ES2106025T3 - Analogos de gangliosidos semisinteticos. - Google Patents

Analogos de gangliosidos semisinteticos.

Info

Publication number
ES2106025T3
ES2106025T3 ES90402139T ES90402139T ES2106025T3 ES 2106025 T3 ES2106025 T3 ES 2106025T3 ES 90402139 T ES90402139 T ES 90402139T ES 90402139 T ES90402139 T ES 90402139T ES 2106025 T3 ES2106025 T3 ES 2106025T3
Authority
ES
Spain
Prior art keywords
acil
semi
derived
groups
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90402139T
Other languages
English (en)
Inventor
Valle Francesco Della
Aurelio Romeo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fidia SpA
Original Assignee
Fidia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia SpA filed Critical Fidia SpA
Application granted granted Critical
Publication of ES2106025T3 publication Critical patent/ES2106025T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Lead Frames For Integrated Circuits (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

SE PRESENTAN N-ACIL-N,N''-DILISOGANGLIOSIDOS EN LOS QUE LOS GRUPOS ACIL SE DERIVAN DE ACIDOS ALIFATICOS INSUBSTITUIDOS QUE TIENEN ENTRE 1 Y 11 ATOMOS DE CARBONO, Y N''-ACIL-N, N''-DILISOGANGLIOSIDOS Y N, N'' CUALES LOS GRUPOS ACIL SE DERIVAN DE ACIDOS HALIFATICOS INSUBSTITUIDOS QUE TIENEN ENTRE 1 Y 24 ATOMOS DE CARBONO (CON LA EXCEPCION DE CIERTOS DERIVADOS DEL ACETIL Y DEL DIACETIL). LOS COMPUESTOS DEL INVENTO EXHIBEN UNA ACCION INHIBIDORA SOBRE LA ACTIVACION C DE LA PROTEINA KINASA Y DE ESTA FORMA, PUEDEN UTILIZARSE EN TERAPIAS DE VARIAS PATOLOGIAS DEL SISTEMA NERVIOSO, TAMBIEN SE PRESENTAN COMPOSICIONES FARMACEUTICAS Y UTILIDADES TERAPEUTICAS DE LOS DERIVADOS DILISOGANGLIOSIDOS.
ES90402139T 1989-07-27 1990-07-25 Analogos de gangliosidos semisinteticos. Expired - Lifetime ES2106025T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8948246A IT1232175B (it) 1989-07-27 1989-07-27 Analoghi semisintetici di gangliosidi

Publications (1)

Publication Number Publication Date
ES2106025T3 true ES2106025T3 (es) 1997-11-01

Family

ID=11265466

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90402139T Expired - Lifetime ES2106025T3 (es) 1989-07-27 1990-07-25 Analogos de gangliosidos semisinteticos.

Country Status (16)

Country Link
US (1) US5484775A (es)
EP (1) EP0410881B1 (es)
JP (1) JPH0358995A (es)
KR (1) KR910002887A (es)
AT (1) ATE158297T1 (es)
AU (1) AU5982990A (es)
CA (1) CA2022138A1 (es)
DE (1) DE69031448T2 (es)
ES (1) ES2106025T3 (es)
FI (1) FI903753A0 (es)
HU (1) HU210923B (es)
IL (1) IL95169A0 (es)
IT (1) IT1232175B (es)
NO (1) NO903333L (es)
NZ (1) NZ234649A (es)
PL (1) PL165209B1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1232176B (it) * 1989-07-27 1992-01-25 Fidia Farmaceutici Derivati di-lisogangliosidi
IT1239060B (it) * 1990-05-04 1993-09-20 Fidia Spa Processo per la modulazione selettiva dell'espressione e della funzione di un determinante sulla superficie cellulare attraverso appropriati agenti chimici
IT1253832B (it) * 1991-08-01 1995-08-29 Fidia Spa Derivati di gangliosidi
DE4204907A1 (de) * 1992-02-14 1993-08-19 Reutter Werner Neuartige glykokonjugate mit n-substituierten neuraminsaeuren als mittel zur stimulierung des immunsystems
EP1435972B1 (en) 2001-08-29 2016-03-09 Seneb Biosciences Inc. Novel synthetic ganglioside derivatives and compositions thereof
EP1603932B1 (en) 2003-03-06 2012-10-03 Seneb Biosciences Inc. Methods and compositions for the enzymatic synthesis of gangliosides
US20120035120A1 (en) * 2009-03-25 2012-02-09 Seneb Biosciences, Inc. Glycolipids as treatment for disease
PE20181031A1 (es) 2015-10-09 2018-06-27 Tensar Corp Llc Geomalla hecha a partir de un polimero estratificado coextruido

