ES2109859B1 - NEW ARILPROPIONIC DERIVATIVES WITH ANALGESIC ACTION AND PROCEDURE FOR THEIR OBTAINING. - Google Patents

NEW ARILPROPIONIC DERIVATIVES WITH ANALGESIC ACTION AND PROCEDURE FOR THEIR OBTAINING.

Info

Publication number
ES2109859B1
ES2109859B1 ES9402407A ES9402407A ES2109859B1 ES 2109859 B1 ES2109859 B1 ES 2109859B1 ES 9402407 A ES9402407 A ES 9402407A ES 9402407 A ES9402407 A ES 9402407A ES 2109859 B1 ES2109859 B1 ES 2109859B1
Authority
ES
Spain
Prior art keywords
arilpropionic
derivatives
procedure
new
obtaining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9402407A
Other languages
Spanish (es)
Other versions
ES2109859A1 (en
Inventor
Casellas David Mauleon
Perez M Luisa Garcia
Torro M Desamparados Fos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Menarini SA
Original Assignee
Laboratorios Menarini SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Menarini SA filed Critical Laboratorios Menarini SA
Priority to ES9402407A priority Critical patent/ES2109859B1/en
Priority to PCT/EP1995/004567 priority patent/WO1996016017A1/en
Priority to AU41746/96A priority patent/AU4174696A/en
Publication of ES2109859A1 publication Critical patent/ES2109859A1/en
Application granted granted Critical
Publication of ES2109859B1 publication Critical patent/ES2109859B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part

Abstract

NUEVOS DERIVADOS ARILPROPIONICOS CON ACCION ANALGESICA Y PROCEDIMIENTO PARA SU OBTENCION. LA PRESENTE INVENCION SE REFIERE A NUEVOS DERIVADOS ARILPROPIONICOS, CONCRETAMENTE LAS SALES CON IONES METALICOS DEL ACIDO (+)-(S)-2-(3-BENZOILFENIL) PROPIONICO DE FORMULA I, FORMULA DONDE M+ ES LA CANTIDAD ESTEQUIOMETRICA REQUERIDA DE LOS CATIONES CORRESPONDIENTES A SODIO, POTASIO, CALCIO, MAGNESIO, ZINC O ALUMINIO. EL PROCEDIMIENTO PARA SU PREPARACION COMPRENDE LA REACCION DEL ACIDO (+)-(S)-2-(3-BENZOILFENIL)PROPIONICO (II) O UNA SAL DEL MISMO CON UNA SAL METALICA. DICHOS COMPUESTOS EXHIBEN UNA ELEVADA ACCION COMO ANALGESICOS Y ANTIINFLAMATORIOS EN TERAPIA HUMANA.NEW ARILPROPIONIC DERIVATIVES WITH ANALGESIC ACTION AND PROCEDURE FOR THEIR OBTAINING. THE PRESENT INVENTION REFERS TO NEW ARILPROPIONIC DERIVATIVES, SPECIFICALLY THE SALTS WITH METALLIC IONS OF THE ACID (+) - (S) -2- (3-BENZOILFENIL) PROPIONICO OF FORMULA I, THE QUANTITY OF THE EASTQUIERE CORRIDANCE SODIUM, POTASSIUM, CALCIUM, MAGNESIUM, ZINC OR ALUMINUM. THE PROCEDURE FOR ITS PREPARATION INCLUDES THE REACTION OF THE ACID (+) - (S) -2- (3-BENZOILFENIL) PROPIONICO (II) OR A SALT OF THE SAME WITH A METALLIC SALT. SUCH COMPOUNDS EXHIBIT A HIGH ACTION AS ANALGESICS AND ANTI-INFLAMMATORIES IN HUMAN THERAPY.

ES9402407A 1994-11-23 1994-11-23 NEW ARILPROPIONIC DERIVATIVES WITH ANALGESIC ACTION AND PROCEDURE FOR THEIR OBTAINING. Expired - Fee Related ES2109859B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ES9402407A ES2109859B1 (en) 1994-11-23 1994-11-23 NEW ARILPROPIONIC DERIVATIVES WITH ANALGESIC ACTION AND PROCEDURE FOR THEIR OBTAINING.
PCT/EP1995/004567 WO1996016017A1 (en) 1994-11-23 1995-11-20 Novel arylpropionic derivatives with analgesic action and the process for the preparation thereof
AU41746/96A AU4174696A (en) 1994-11-23 1995-11-20 Novel arylpropionic derivatives with analgesic action and the process for the preparation thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9402407A ES2109859B1 (en) 1994-11-23 1994-11-23 NEW ARILPROPIONIC DERIVATIVES WITH ANALGESIC ACTION AND PROCEDURE FOR THEIR OBTAINING.

Publications (2)

Publication Number Publication Date
ES2109859A1 ES2109859A1 (en) 1998-01-16
ES2109859B1 true ES2109859B1 (en) 1998-08-16

Family

ID=8288068

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9402407A Expired - Fee Related ES2109859B1 (en) 1994-11-23 1994-11-23 NEW ARILPROPIONIC DERIVATIVES WITH ANALGESIC ACTION AND PROCEDURE FOR THEIR OBTAINING.

Country Status (3)

Country Link
AU (1) AU4174696A (en)
ES (1) ES2109859B1 (en)
WO (1) WO1996016017A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7090859B2 (en) * 2002-12-13 2006-08-15 Ronald Thomas Haas Ketoprofen compositions and methods of making them

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1546478A (en) * 1967-01-27 1968-11-22 Rhone Poulenc Sa New derivatives of 3-benzoylphenylacetic acid and their preparation
FR6444M (en) * 1967-04-24 1968-11-12
IT1175941B (en) * 1984-02-16 1987-08-12 Stabil Bioterapico Farmachim MONO, BI AND TRI-SUBSTITUTED ALUMINUM SALTS OF ARYL-ALCANOIC ACIDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
AU4174696A (en) 1996-06-17
ES2109859A1 (en) 1998-01-16
WO1996016017A1 (en) 1996-05-30

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