
DK (1) DK0550621T3 (es)
ES (1) ES2123517T3 (es)
GR (1) GR3029356T3 (es)
HK (1) HK1012382A1 (es)
WO (1) WO1992006095A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5552154A (en) * 1989-11-06 1996-09-03 The Stehlin Foundation For Cancer Research Method for treating cancer with water-insoluble s-camptothecin of the closed lactone ring form and derivatives thereof
US5883255A (en) * 1990-10-31 1999-03-16 Smithkline Beecham Corporation Substituted indolizino 1,2-b!quinolinones
US6080751A (en) * 1992-01-14 2000-06-27 The Stehlin Foundation For Cancer Research Method for treating pancreatic cancer in humans with water-insoluble S-camptothecin of the closed lactone ring form and derivatives thereof
EP0637960A4 (en) * 1992-04-17 1995-06-07 Smithkline Beecham Corp INDOLIZINO 1,2-b] SUBSTITUTED QUINOLINONES.
ZA936580B (en) * 1992-09-08 1994-08-01 Smithkline Beecham Corp Process for preparing certain pyrrolo (3 4-b)quinolines certain 1H-pyrano(3' 4':6,7)indolizino(1 2-b)quinolin-3 14(4H 12H)-diones and certain 8-methyl-7-(oxopropyl)-idolizino(1 2-b)quinolin-9(11H)-ones
CA2223484A1 (en) * 1995-06-07 1996-12-19 Thomas Jefferson University Anti-fungal agents and methods of identifying and using the same
KR20080068052A (ko) * 2005-10-10 2008-07-22 씨아이피엘에이 엘티디. 신규의 결정형

Also Published As

Publication number Publication date
US5155225A (en) 1992-10-13
EP0550621A4 (es) 1995-01-11
CA2090966A1 (en) 1992-03-29
EP0550621A1 (en) 1993-07-14
ATE173261T1 (de) 1998-11-15
DE69130481T2 (de) 1999-06-24
WO1992006095A1 (en) 1992-04-16
GR3029356T3 (en) 1999-05-28
AU653173B2 (en) 1994-09-22
DK0550621T3 (da) 1999-07-26
JP2534000B2 (ja) 1996-09-11
JPH06501259A (ja) 1994-02-10
DE69130481D1 (de) 1998-12-17
AU8639891A (en) 1992-04-28
HK1012382A1 (en) 1999-07-30
KR100192754B1 (ko) 1999-06-15
EP0550621B1 (en) 1998-11-11

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