ES2109005T3 - Procedimiento de sintesis de acidos nucleicos sobre soporte solido y compuestos utiles en particular como soporte solido en dicho procedimiento. - Google Patents
Procedimiento de sintesis de acidos nucleicos sobre soporte solido y compuestos utiles en particular como soporte solido en dicho procedimiento.Info
- Publication number
- ES2109005T3 ES2109005T3 ES94921699T ES94921699T ES2109005T3 ES 2109005 T3 ES2109005 T3 ES 2109005T3 ES 94921699 T ES94921699 T ES 94921699T ES 94921699 T ES94921699 T ES 94921699T ES 2109005 T3 ES2109005 T3 ES 2109005T3
- Authority
- ES
- Spain
- Prior art keywords
- solid support
- procedure
- nucleic acid
- acid synthesis
- epoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Saccharide Compounds (AREA)
- Catalysts (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A UN PROCESO DE SINTESIS DE ACIDOS NUCLEICOS EN FASE SOLIDA, CARACTERIZADO EN QUE SE UTILIZA COMO SOPORTE SOLIDO UN POLIMERO MINERAL U ORGANICO CONECTADO POR UN RADICAL HIDROCARBONO DIVALENTE A UN GRUPO EPOXIDO O UN GRUPO DEL TIPO GLICOL, CONSISTIENDO ESTE ULTIMO EN DOS CARBONOS SATURADOS ADYACENTES SOBRE LOS QUE SE ENCUENTRAN SUSTITUIDOS UN GRUPO OH Y UN GRUPO NUCLEOFILO. LA PRESENTE INVENCION SE REFIERE TAMBIEN A COMPUESTOS QUE COMPRENDEN UN GRUPO EPOXIDO O UN GRUPO DEL TIPO GLICOL TAL COMO SE DEFINE ARRIBA UTIL PARTICULARMENTE COMO SOPORTE SOLIDO EN UN PROCESO DE SINTESIS DE ACIDOS NUCLEICOS SOBRE SOPORTE SOLIDO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9308498A FR2707296B1 (fr) | 1993-07-09 | 1993-07-09 | Procédé de synthèse d'acides nucléiques sur support solide et composés utiles notamment comme support solide dans ledit procédé. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2109005T3 true ES2109005T3 (es) | 1998-01-01 |
Family
ID=9449129
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94921699T Expired - Lifetime ES2109005T3 (es) | 1993-07-09 | 1994-07-07 | Procedimiento de sintesis de acidos nucleicos sobre soporte solido y compuestos utiles en particular como soporte solido en dicho procedimiento. |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0707592B1 (es) |
JP (1) | JPH08512306A (es) |
KR (1) | KR960703937A (es) |
AT (1) | ATE157668T1 (es) |
AU (1) | AU696421B2 (es) |
CA (1) | CA2166765A1 (es) |
DE (1) | DE69405396T2 (es) |
DK (1) | DK0707592T3 (es) |
ES (1) | ES2109005T3 (es) |
FR (1) | FR2707296B1 (es) |
GR (1) | GR3025420T3 (es) |
HK (1) | HK1002731A1 (es) |
TW (1) | TW397839B (es) |
WO (1) | WO1995001987A1 (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2714061B1 (fr) * | 1993-12-16 | 1996-03-08 | Genset Sa | Procédé de préparation de polynucléotides sur support solide et appareil permettant sa mise en Óoeuvre. |
US5869696A (en) * | 1996-04-22 | 1999-02-09 | Beckman Instruments, Inc. | Universal solid supports and methods for their use |
US6590092B1 (en) | 1998-05-19 | 2003-07-08 | Nam Q. Ngo | Process for preparing a “universal support” and the reagents used for generating such support |
DE69814097T2 (de) * | 1998-12-02 | 2004-04-08 | Council Of Scientific And Industrial Research | Universale Polymere Träger zur Synthese von Oligonukleotiden |
WO2000047771A2 (en) | 1999-02-12 | 2000-08-17 | Genset | Biallelic markers derived from genomic regions carrying genes involved in arachidonic acid metabolism |
AU2942100A (en) * | 1999-03-11 | 2000-09-28 | Kuraray Co., Ltd. | Vitamin d derivatives and process for the preparation thereof |
EP1132739B1 (en) * | 2000-05-16 | 2001-09-26 | BioChip Technologies GmbH | Linker system for activating surfaces for bioconjugation and methods for their use |
US7211654B2 (en) | 2001-03-14 | 2007-05-01 | Regents Of The University Of Michigan | Linkers and co-coupling agents for optimization of oligonucleotide synthesis and purification on solid supports |
