ES2119874T3 - Nuevos derivados de elipticina, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. - Google Patents
Nuevos derivados de elipticina, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.Info
- Publication number
- ES2119874T3 ES2119874T3 ES93402395T ES93402395T ES2119874T3 ES 2119874 T3 ES2119874 T3 ES 2119874T3 ES 93402395 T ES93402395 T ES 93402395T ES 93402395 T ES93402395 T ES 93402395T ES 2119874 T3 ES2119874 T3 ES 2119874T3
- Authority
- ES
- Spain
- Prior art keywords
- elipticina
- contain
- pharmaceutical compositions
- preparation procedure
- new derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen(.) Chemical compound [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Indole Compounds (AREA)
Abstract
COMPUESTOS DE FORMULA GENERAL (I), EN LA CUAL: R1 REPRESENTA LA AGRUPACION , EN LA CUAL, N = 1-6; R, R'' Y R6 = H, ALQUILO EVENTUALMENTE SUSTITUIDO POR HO, O BIEN R Y R'' FORMAN JUNTO CON EL ATOMO DE NITROGENO UN HETEROCICLO, O BIEN R Y R6 FORMAN UN HETEROCICLO; R2 = ALQUILO; R3, R4, R5 = H O ALQUILO CON ACTIVIDAD ANTITUMORAL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9211672A FR2696465B1 (fr) | 1992-10-02 | 1992-10-02 | Nouveaux dérivés d'ellipticine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2119874T3 true ES2119874T3 (es) | 1998-10-16 |
Family
ID=9434061
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93402395T Expired - Lifetime ES2119874T3 (es) | 1992-10-02 | 1993-10-01 | Nuevos derivados de elipticina, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. |
Country Status (15)
Country | Link |
---|---|
US (2) | US5407940A (es) |
EP (1) | EP0591058B1 (es) |
JP (1) | JP2529082B2 (es) |
AT (1) | ATE166875T1 (es) |
AU (1) | AU660853B2 (es) |
CA (1) | CA2107485C (es) |
CY (1) | CY2140B1 (es) |
DE (1) | DE69318920T2 (es) |
DK (1) | DK0591058T3 (es) |
ES (1) | ES2119874T3 (es) |
FR (1) | FR2696465B1 (es) |
GR (1) | GR3027772T3 (es) |
HK (1) | HK1010051A1 (es) |
NZ (1) | NZ248841A (es) |
ZA (1) | ZA937308B (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU666416B2 (en) * | 1993-01-29 | 1996-02-08 | Tanabe Seiyaku Co., Ltd. | Ellipticine derivative and process for preparing the same |
FR2757859B1 (fr) * | 1996-12-30 | 1999-01-29 | Adir | Nouveaux derives d'ellipticine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2757858B1 (fr) * | 1996-12-30 | 1999-01-29 | Adir | Nouveaux derives d'ellipticine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2767132B1 (fr) * | 1997-08-06 | 1999-09-10 | Adir | Nouveaux composes de bis pyrido [4,3-b] carbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
JP2002522435A (ja) * | 1998-08-03 | 2002-07-23 | アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ | (1h)−ベンゾ[c]キノリン−3−オン誘導体の合成方法 |
US6231894B1 (en) | 1999-10-21 | 2001-05-15 | Duke University | Treatments based on discovery that nitric oxide synthase is a paraquat diaphorase |
US6624317B1 (en) | 2000-09-25 | 2003-09-23 | The University Of North Carolina At Chapel Hill | Taxoid conjugates as antimitotic and antitumor agents |
US6677450B2 (en) | 2000-10-06 | 2004-01-13 | Bristol-Myers Squibb Company | Topoisomerase inhibitors |
US6653290B2 (en) * | 2000-10-06 | 2003-11-25 | Bristol-Myers Squibb Company | Tumor proliferation inhibitors |
US6610727B2 (en) | 2000-10-06 | 2003-08-26 | Bristol-Myers Squibb Company | Anhydro sugar derivatives of indolocarbazoles |
WO2002060867A2 (en) * | 2001-01-29 | 2002-08-08 | Insight Strategy And Marketing Ltd | Carbazole derivatives and their uses as heparanase inhibitors |
US6855698B2 (en) | 2001-03-22 | 2005-02-15 | Bristol-Myers Squibb Company | Topoisomerase I selective cytotoxic sugar derivatives of indolopyrrolocarbazoles |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU666416B2 (en) * | 1993-01-29 | 1996-02-08 | Tanabe Seiyaku Co., Ltd. | Ellipticine derivative and process for preparing the same |
-
1992
- 1992-10-02 FR FR9211672A patent/FR2696465B1/fr not_active Expired - Fee Related
-
1993
- 1993-10-01 NZ NZ248841A patent/NZ248841A/en unknown
- 1993-10-01 US US08/130,627 patent/US5407940A/en not_active Expired - Fee Related
- 1993-10-01 ZA ZA937308A patent/ZA937308B/xx unknown
- 1993-10-01 DE DE69318920T patent/DE69318920T2/de not_active Expired - Fee Related
- 1993-10-01 AU AU48727/93A patent/AU660853B2/en not_active Ceased
- 1993-10-01 CA CA002107485A patent/CA2107485C/fr not_active Expired - Fee Related
- 1993-10-01 EP EP93402395A patent/EP0591058B1/fr not_active Expired - Lifetime
- 1993-10-01 DK DK93402395T patent/DK0591058T3/da active
- 1993-10-01 AT AT93402395T patent/ATE166875T1/de not_active IP Right Cessation
- 1993-10-01 ES ES93402395T patent/ES2119874T3/es not_active Expired - Lifetime
- 1993-10-01 JP JP5247081A patent/JP2529082B2/ja not_active Expired - Fee Related
-
1994
- 1994-07-21 US US08/278,269 patent/US5498611A/en not_active Expired - Fee Related
-
1998
- 1998-08-28 GR GR980401951T patent/GR3027772T3/el unknown
- 1998-09-16 HK HK98110653A patent/HK1010051A1/xx not_active IP Right Cessation
-
1999
- 1999-11-19 CY CY9900036A patent/CY2140B1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DK0591058T3 (da) | 1999-03-22 |
CA2107485A1 (fr) | 1994-04-03 |
JPH06211852A (ja) | 1994-08-02 |
ZA937308B (en) | 1994-04-22 |
DE69318920T2 (de) | 1999-01-21 |
FR2696465B1 (fr) | 1994-12-23 |
CA2107485C (fr) | 2001-02-27 |
DE69318920D1 (de) | 1998-07-09 |
NZ248841A (en) | 1995-02-24 |
AU4872793A (en) | 1994-04-14 |
GR3027772T3 (en) | 1998-11-30 |
AU660853B2 (en) | 1995-07-06 |
HK1010051A1 (en) | 1999-06-11 |
US5407940A (en) | 1995-04-18 |
EP0591058B1 (fr) | 1998-06-03 |
CY2140B1 (en) | 2002-06-21 |
US5498611A (en) | 1996-03-12 |
EP0591058A1 (fr) | 1994-04-06 |
FR2696465A1 (fr) | 1994-04-08 |
ATE166875T1 (de) | 1998-06-15 |
JP2529082B2 (ja) | 1996-08-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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