ES2105596T3 - Procedimiento para la preparacion de un acido oxazolidina-1,3-carboxilico-5. - Google Patents

Procedimiento para la preparacion de un acido oxazolidina-1,3-carboxilico-5.

Info

Publication number
ES2105596T3
ES2105596T3 ES94900207T ES94900207T ES2105596T3 ES 2105596 T3 ES2105596 T3 ES 2105596T3 ES 94900207 T ES94900207 T ES 94900207T ES 94900207 T ES94900207 T ES 94900207T ES 2105596 T3 ES2105596 T3 ES 2105596T3
Authority
ES
Spain
Prior art keywords
radical
pct
date
preparation
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94900207T
Other languages
English (en)
Inventor
Jean-Noel Denis
Andrew Greene
Alice Kanazawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Application granted granted Critical
Publication of ES2105596T3 publication Critical patent/ES2105596T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCESO DE PREPARACION DE UN ACIDO OXAZOLIDINA-1,3 CARBOXILICO-5 DE FORMULA GENERAL (I) A PARTIR DE FORMULA GENERAL (II). EN LAS FORMULAS GENERALES (I) Y (II): AR REPRESENTA UN RADICAL ARILO, R1 REPRESENTA UN RADICAL BENZOILO O UN RADICAL R2-O-CO- EN EL QUE R2 REPRESENTA UN RADICAL ALCOILO, ALCENILO, ALCINILO, CICLOALCOILO, CICLOALCENILO, BICICLOALCOILO, FENILO O HETEROCICLILO, PH REPRESENTA UN RADIAL FENILO EVENTUALMENTE SUSTITUIDO, X REPRESENTA EL RESTO DE UNA BASE ORGANICA OPTICAMENTE ACTIVA O UN RADICAL ALCOXI EVENTUALMENTE SUSTITUIDO POR UN RADICAL FENILO. LOS ACIDOS DE FORMULA GENERAL (I) SON PARTICULARMENTE UTILES PARA PREPARAR EL TAXOL, EL TAXOTERO O SUS ANALOGOS QUE PRESENTAN PROPIEDADES ANTITUMORALES Y ANTILEUCEMICOS NOTABLES.
ES94900207T 1992-11-20 1993-11-18 Procedimiento para la preparacion de un acido oxazolidina-1,3-carboxilico-5. Expired - Lifetime ES2105596T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9213939A FR2698361B1 (fr) 1992-11-20 1992-11-20 Procédé de préparation d'un acide oxazolidine-1,3 carboxylique-5.

Publications (1)

Publication Number Publication Date
ES2105596T3 true ES2105596T3 (es) 1997-10-16

Family

ID=9435720

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94900207T Expired - Lifetime ES2105596T3 (es) 1992-11-20 1993-11-18 Procedimiento para la preparacion de un acido oxazolidina-1,3-carboxilico-5.

Country Status (25)

Country Link
US (1) US5811550A (es)
EP (1) EP0669915B1 (es)
JP (1) JP3648554B2 (es)
KR (1) KR100330317B1 (es)
AT (1) ATE154600T1 (es)
AU (1) AU679195B2 (es)
CA (1) CA2149637C (es)
CZ (1) CZ283525B6 (es)
DE (1) DE69311736T2 (es)
DK (1) DK0669915T3 (es)
ES (1) ES2105596T3 (es)
FI (1) FI119289B (es)
FR (2) FR2698361B1 (es)
GR (1) GR3023803T3 (es)
HU (1) HU221164B1 (es)
MX (1) MX9306923A (es)
NO (1) NO304786B1 (es)
NZ (1) NZ257875A (es)
OA (1) OA10155A (es)
PL (1) PL176659B1 (es)
RU (1) RU2114834C1 (es)
SK (2) SK280964B6 (es)
TW (1) TW305839B (es)
WO (1) WO1994012482A1 (es)
ZA (1) ZA938588B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2706457B1 (fr) * 1993-06-16 1995-07-28 Rhone Poulenc Rorer Sa Procédé de préparation d'un acide oxazolidinecarboxylique utile pour préparer des taxoïdes thérapeutiquement actifs.
WO2002066448A1 (en) * 2001-02-20 2002-08-29 Dabur India Limited Method of preparation of paclitaxel (taxol) using 3-(alk-2-ynyloxy) carbonyl-5-oxazolidine carboxylic acid
FR2986526A1 (fr) 2012-02-03 2013-08-09 Sanofi Sa Procede de preparation de derives du taxol et certains composes intermediaires

