ES2101300T3 - Polimero que contiene polietilenglicol o polipropilenglicol. - Google Patents

Polimero que contiene polietilenglicol o polipropilenglicol.

Info

Publication number
ES2101300T3
ES2101300T3 ES93903869T ES93903869T ES2101300T3 ES 2101300 T3 ES2101300 T3 ES 2101300T3 ES 93903869 T ES93903869 T ES 93903869T ES 93903869 T ES93903869 T ES 93903869T ES 2101300 T3 ES2101300 T3 ES 2101300T3
Authority
ES
Spain
Prior art keywords
glycol
polymer
peptides
proteins
propylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93903869T
Other languages
English (en)
Inventor
Morten Peter Meldal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Carlsberg AS
Original Assignee
Carlsberg AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlsberg AS filed Critical Carlsberg AS
Application granted granted Critical
Publication of ES2101300T3 publication Critical patent/ES2101300T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/06Polymers provided for in subclass C08G
    • C08F290/062Polyethers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Polyethers (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

UN GLICOL DE POLIETILENO O POLIPROPLENO DEGRADADO, CONTENIENDO POLIMERO, EL CUAL TIENE UNA ESTRUCTURA ESPACIAL UNICA Y PUEDE DESIGNARSE ESPECIALMENTE PARA APLICACION COMO UNA RESINA CROMATOGRAFICA, O COMO UN SOPORTE SOLIDO PARA LA SINTESIS DE PEPTIDOS, OLIGONUCLETOIDOS U OLIGOSACARIDOS, O COMO UN SUSTRATO PARA LA INMOVILIZACION DE PROTEINAS. EL POLIMERO SE FORMA MEDIANTE COPOLIMERIZACION RADICAL DE GLICOL DE POLIETILENO DERIVADO O GLICOL DE POLIPROPILENO BIS-TERMINAL, SUSTITUIDO CON UNA MITAD SELECCIONADA DEL GRUPO FORMADO POR ACRILOALQUILO, ACRILOARILO, ACRILAMIDOALQUILO Y ACRILAMIDOARILO, CON AMIDA ACRILICA, NITRILO O ESTER. CUANDO SE VA A USAR COMO UN SOPORTE SOLIDO O SUSTRATO DE INMOVILIZACION, EL POLIMERO INCORPORARA UN SEPARADOR, COMPRENDIENDO GRUPOS FUNCIONALES PARA LA UNION DE PEPTIDOS, PROTEINAS, NUCLEOTIDOS O SACARIDOS TALES COMO LOS SELECCIONADOS DEL GRUPO FORMADO POR AMINO, ALQUILAMINO, HIDROXI, CARBOXIL, MERCAPTO, SULFENO, SULFINO, SULFO Y DERIVADOS DE LOS MISMOS.
ES93903869T 1992-02-13 1993-02-12 Polimero que contiene polietilenglicol o polipropilenglicol. Expired - Lifetime ES2101300T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83527792A 1992-02-13 1992-02-13

Publications (1)

Publication Number Publication Date
ES2101300T3 true ES2101300T3 (es) 1997-07-01

Family

ID=25269099

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93903869T Expired - Lifetime ES2101300T3 (es) 1992-02-13 1993-02-12 Polimero que contiene polietilenglicol o polipropilenglicol.

Country Status (11)

