ES2107460T3 - Tratamiento de la trombosis. - Google Patents

Tratamiento de la trombosis.

Info

Publication number
ES2107460T3
ES2107460T3 ES91907925T ES91907925T ES2107460T3 ES 2107460 T3 ES2107460 T3 ES 2107460T3 ES 91907925 T ES91907925 T ES 91907925T ES 91907925 T ES91907925 T ES 91907925T ES 2107460 T3 ES2107460 T3 ES 2107460T3
Authority
ES
Spain
Prior art keywords
treatment
thrombosis
platelet aggregates
amount
hementin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91907925T
Other languages
English (en)
Inventor
Roy T Sawyer
Christopher Powell-Jones
Anthony Atkinson
Asgar Electricwala
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909007879A external-priority patent/GB9007879D0/en
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Application granted granted Critical
Publication of ES2107460T3 publication Critical patent/ES2107460T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

UN METODO DE TRATAMIENTO DE SUCESOS TROMBOTICOS QUE COMPRENDE EL ADMINISTRAR UNA CANTIDAD TERAPEUTICAMENTE EFICAZ DE UNA FORMULACION FARMACEUTICA COMPRENDIENDO HEMETINA O UN MATERIAL CAPAZ DE DIVIDIRSE ENTRE LOS DOMINIOS D Y E DE LOS ENLACES FIBRINOGENOS PRESENTES EN LOS AGREGADOS PLAQUETARIOS, EN TAL CANTIDAD Y DE TAL MANERA COMO PARA DISOLVER UN COAGULO QUE PREDOMINANTEMENTE COMPRENDE, POR VOLUMEN, AGREGADOS PLAQUETARIOS.
ES91907925T 1990-04-06 1991-04-08 Tratamiento de la trombosis. Expired - Lifetime ES2107460T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909007879A GB9007879D0 (en) 1990-04-06 1990-04-06 Treatment of thrombotic events
GB909008863A GB9008863D0 (en) 1990-04-06 1990-04-20 Treatment of thrombotic events

Publications (1)

Publication Number Publication Date
ES2107460T3 true ES2107460T3 (es) 1997-12-01

Family

ID=26296911

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91907925T Expired - Lifetime ES2107460T3 (es) 1990-04-06 1991-04-08 Tratamiento de la trombosis.

Country Status (10)

Country Link
EP (1) EP0487660B1 (es)
JP (1) JP3878668B2 (es)
AT (1) ATE157121T1 (es)
AU (1) AU645804B2 (es)
CA (1) CA2058635C (es)
DE (1) DE69127346T2 (es)
DK (1) DK0487660T3 (es)
ES (1) ES2107460T3 (es)
GR (1) GR3025238T3 (es)
WO (1) WO1991015576A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9309509D0 (en) * 1993-05-07 1993-06-23 Merck Patent Gmbh Thrombin inhibitors
US7691839B2 (en) 2005-09-28 2010-04-06 Biovascular, Inc. Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation
EP2316465A1 (en) * 2009-10-15 2011-05-04 Centre National De La Recherche Scientifique Use of extract of leeches' saliva as anti-bacterial agent for the manufacture of different compositons

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4390630A (en) * 1980-10-28 1983-06-28 The Regents Of The University Of California Hementin--a fibrinolytic agent
GB8808810D0 (en) * 1988-04-14 1988-05-18 Biopharm Clinical Research Ltd Heparin-containing formulations

Also Published As

Publication number Publication date
DK0487660T3 (da) 1998-03-30
AU7690191A (en) 1991-10-30
CA2058635C (en) 2002-02-05
GR3025238T3 (en) 1998-02-27
DE69127346T2 (de) 1998-02-26
WO1991015576A1 (en) 1991-10-17
JPH05500906A (ja) 1993-02-25
ATE157121T1 (de) 1997-09-15
CA2058635A1 (en) 1991-10-07
JP3878668B2 (ja) 2007-02-07
EP0487660B1 (en) 1997-08-20
DE69127346D1 (de) 1997-09-25
EP0487660A1 (en) 1992-06-03
AU645804B2 (en) 1994-01-27

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