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4162251A (en) * 1976-04-05 1979-07-24 Sankyo Company Limited Process for the preparation of β-lactam compounds
USRE34277E (en) * 1988-04-06 1993-06-08 Centre National De La Recherche Scientifique Process for preparing taxol
MX9102128A (es) * 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
FR2696458B1 (fr) * 1992-10-05 1994-11-10 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.
FR2696464B1 (fr) * 1992-10-05 1994-11-10 Rhone Poulenc Rorer Sa Nouveau procédé d'estérification de la baccatine III et de la désacétyl-10 baccatine III.
FR2696459B1 (fr) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.
FR2696460B1 (fr) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.
US5521310A (en) * 1992-10-07 1996-05-28 Derivados Del Etilo, S.A. Process to obtain benzoxazines to be used for the synthesis of ofloxazine, levofloxazine and derivatives
DE4239445C2 (de) * 1992-11-24 1995-12-14 Hagen Kinsel Vorrichtung zum Beladen von mit Revolvertrommeln ausgerüsteten Waffen
FR2698871B1 (fr) * 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR2702212B1 (fr) * 1993-03-02 1995-04-07 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US5502192A (en) * 1994-08-08 1996-03-26 Ciba-Geigy Corporation Process for the preparation of quinacridones from dihydroquinacridones in an aqueous medium

Also Published As

Publication number Publication date
NO951840D0 (no) 1995-05-10
US5811550A (en) 1998-09-22
SK66295A3 (en) 1995-10-11
TW305839B (es) 1997-05-21
DE69311736T2 (de) 1997-11-13
CZ131095A3 (en) 1995-10-18
JP3648554B2 (ja) 2005-05-18
ATE154600T1 (de) 1997-07-15
PL309567A1 (en) 1995-10-30
HUT73439A (en) 1996-07-29
DK0669915T3 (da) 1997-08-18
JPH08503485A (ja) 1996-04-16
AU679195B2 (en) 1997-06-26
EP0669915A1 (fr) 1995-09-06
SK280965B6 (sk) 2000-10-09
CA2149637A1 (fr) 1994-06-09
FR2698361A1 (fr) 1994-05-27
NO304786B1 (no) 1999-02-15
NZ257875A (en) 1998-03-25
RU2114834C1 (ru) 1998-07-10
FI952462A (fi) 1995-05-19
CZ283525B6 (cs) 1998-04-15
RU95113420A (ru) 1997-02-10
KR100330317B1 (ko) 2002-09-27
NO951840L (no) 1995-05-10
CA2149637C (fr) 2006-08-29
FI119289B (fi) 2008-09-30
GR3023803T3 (en) 1997-09-30
EP0669915B1 (fr) 1997-06-18
PL176659B1 (pl) 1999-07-30
MX9306923A (es) 1994-06-30
SK280964B6 (sk) 2000-10-09
FR2698361B1 (fr) 1995-01-13
FR2698360B1 (fr) 1994-12-30
DE69311736D1 (de) 1997-07-24
HU221164B1 (en) 2002-08-28
FI952462A0 (fi) 1995-05-19
FR2698360A1 (fr) 1994-05-27
OA10155A (fr) 1996-12-18
HU9501474D0 (en) 1995-07-28
WO1994012482A1 (fr) 1994-06-09
KR950704276A (ko) 1995-11-17
AU5468894A (en) 1994-06-22
ZA938588B (en) 1995-01-18

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