Country Link
US (1) US5352756A (es)
EP (1) EP0625996B1 (es)
JP (1) JPH07503744A (es)
AT (1) ATE152143T1 (es)
AU (1) AU660534B2 (es)
BR (1) BR9305894A (es)
CA (1) CA2129442C (es)
DE (1) DE69310148T2 (es)
DK (1) DK0625996T3 (es)
ES (1) ES2101300T3 (es)
WO (1) WO1993016118A1 (es)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5766897A (en) * 1990-06-21 1998-06-16 Incyte Pharmaceuticals, Inc. Cysteine-pegylated proteins
US5656707A (en) * 1995-06-16 1997-08-12 Regents Of The University Of Minnesota Highly cross-linked polymeric supports
DE19625397A1 (de) * 1996-06-25 1998-01-08 Deutsches Krebsforsch Verfahren zur Kombination von paralleler Oligonukleotidsynthese und Darstellung von Oligomer-Chips
DE19741356C2 (de) * 1997-09-19 2001-02-15 Cognis Deutschland Gmbh Verwendung von Glucoprotaminen
ES2232176T5 (es) 1998-09-28 2007-09-16 Novo Nordisk A/S Macromonomeros basados en peg, polimeros quimicamente inertes preparados a partir de los mismos y el uso de estos polimeros para sintesis organica y reacciones enzimaticas.
US6907679B2 (en) * 1998-11-12 2005-06-21 Qlt Usa, Inc. Method for lyophilizing an active agent
US6722054B2 (en) 1998-11-12 2004-04-20 Atrix Laboratories, Inc. Process and delivery container for lyophilizing active agent
GB9926435D0 (en) * 1999-11-08 2000-01-12 Polymer Lab Ltd Method
US6566144B1 (en) * 2000-03-27 2003-05-20 Atrix Laboratories Cover plate for use in lyophilization
MXPA03000310A (es) * 2000-07-12 2004-12-13 Gryphon Therapeutics Inc Quimiocinas sinteticas bioactivas, modificadas con polimeros y metodos para su elaboracion y uso.
AU2001278905B2 (en) * 2000-09-08 2004-12-16 Gryphon Therapeutics, Inc. Synthetic erythropoiesis stimulating proteins
US7118737B2 (en) * 2000-09-08 2006-10-10 Amylin Pharmaceuticals, Inc. Polymer-modified synthetic proteins
EP1352003B1 (en) * 2000-11-20 2006-01-18 Matrix Innovation Inc. Method for the preparation of amphiphile solid support for peptide synthesis, bioorganic and organic chemistry
US6979530B2 (en) * 2001-05-21 2005-12-27 Applera Corporation Peptide conjugates and fluorescence detection methods for intracellular caspase assay
US20040077835A1 (en) * 2001-07-12 2004-04-22 Robin Offord Chemokine receptor modulators, production and use
AU2002326103A1 (en) * 2001-08-24 2003-03-10 University Of British Columbia Solid-phase synthesis of oligosaccharides and glycopeptides using glycosynthases
EP1448644A2 (en) * 2001-10-12 2004-08-25 Carlsberg A/S Matrix for solid-phase organic synthesis
WO2004061094A1 (en) 2002-12-30 2004-07-22 Gryphon Therapeutics, Inc. Water-soluble thioester and selenoester compounds and methods for making and using the same
US7842767B2 (en) 2003-08-04 2010-11-30 Matrix Innovation Inc. Polyether based monomers and highly cross-linked amphiphile resins
CA2602654A1 (en) 2005-04-05 2006-10-12 Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa Method for shielding functional sites or epitopes on proteins
US7985783B2 (en) 2006-09-21 2011-07-26 The Regents Of The University Of California Aldehyde tags, uses thereof in site-specific protein modification
US9150846B2 (en) 2011-07-05 2015-10-06 Bioasis Technologies, Inc. P97-antibody conjugates and methods of use
WO2014022515A1 (en) 2012-07-31 2014-02-06 Bioasis Technologies, Inc. Dephosphorylated lysosomal storage disease proteins and methods of use thereof
WO2014074218A1 (en) 2012-11-12 2014-05-15 Redwood Bioscience, Inc. Compounds and methods for producing a conjugate
US9605078B2 (en) 2012-11-16 2017-03-28 The Regents Of The University Of California Pictet-Spengler ligation for protein chemical modification
US9310374B2 (en) 2012-11-16 2016-04-12 Redwood Bioscience, Inc. Hydrazinyl-indole compounds and methods for producing a conjugate
EP2970433B1 (en) 2013-03-13 2019-09-18 Bioasis Technologies Inc. Fragments of p97 and uses thereof
US20150093399A1 (en) 2013-08-28 2015-04-02 Bioasis Technologies, Inc. Cns-targeted conjugates having modified fc regions and methods of use thereof
CA2927806C (en) 2013-11-27 2023-01-10 Redwood Bioscience, Inc. Hydrazinyl-pyrrolo compounds and methods for producing a conjugate
AR107541A1 (es) 2016-02-05 2018-05-09 Tolmar Therapeutics Inc Placa de recubrimiento ventilada para un conjunto de jeringas
CN111094462A (zh) 2017-12-26 2020-05-01 贝克顿·迪金森公司 深紫外线可激发的水溶剂化聚合物染料
US10844228B2 (en) 2018-03-30 2020-11-24 Becton, Dickinson And Company Water-soluble polymeric dyes having pendant chromophores
USD908916S1 (en) 2018-06-19 2021-01-26 Tolmar Therapeutics, Inc. Syringe restrictor plate
CA3107332A1 (en) 2018-07-22 2020-01-30 Bioasis Technologies Inc. Treatment of lymphatic metastases
US20210355468A1 (en) 2020-05-18 2021-11-18 Bioasis Technologies, Inc. Compositions and methods for treating lewy body dementia
US20210393787A1 (en) 2020-06-17 2021-12-23 Bioasis Technologies, Inc. Compositions and methods for treating frontotemporal dementia
EP4155349A1 (en) 2021-09-24 2023-03-29 Becton, Dickinson and Company Water-soluble yellow green absorbing dyes
WO2024007016A2 (en) 2022-07-01 2024-01-04 Beckman Coulter, Inc. Novel fluorescent dyes and polymers from dihydrophenanthrene derivatives
WO2024044327A1 (en) 2022-08-26 2024-02-29 Beckman Coulter, Inc. Dhnt monomers and polymer dyes with modified photophysical properties

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4644038A (en) * 1985-09-30 1987-02-17 A. E. Staley Manufacturing Company Unsaturated poly (alpha-hydroxy acid) copolymers
JP2541614B2 (ja) * 1988-03-17 1996-10-09 鐘淵化学工業株式会社 硬化性組成物
US5087690A (en) * 1989-01-24 1992-02-11 Monsanto Hybrid amino resin compositions
US5130405A (en) * 1989-07-13 1992-07-14 Akzo N.V. Acid etch resistant coatings

Also Published As

Publication number Publication date
EP0625996A1 (en) 1994-11-30
CA2129442C (en) 2003-05-27
WO1993016118A1 (en) 1993-08-19
CA2129442A1 (en) 1993-08-14
DE69310148D1 (de) 1997-05-28
AU3493493A (en) 1993-09-03
JPH07503744A (ja) 1995-04-20
EP0625996B1 (en) 1997-04-23
US5352756A (en) 1994-10-04
AU660534B2 (en) 1995-06-29
DE69310148T2 (de) 1997-07-31
DK0625996T3 (da) 1997-06-02
BR9305894A (pt) 1997-08-19
ATE152143T1 (de) 1997-05-15

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