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4716223A (en) * 1981-08-04 1987-12-29 Fidia, S.P.A. Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions
US4593091A (en) * 1981-08-04 1986-06-03 Fidia, S.P.A. Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions
US4476119A (en) * 1981-08-04 1984-10-09 Fidia S.P.A. Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions
IT1199116B (it) * 1984-07-03 1988-12-30 Fidia Farmaceutici Derivati di gangliosidi
JPH06795B2 (ja) * 1985-04-02 1994-01-05 理化学研究所 アシアロガングリオシド関連化合物の製造方法
ES2065343T3 (es) * 1987-06-26 1995-02-16 Solco Basel Ag Nuevos preparados farmaceuticos asi como nuevos compuestos de lactosilo y su preparacion.
IT1212041B (it) * 1987-11-02 1989-11-08 Fidia Farmaceutici Gangliosidi esteri interni come agenti terapeutici capaci di eliminare il dolore nelle neuropatie periferiche
CA1339488C (en) * 1988-02-12 1997-10-07 Taeko Dohi De-n-acetyl-syalic acid and their applications as modifiers of cell physiology
IT1235161B (it) * 1988-12-02 1992-06-22 Fidia Farmaceutici Derivati di lisogangliosidi
IT1253832B (it) * 1991-08-01 1995-08-29 Fidia Spa Derivati di gangliosidi

Also Published As

Publication number Publication date
HU210923B (en) 1995-09-28
JPH0358995A (ja) 1991-03-14
EP0410881A3 (en) 1993-01-20
NO903333L (no) 1991-01-28
EP0410881A2 (en) 1991-01-30
PL286249A1 (en) 1991-08-26
NZ234649A (en) 1992-01-29
HU904640D0 (en) 1991-01-28
IL95169A0 (en) 1991-06-10
DE69031448D1 (de) 1997-10-23
ATE158297T1 (de) 1997-10-15
EP0410881B1 (en) 1997-09-17
DE69031448T2 (de) 1998-02-26
FI903753A0 (fi) 1990-07-27
KR910002887A (ko) 1991-02-26
IT1232175B (it) 1992-01-25
IT8948246A0 (it) 1989-07-27
HUT54173A (en) 1991-01-28
PL165209B1 (pl) 1994-11-30
US5484775A (en) 1996-01-16
AU5982990A (en) 1991-01-31
CA2022138A1 (en) 1991-01-28
NO903333D0 (no) 1990-07-26

Similar Documents

Publication Publication Date Title
EA200100298A1 (ru) ФАРМАЦЕВТИЧЕСКИЕ ПРЕПАРАТЫ С РЕГУЛИРУЕМЫМ ВЫСВОБОЖДЕНИЕМ, СОДЕРЖАЩИЕ ИНГИБИТОР cGMP-ФОСФОДИЭСТЕРАЗЫ-5
ITRM920155A0 (it) Composizione farmaceutica contenente 3-2 (dimetilammino) etil-n-metil-1h-indol-5-metansolfonammide, e relativo procedimento di preparazione e trattamento con essa di mammiferi.
DE3687224D1 (de) Hemmung vom 5-lipoxygenase-weg.
ES2095432T3 (es) Derivados de 2,4-tiazolidin-diona, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
IT8322832A0 (it) Dispositivo per la somministrazione controllata di farmaci.
BR9713404A (pt) ésteres de n-(aril/heteroarilacetil) aminoácidos, composições farmacêuticas compreendendo os mesmos, e métodos para a inibição da liberação de peptìdeo beta-amilóide e/ou de sua sìntese por uso de tais compostos.
IL101358A0 (en) Crystalline tiagabine hydrochloride monohydrate,its preparation and pharmaceutical compositions containing it
FR2711140B1 (fr) 1-Naphtylpyrazole-3-carboxamides substitués actifs sur la neurotensine, leur préparation, les compositions pharmaceutiques en contenant.
ES2106025T3 (es) Analogos de gangliosidos semisinteticos.
ES2129392T3 (es) Derivados de di-lisogangliosidos.
MX9203361A (es) Composiciones farmaceuticas que contienen cloruro de galio.
NO923266D0 (no) Heksahydrobenzo(f)quinolinoner
HUP0004362A2 (hu) Karbamazepint vagy származékait tartalmazó parenterális készítmények
IT8821570A0 (it) Impiego di derivati adenosinici per la preparazione di composizioni farmaceutiche aventi attivita' immunostimolante.
IT8722647A0 (it) Composizione farmaceutica per somministrazione nasale.
IT8720034A0 (it) Composizioni farmaceutiche per il trattamento di sindromi psico-organiche cerebrali.
ITRM910191A1 (it) Composizione farmaceutica liquida per somministrazione endonasale.
IT8709337A0 (it) Sistema di funzionamento elettrico per accessori elettrici di tavoli, mensole o piani di appoggio.
IT8820070A0 (it) 2_0_acetil_1,3_bis_difosfato_di_l_carnitina e di esteri della l_carnitina, procedimento per lasua preparazione e formulazioni farmaceutiche che lo contengono.
ES1014509Y (es) Dispositivo para la administracion de farmacos por via uretral.
IT8720708A0 (it) Sistema terapeutico per la cessione controllata di farmaci.
ITMI913461A1 (it) Composizioni terapeutiche adatte per la somministrazione rettale contenenti come principio attivo uno o piu' tioesteri del glutatione
MX9203260A (es) Derivados anillados del acido tetrahidropiridinacetico y composiciones farmaceuticas que los contienen.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 410881

Country of ref document: ES