EP1925672A1 (en) | 2001-06-22 | 2008-05-28 | Syngeta Participations AG | Abiotic stress responsive polynucleotides and polypeptides |
US7858297B2 (en) | 2001-12-18 | 2010-12-28 | Centre National De La Recherche Scientifique Cnrs | Chemokine-binding protein and methods of use |
ES2337989T3 (es) | 2001-12-18 | 2010-05-03 | Endocube Sas | Nuevas proteinas asociadas a la muerte de la familia thap y rutas par4 relacionadas implicadas en el control de la apoptosis. |
AU2003214558A1 (en) | 2002-03-13 | 2003-09-22 | Bayer Cropscience Sa | Mutagenesis of aspergillus fungi and identification of genes essential for growth |
FR2900415B1 (fr) | 2006-04-28 | 2010-08-13 | Agronomique Inst Nat Rech | Systeme genetique pour le controle du developpement du type floral d'une plante dicotyledone, et mise en oeuvre dans les procedes de detection et de selection |
FR2954349A1 (fr) | 2009-12-22 | 2011-06-24 | Agronomique Inst Nat Rech | Sulfatase modifiant selectivement les glycosaminoglycanes |
EP4050109A1 (en) | 2010-08-18 | 2022-08-31 | Fred Hutchinson Cancer Center | Agents for use in treating facioscapulohumeral dystrophy (fshd) |
US10781175B2 (en) | 2016-07-15 | 2020-09-22 | Am Chemicals Llc | Solid supports and phosphoramidite building blocks for oligonucleotide conjugates |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0155950B1 (en) * | 1983-09-02 | 1990-01-17 | Molecular Biosystems, Inc. | Oligonucleotide polymeric support system |
US4739044A (en) * | 1985-06-13 | 1988-04-19 | Amgen | Method for derivitization of polynucleotides |
WO1991000868A1 (en) * | 1989-07-07 | 1991-01-24 | National Research Development Corporation | Immobilised polynucleotides |
EP0504321B1 (en) * | 1989-12-04 | 1997-05-07 | Microprobe Corporation | Enhanced capture of target nucleic acid by the use of oligonucleotides covalently attached to polymers |
DK0592434T3 (da) * | 1990-10-26 | 1999-06-21 | Genta Inc | Forbedret fremgangsmåde til syntese af oligomerer |
EP0554407A1 (en) * | 1990-10-26 | 1993-08-11 | Genta Incorporated | Non-aromatic organic polymeric reagents for solid phase synthesis of oligomers |
-
1993
- 1993-07-09 FR FR9308498A patent/FR2707296B1/fr not_active Expired - Fee Related
-
1994
- 1994-07-07 ES ES94921699T patent/ES2109005T3/es not_active Expired - Lifetime
- 1994-07-07 CA CA002166765A patent/CA2166765A1/fr not_active Abandoned
- 1994-07-07 AU AU72309/94A patent/AU696421B2/en not_active Expired
- 1994-07-07 WO PCT/FR1994/000842 patent/WO1995001987A1/fr active IP Right Grant
- 1994-07-07 DK DK94921699.8T patent/DK0707592T3/da active
- 1994-07-07 JP JP7503866A patent/JPH08512306A/ja active Pending
- 1994-07-07 KR KR1019960700059A patent/KR960703937A/ko not_active Application Discontinuation
- 1994-07-07 DE DE69405396T patent/DE69405396T2/de not_active Expired - Lifetime
- 1994-07-07 EP EP94921699A patent/EP0707592B1/fr not_active Expired - Lifetime
- 1994-07-07 AT AT94921699T patent/ATE157668T1/de not_active IP Right Cessation
- 1994-11-18 TW TW083110699A patent/TW397839B/zh not_active IP Right Cessation
-
1997
- 1997-11-19 GR GR970403065T patent/GR3025420T3/el unknown
-
1998
- 1998-02-27 HK HK98101580A patent/HK1002731A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ATE157668T1 (de) | 1997-09-15 |
EP0707592B1 (fr) | 1997-09-03 |
JPH08512306A (ja) | 1996-12-24 |
GR3025420T3 (en) | 1998-02-27 |
KR960703937A (ko) | 1996-08-31 |
CA2166765A1 (fr) | 1995-01-19 |
WO1995001987A1 (fr) | 1995-01-19 |
TW397839B (en) | 2000-07-11 |
FR2707296B1 (fr) | 1995-09-29 |
FR2707296A1 (fr) | 1995-01-13 |
EP0707592A1 (fr) | 1996-04-24 |
DK0707592T3 (da) | 1998-03-30 |
DE69405396D1 (de) | 1997-10-09 |
AU7230994A (en) | 1995-02-06 |
AU696421B2 (en) | 1998-09-10 |
HK1002731A1 (en) | 1998-09-11 |
DE69405396T2 (de) | 1998-03-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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