ES2097368T3 - Nuevas proteinas inhibidoras de trombina a partir de sanguijuelas terrestres. - Google Patents
Nuevas proteinas inhibidoras de trombina a partir de sanguijuelas terrestres.Info
- Publication number
- ES2097368T3 ES2097368T3 ES92924598T ES92924598T ES2097368T3 ES 2097368 T3 ES2097368 T3 ES 2097368T3 ES 92924598 T ES92924598 T ES 92924598T ES 92924598 T ES92924598 T ES 92924598T ES 2097368 T3 ES2097368 T3 ES 2097368T3
- Authority
- ES
- Spain
- Prior art keywords
- glu
- gly
- cys
- asp
- lys
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
SE DESCRIBEN NUEVAS PROTEINAS INHIBIDORAS DE TROMBINA OBTENIDAS A PARTIR DE SANGUIJUELAS TERRESTRES DE LA ESPECIE HAEMADIPSA Y CON LA SECUENCIA DE AMINOACIDOS ILE VAL PHE ENTO TERMINAL C DE LA SECUENCIA INDICADA POR MEDIO DE 1 HASTA 12 AMINOACIDOS. LAS PROTEINAS SON ADECUADAS PARA SU UTILIZACION CONTRA ENFERMEDADES. SE DESCRIBE TAMBIEN LA CODIFICACION DE ACIDOS NUCLEICOS PARA ESTAS PROTEINAS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4138698 | 1991-11-26 | ||
DE4209110A DE4209110A1 (de) | 1991-11-26 | 1992-03-20 | Neue thrombininhibitorische proteine aus landblutegeln |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2097368T3 true ES2097368T3 (es) | 1997-04-01 |
Family
ID=25909466
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92924598T Expired - Lifetime ES2097368T3 (es) | 1991-11-26 | 1992-11-19 | Nuevas proteinas inhibidoras de trombina a partir de sanguijuelas terrestres. |
Country Status (10)
Country | Link |
---|---|
US (1) | US5455181A (es) |
EP (1) | EP0616642B1 (es) |
JP (1) | JP3290661B2 (es) |
AT (1) | ATE148744T1 (es) |
CA (1) | CA2121601A1 (es) |
DE (2) | DE4209110A1 (es) |
DK (1) | DK0616642T3 (es) |
ES (1) | ES2097368T3 (es) |
MX (1) | MX9206732A (es) |
WO (1) | WO1993011239A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4234921A1 (de) * | 1992-10-16 | 1994-04-21 | Basf Ag | Neues, die Gerinnungszeit des Blutes verlängerndes Protein aus dem Landblutegel Haemadipsa sylestris |
WO2006045503A1 (en) | 2004-10-19 | 2006-05-04 | Lonza Ag | Method for solid phase peptide synthesis |
US20110034396A1 (en) * | 2005-09-28 | 2011-02-10 | Biovascular, Inc. | Methods and compositions for inhibiting cell migration and treatment of inflammatory conditions |
WO2007038749A2 (en) | 2005-09-28 | 2007-04-05 | Biovascular, Inc. | Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation |
US8685462B1 (en) | 2012-09-17 | 2014-04-01 | Biopep Solutions, Inc. | Whole, leech saliva product and applications thereof |
CN105732789A (zh) * | 2016-03-03 | 2016-07-06 | 中国科学院昆明动物研究所 | 森林山蛭镇痛肽mh2620及其基因和应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3342139A1 (de) * | 1983-11-22 | 1985-05-30 | Ciba-Geigy Ag, Basel | Desulfatohirudine, verfahren zu ihrer herstellung und pharmazeutische mittel |
DE3583361D1 (de) * | 1984-06-14 | 1991-08-08 | Ucp Gen Pharma Ag | Verfahren zur herstellung von thrombin-inhibitoren. |
-
1992
- 1992-03-20 DE DE4209110A patent/DE4209110A1/de not_active Withdrawn
- 1992-11-19 DK DK92924598.3T patent/DK0616642T3/da active
- 1992-11-19 DE DE59208025T patent/DE59208025D1/de not_active Expired - Fee Related
- 1992-11-19 WO PCT/EP1992/002661 patent/WO1993011239A1/de active IP Right Grant
- 1992-11-19 JP JP50976693A patent/JP3290661B2/ja not_active Expired - Fee Related
- 1992-11-19 AT AT92924598T patent/ATE148744T1/de not_active IP Right Cessation
- 1992-11-19 EP EP92924598A patent/EP0616642B1/de not_active Expired - Lifetime
- 1992-11-19 CA CA002121601A patent/CA2121601A1/en not_active Abandoned
- 1992-11-19 ES ES92924598T patent/ES2097368T3/es not_active Expired - Lifetime
- 1992-11-19 US US08/244,113 patent/US5455181A/en not_active Expired - Fee Related
- 1992-11-23 MX MX9206732A patent/MX9206732A/es unknown
Also Published As
Publication number | Publication date |
---|---|
ATE148744T1 (de) | 1997-02-15 |
DK0616642T3 (da) | 1997-07-07 |
EP0616642A1 (de) | 1994-09-28 |
EP0616642B1 (de) | 1997-02-05 |
CA2121601A1 (en) | 1993-06-10 |
JP3290661B2 (ja) | 2002-06-10 |
WO1993011239A1 (de) | 1993-06-10 |
MX9206732A (es) | 1993-05-01 |
JPH07501529A (ja) | 1995-02-16 |
DE59208025D1 (de) | 1997-03-20 |
DE4209110A1 (de) | 1993-05-27 |
US5455181A (en) | 1995-10-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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