ES2098304T3 - Anticuerpos monoclonales frente a cadenas de hidratos de carbono glucolipidicas. - Google Patents

Anticuerpos monoclonales frente a cadenas de hidratos de carbono glucolipidicas.

Info

Publication number
ES2098304T3
ES2098304T3 ES91120585T ES91120585T ES2098304T3 ES 2098304 T3 ES2098304 T3 ES 2098304T3 ES 91120585 T ES91120585 T ES 91120585T ES 91120585 T ES91120585 T ES 91120585T ES 2098304 T3 ES2098304 T3 ES 2098304T3
Authority
ES
Spain
Prior art keywords
glycolipidic
monoclonal antibodies
antibodies against
carbon hydrate
chains
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91120585T
Other languages
English (en)
Inventor
Nobuo Hanai
So Ohta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Application granted granted Critical
Publication of ES2098304T3 publication Critical patent/ES2098304T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734—Complement-dependent cytotoxicity [CDC]

Abstract

UN ANTICUERPO MONOCLONAL QUE PERTENECE A LA SUBCLASE IGG3, ES REACTIVO CON AL MENOS UN GANGLIOSIDO Y CON 3'', 8''-LD1 Y QUE TIENE ACTIVIDAD CITOLOGICA, QUE ES UTIL PARA EL TRATAMIENTO DE CARCIROMAS NEUROECTODERMALES.
ES91120585T 1990-11-30 1991-11-29 Anticuerpos monoclonales frente a cadenas de hidratos de carbono glucolipidicas. Expired - Lifetime ES2098304T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP33465990 1990-11-30

Publications (1)

Publication Number Publication Date
ES2098304T3 true ES2098304T3 (es) 1997-05-01

Family

ID=18279829

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91120585T Expired - Lifetime ES2098304T3 (es) 1990-11-30 1991-11-29 Anticuerpos monoclonales frente a cadenas de hidratos de carbono glucolipidicas.

Country Status (6)

Country Link
EP (1) EP0493686B1 (es)
AT (1) ATE148922T1 (es)
DE (1) DE69124683T2 (es)
DK (1) DK0493686T3 (es)
ES (1) ES2098304T3 (es)
GR (1) GR3023290T3 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU669124B2 (en) 1991-09-18 1996-05-30 Kyowa Hakko Kirin Co., Ltd. Process for producing humanized chimera antibody
DE4208795A1 (de) * 1992-03-19 1993-09-23 Behringwerke Ag Monoklonaler anti-gangliosid-antikoerper, seine herstellung und verwendung als tumortherapeutikum
AU4801093A (en) * 1992-07-31 1994-03-03 Duke University Monoclonal antibodies specific for 3',6'-isold1 ganglioside
WO2001023432A1 (fr) 1999-09-30 2001-04-05 Kyowa Hakko Kogyo Co., Ltd. Anticorps humain de transplantation d'une region de determination de la complementarite agissant contre le ganglioside gd3, et derives dudit anticorps

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0234122A3 (en) * 1986-02-21 1989-03-22 Oncogen Limited Partnership Tumor therapy with biologically active anti-tumor antibodies
US4849509A (en) * 1987-02-20 1989-07-18 The Wistar Institute Monoclonal antibodies against melanoma-associated antigens and hybrid cell lines producing these antibodies

Also Published As

Publication number Publication date
DK0493686T3 (da) 1997-03-10
EP0493686A1 (en) 1992-07-08
DE69124683T2 (de) 1997-09-11
DE69124683D1 (de) 1997-03-27
JPH05176791A (ja) 1993-07-20
GR3023290T3 (en) 1997-07-30
EP0493686B1 (en) 1997-02-12
ATE148922T1 (de) 1997-02-15

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