ES210045A1 - A procedure for the preparation of testosterone and its esteres (Machine-translation by Google Translate, not legally binding)
- Google Patents
A procedure for the preparation of testosterone and its esteres (Machine-translation by Google Translate, not legally binding)
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Drogas Vacunas y Sueros SA
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Drogas Vacunas y Sueros SA
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Priority to ES210045ApriorityCriticalpatent/ES210045A1/en
Publication of ES210045A1publicationCriticalpatent/ES210045A1/en
Procedure for the preparation of testosterone and its esters from delta-4-androsten-3.17-dione, characterized in that testosterone is obtained by reacting delta-4-androsten-3.17-dione with a hydrocyanic acid donor able to transform it selectively in delta-4-androsten-17-cyan-17-01-3-one; the carbonyl group of this intermediate product is successively protected by transforming it into a group which can not be attacked by the nascent hydrogen in an alkaline medium, and the new compound thus obtained is subjected to the joint action of an aliphatic alcohol and an alkali metal so as to eliminate the cn group in position 17 obtaining in solution a derivative of testosterone in which the carbonyl group is still protected which at last gently hydrolyzed provides testosterone. (Machine-translation by Google Translate, not legally binding)
ES210045A1953-06-271953-06-27A procedure for the preparation of testosterone and its esteres (Machine-translation by Google Translate, not legally binding)
ExpiredES210045A1
(en)
Procedure for the obtaining of a hetitic dieter of a dihydroxycide of pharmaceutical interest. (Machine-translation by Google Translate, not legally binding)