ES2121479T3 - Solucion estabilizadora para proteinas y peptidos. - Google Patents
Solucion estabilizadora para proteinas y peptidos.Info
- Publication number
- ES2121479T3 ES2121479T3 ES96907187T ES96907187T ES2121479T3 ES 2121479 T3 ES2121479 T3 ES 2121479T3 ES 96907187 T ES96907187 T ES 96907187T ES 96907187 T ES96907187 T ES 96907187T ES 2121479 T3 ES2121479 T3 ES 2121479T3
- Authority
- ES
- Spain
- Prior art keywords
- proteins
- peptides
- controls
- stabilizing solution
- stabilizing proteins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4712—Muscle proteins, e.g. myosin, actin, protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Pathology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE DESCRIBEN COMPOSICIONES PARA ESTABILIZAR PROTEINAS Y FRAGMENTOS DE PROTEINAS. LA COMPOSICION CONTIENE TAMPON, SAL, AGENTES REDUCTORES, Y PROTEINAS ESTABILIZADORAS. DICHA COMPOSICION SE PUEDE USAR PARA PREPARAR CALIBRADORES DE DIAGNOSTICO O CONTROLES, ALTAMENTE ESTABLES, Y ES PARTICULARMENTE UTIL PARA CALIBRADORES O CONTROLES PARA MARCADORES CARDIACOS, COMO TROPONINA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/400,158 US6165981A (en) | 1995-03-07 | 1995-03-07 | Stabilizing solutions for proteins and peptides |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2121479T3 true ES2121479T3 (es) | 1998-11-16 |
Family
ID=23582452
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96907187T Expired - Lifetime ES2121479T3 (es) | 1995-03-07 | 1996-03-06 | Solucion estabilizadora para proteinas y peptidos. |
Country Status (8)
Country | Link |
---|---|
US (1) | US6165981A (es) |
EP (1) | EP0759074B1 (es) |
JP (1) | JP3740644B2 (es) |
AU (1) | AU698790B2 (es) |
CA (1) | CA2189737A1 (es) |
DE (1) | DE69600407T2 (es) |
ES (1) | ES2121479T3 (es) |
WO (1) | WO1996027661A1 (es) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6627404B1 (en) * | 1995-04-18 | 2003-09-30 | Biosite, Inc. | Methods for improving the recovery of troponin I and T in membranes, filters and vessels |
US7006874B2 (en) * | 1996-01-05 | 2006-02-28 | Thermage, Inc. | Treatment apparatus with electromagnetic energy delivery device and non-volatile memory |
EP0827750A3 (en) * | 1996-08-23 | 2002-11-20 | Eli Lilly And Company | Obesity protein formulations |
US6072040A (en) * | 1996-10-15 | 2000-06-06 | Medical Analysis Systems, Inc. | Stabilized conjugates of uncomplexed subunits of multimeric proteins |
FR2756827B1 (fr) * | 1996-12-05 | 1999-01-29 | Pasteur Sanofi Diagnostics | Composes synthetiques biepitopiques utilisables comme etalons dans les dosages biologiques de la troponine i |
US6156521A (en) * | 1997-12-19 | 2000-12-05 | Biosite Diagnostics, Inc. | Methods for the recovery and measurement of troponin complexes |
CA2277282A1 (en) * | 1997-01-17 | 1998-07-23 | Eli Lilly And Company | Obesity protein formulations |
US6274553B1 (en) * | 1997-01-20 | 2001-08-14 | Japan Energy Corporation | Method for stabilizing peptides and freeze-dried medicinal compositions containing peptides obtained by using the method |
WO1998041222A1 (en) * | 1997-03-20 | 1998-09-24 | Eli Lilly And Company | Obesity protein formulations |
US6248869B1 (en) | 1997-05-29 | 2001-06-19 | Medical Analysis Systems, Inc. | Troponin I forms and use of the same |
EP1000140A1 (en) * | 1997-06-13 | 2000-05-17 | Medical Analysis Systems, Inc. (MAS) | Stabilized compositions of cardiac markers |
AU6117099A (en) * | 1998-10-21 | 2000-05-08 | Spectral Diagnostics Inc. | Cardiac troponin i polypeptide fragments and uses in diagnostics |
DE19930676B4 (de) | 1999-07-02 | 2006-01-19 | Sanofi-Aventis Deutschland Gmbh | Verfahren zur Stabilisierung von Insulin, Insulinderivaten und/oder deren Vorläufer in komplexen Mischungen bei deren Lagerung in wäßrigen Lösungsmitteln |
FR2797689B1 (fr) * | 1999-08-16 | 2003-06-27 | Pasteur Sanofi Diagnostics | Utilisation de composes synthetiques pour des immunodosages |
US7078486B2 (en) | 1999-12-10 | 2006-07-18 | Spectral Diagnostics, Inc. | Single-chain polypeptides comprising troponin I and troponin C |
US7754686B2 (en) * | 2000-08-31 | 2010-07-13 | Novartis Vaccines And Diagnostics, Inc. | Stabilized FGF formulations containing reducing agents |
