ES2101644A1 - New compound derived from chromene - Google Patents

New compound derived from chromene

Info

Publication number
ES2101644A1
ES2101644A1 ES09500163A ES9500163A ES2101644A1 ES 2101644 A1 ES2101644 A1 ES 2101644A1 ES 09500163 A ES09500163 A ES 09500163A ES 9500163 A ES9500163 A ES 9500163A ES 2101644 A1 ES2101644 A1 ES 2101644A1
Authority
ES
Spain
Prior art keywords
chromene
new compound
compound derived
schizophrenia
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09500163A
Other languages
Spanish (es)
Other versions
ES2101644B1 (en
Inventor
Ambros Rafael Foguet
Gener Jordi Bolos
Munoz Aurelio Sacristan
Hernandez Jose A Ortiz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferrer Internacional SA
Original Assignee
Ferrer Internacional SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Internacional SA filed Critical Ferrer Internacional SA
Priority to IL11276495A priority Critical patent/IL112764A0/en
Priority to AU20720/95A priority patent/AU683549B2/en
Priority to NZ282810A priority patent/NZ282810A/en
Priority to PT95913143T priority patent/PT699197E/en
Priority to KR1019950705162A priority patent/KR0182088B1/en
Priority to DK95913143T priority patent/DK0699197T3/en
Priority to US08/532,791 priority patent/US5643927A/en
Priority to EP95913143A priority patent/EP0699197B1/en
Priority to DE69517371T priority patent/DE69517371T2/en
Priority to CA002163251A priority patent/CA2163251A1/en
Priority to AT95913143T priority patent/ATE193705T1/en
Priority to JP52437695A priority patent/JP3170287B2/en
Priority to PCT/EP1995/001008 priority patent/WO1995025733A1/en
Priority to PH50033A priority patent/PH31442A/en
Priority to FI955386A priority patent/FI955386A0/en
Priority to NO954633A priority patent/NO308001B1/en
Publication of ES2101644A1 publication Critical patent/ES2101644A1/en
Application granted granted Critical
Publication of ES2101644B1 publication Critical patent/ES2101644B1/en
Priority to GR20000401911T priority patent/GR3034226T3/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

New compound derived from chromene Comprises the new compound derived from chromene of formula I: < IMAGE > and its pharmaceutically acceptable addition salts. These compounds are of potential use in treating psychosis and schizophrenia.
ES09500163A 1994-03-18 1995-01-30 NEW CHROME-DERIVED COMPOUND Expired - Lifetime ES2101644B1 (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
IL11276495A IL112764A0 (en) 1994-03-18 1995-02-23 New chromene derivatives
PCT/EP1995/001008 WO1995025733A1 (en) 1994-03-18 1995-03-17 4-p-fluorobenzoyl-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis and schizophrenia
PT95913143T PT699197E (en) 1994-03-18 1995-03-17 DERIVATIVES OF 4-P-FLUOROBENZOYL-1-PIPERIDINYL-PROPOXY-CROMEN-4-PREPARATION AND ITS USE IN THE TREATMENT OF PSYCHOSIS AND SCHIZOPHRENIA
KR1019950705162A KR0182088B1 (en) 1994-03-18 1995-03-17 4-p-fluorobenzoyl-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment
DK95913143T DK0699197T3 (en) 1994-03-18 1995-03-17 4-p-Fluorobenzoyl-1-piperidinyl-propoxy-chromene-4-one derivatives, their preparation and their use in the treatment of psy
US08/532,791 US5643927A (en) 1994-03-18 1995-03-17 4-p-fluorobenzoyl-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis and schizophrenia
EP95913143A EP0699197B1 (en) 1994-03-18 1995-03-17 4-p-fluorobenzoyl-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis and schizophrenia
DE69517371T DE69517371T2 (en) 1994-03-18 1995-03-17 4-P-FLUORBENZOYL-1-PIPERIDINYL-PROPOXY-CHROMEN-4-ON DERIVATIVES, THEIR PRODUCTION AND THE USE THEREOF FOR THE TREATMENT OF PSYCHOSES AND SCHIZOPHRENIA
AU20720/95A AU683549B2 (en) 1994-03-18 1995-03-17 4-P-fluorobenzoyl-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of Psychosis and Schizophrenia
AT95913143T ATE193705T1 (en) 1994-03-18 1995-03-17 4-P-FLUORBENZOYL-1-PIPERIDINYL-PROPOXY-CHROME-ON DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR THE TREATMENT OF PSYCHOSIS AND SCHIZOPHRENIA
JP52437695A JP3170287B2 (en) 1994-03-18 1995-03-17 4-p-Fluorobenzoyl-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis and schizophrenia
NZ282810A NZ282810A (en) 1994-03-18 1995-03-17 7-(4-(4-fluorobenzoyl)-piperidin-1-ylpropyloxy)- chromen-4-one derivatives; pharmaceutical compositions
CA002163251A CA2163251A1 (en) 1994-03-18 1995-03-17 4-p-fluorobenzoyl-1-piperidinyl-propoxy-chromen-4-one derivatives
PH50033A PH31442A (en) 1994-03-18 1995-03-27 New chromene derivative compounds.
FI955386A FI955386A0 (en) 1994-03-18 1995-11-08 4-p-Fluorobenzoyl-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and use in the treatment of psychosis and schizophrenia
NO954633A NO308001B1 (en) 1994-03-18 1995-11-16 New chromium compounds, their use for the preparation of a preparation and pharmaceutical composition containing chromium compounds
GR20000401911T GR3034226T3 (en) 1994-03-18 2000-08-17 4-p-fluorobenzoyl-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis and schizophrenia