US6962700B1 (en) * | 2000-09-13 | 2005-11-08 | Atopix Pharmaceuticals Corporation | Method of manufacturing immune globulin |
US6538104B2 (en) | 2001-04-27 | 2003-03-25 | Medical Analysis Systems, Inc. | Stabilization of cardiac troponin I subunits and complexes |
US6927062B2 (en) * | 2002-11-25 | 2005-08-09 | Agdia, Inc. | Controls and standards for assays and method for manufacture thereof |
US7291501B2 (en) * | 2003-07-16 | 2007-11-06 | Abbott Laboratories | Stable compositions for measuring human natriuretic peptides |
US7445933B2 (en) * | 2003-07-16 | 2008-11-04 | Abbott Laboratories, Inc. | Stable calibrators or controls for measuring human natriuretic peptides |
US20050136542A1 (en) * | 2003-12-19 | 2005-06-23 | Beckman Coulter, Inc. | Stabilized liquid reference solutions |
ATE463509T1 (de) * | 2005-04-28 | 2010-04-15 | Abbott Lab | Stabilisierung von herz-troponin |
AU2007234612B2 (en) | 2006-12-14 | 2013-06-27 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein stabilization formulations |
US7678764B2 (en) * | 2007-06-29 | 2010-03-16 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein formulations for use at elevated temperatures |
EP2187932B1 (en) * | 2007-08-07 | 2015-01-28 | DePuy Synthes Products, LLC | Protein formulations comprising gdf-5 in aqueous acidic solution |
CA2720845A1 (en) | 2008-04-14 | 2009-10-22 | Advanced Technologies And Regenerative Medicine, Llc | Liquid buffered gdf-5 formulations |
US20110306148A1 (en) | 2010-06-14 | 2011-12-15 | Siemens Healthcare Diagnostics Inc. | Composition for use as an assay reagent |
CN107167613B (zh) * | 2017-06-22 | 2018-10-02 | 深圳清华大学研究院 | 用于等离子体金芯片的蛋白点样缓冲液 |
CN109254153B (zh) * | 2018-08-27 | 2021-10-12 | 广东菲鹏生物有限公司 | 肌红蛋白的抗氧化剂及其应用 |
US20210212311A1 (en) * | 2018-09-28 | 2021-07-15 | Siemens Healthcare Diagnostics Inc. | Storage solution compositions for the stabilization of purified müllerian inhibiting substance (mis) and methods of use and production related thereto |
CN109725148B (zh) * | 2018-12-30 | 2022-05-03 | 广东环凯微生物科技有限公司 | 一种免疫磁珠保存液 |
AU2021260878A1 (en) | 2020-04-20 | 2022-11-17 | Vestaron Corporation | Proteolytically stable U1-agatoxin-Ta1b variant polypeptides for pest control |
TW202205956A (zh) | 2020-05-01 | 2022-02-16 | 美商韋斯塔隆公司 | 殺蟲組合 |
CN114324882B (zh) * | 2020-10-12 | 2022-12-27 | 广东菲鹏生物有限公司 | 蛋白稳定剂及其应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4931385A (en) * | 1985-06-24 | 1990-06-05 | Hygeia Sciences, Incorporated | Enzyme immunoassays and immunologic reagents |
US5217890A (en) * | 1991-08-20 | 1993-06-08 | Eastman Kodak Company | Stabilized composition containing creatine kinase and protein having blocked sulfhydryl groups |
FR2701954B1 (fr) * | 1993-02-23 | 1995-07-07 | Pasteur Sanofi Diagnostics | Composition stabilisée de troponine pour immunoessais et procédé de stabilisation de troponine pour immunoessais. |
JPH09503050A (ja) * | 1993-05-17 | 1997-03-25 | フォートロン バイオサイエンス インク. | 心臓トロポニン▲i▼のアッセイ |
-
1995
- 1995-03-07 US US08/400,158 patent/US6165981A/en not_active Expired - Lifetime
-
1996
- 1996-03-06 ES ES96907187T patent/ES2121479T3/es not_active Expired - Lifetime
- 1996-03-06 AU AU50929/96A patent/AU698790B2/en not_active Ceased
- 1996-03-06 DE DE69600407T patent/DE69600407T2/de not_active Expired - Lifetime
- 1996-03-06 EP EP96907187A patent/EP0759074B1/en not_active Expired - Lifetime
- 1996-03-06 CA CA002189737A patent/CA2189737A1/en not_active Abandoned
- 1996-03-06 JP JP52702396A patent/JP3740644B2/ja not_active Expired - Fee Related
- 1996-03-06 WO PCT/US1996/003034 patent/WO1996027661A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
AU698790B2 (en) | 1998-11-05 |
JPH10500704A (ja) | 1998-01-20 |
EP0759074B1 (en) | 1998-07-08 |
WO1996027661A1 (en) | 1996-09-12 |
DE69600407D1 (de) | 1998-08-13 |
AU5092996A (en) | 1996-09-23 |
JP3740644B2 (ja) | 2006-02-01 |
CA2189737A1 (en) | 1996-09-12 |
DE69600407T2 (de) | 1999-04-29 |
EP0759074A1 (en) | 1997-02-26 |
US6165981A (en) | 2000-12-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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