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09400581A ES2101620B1 (en) 1994-03-18 1994-03-18 NEW COMPOUND DERIVED FROM CHROMENE.

Publications (2)

Publication Number Publication Date
ES2101644A1 true ES2101644A1 (en) 1997-07-01
ES2101644B1 ES2101644B1 (en) 1998-04-01

Family

ID=8285614

Family Applications (3)

Application Number Title Priority Date Filing Date
ES09400581A Expired - Lifetime ES2101620B1 (en) 1994-03-18 1994-03-18 NEW COMPOUND DERIVED FROM CHROMENE.
ES09401437A Expired - Lifetime ES2101635B1 (en) 1994-03-18 1994-07-01 NEW CHROME-DERIVED COMPOUND
ES09500163A Expired - Lifetime ES2101644B1 (en) 1994-03-18 1995-01-30 NEW CHROME-DERIVED COMPOUND

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES09400581A Expired - Lifetime ES2101620B1 (en) 1994-03-18 1994-03-18 NEW COMPOUND DERIVED FROM CHROMENE.
ES09401437A Expired - Lifetime ES2101635B1 (en) 1994-03-18 1994-07-01 NEW CHROME-DERIVED COMPOUND

Country Status (3)

Country Link
KR (1) KR0182088B1 (en)
ES (3) ES2101620B1 (en)
ZA (1) ZA951962B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2154176A1 (en) * 1998-09-21 2001-03-16 Ferrer Int 3-(hydroxymethyl)chromen-4-ones and process for their preparation

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4428955A (en) * 1981-05-02 1984-01-31 Boehringer Mannheim Gmbh Benzopyran compounds, pharmaceutical compositions containing them and methods of use
EP0190015A1 (en) * 1985-01-30 1986-08-06 Warner-Lambert Company Novel 4H-1-benzopyran-4-ones and their sulphur containing analogs
US4950674A (en) * 1985-12-20 1990-08-21 A. H. Robins Company, Incorporated Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment
WO1991018597A1 (en) * 1990-06-04 1991-12-12 Erickson Ronald H Sigma binding site agents
EP0558245A1 (en) * 1992-02-25 1993-09-01 RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY Heterobicyclic compounds as antagogists of alpha-1 adrenergic and SHT1A receptors

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4428955A (en) * 1981-05-02 1984-01-31 Boehringer Mannheim Gmbh Benzopyran compounds, pharmaceutical compositions containing them and methods of use
EP0190015A1 (en) * 1985-01-30 1986-08-06 Warner-Lambert Company Novel 4H-1-benzopyran-4-ones and their sulphur containing analogs
US4950674A (en) * 1985-12-20 1990-08-21 A. H. Robins Company, Incorporated Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment
WO1991018597A1 (en) * 1990-06-04 1991-12-12 Erickson Ronald H Sigma binding site agents
EP0558245A1 (en) * 1992-02-25 1993-09-01 RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY Heterobicyclic compounds as antagogists of alpha-1 adrenergic and SHT1A receptors

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ERICKSON H. et al.: "(Aminoalkoxy)chromones. Selective alfa receptor ligands". J. Med. Chem. Vol. 35, 1992, pßginas 1526-1535 * Tabla I * *
JAEN, J.C. et al.: "Dopamine autoreceptor agonist as potential antipsychotics. 2 (Aminoalkoxy)-4H-1-benzopyran-4-ones. J. Med. Chem. Vol. 34, 1991, pßginas 248-256 * Tabla I * *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2154176A1 (en) * 1998-09-21 2001-03-16 Ferrer Int 3-(hydroxymethyl)chromen-4-ones and process for their preparation

Also Published As

Publication number Publication date
KR0182088B1 (en) 1999-05-01
ES2101620B1 (en) 1998-04-01
ES2101620A1 (en) 1997-07-01
ES2101635B1 (en) 1998-04-01
KR960702457A (en) 1996-04-27
ES2101644B1 (en) 1998-04-01
ZA951962B (en) 1996-03-12
ES2101635A1 (en) 1997-07-01

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