ES2096724T3 - Resolucion optica de acido (+/-)-2-(4-isobutilfenil)propionico. - Google Patents
Resolucion optica de acido (+/-)-2-(4-isobutilfenil)propionico.Info
- Publication number
- ES2096724T3 ES2096724T3 ES92307140T ES92307140T ES2096724T3 ES 2096724 T3 ES2096724 T3 ES 2096724T3 ES 92307140 T ES92307140 T ES 92307140T ES 92307140 T ES92307140 T ES 92307140T ES 2096724 T3 ES2096724 T3 ES 2096724T3
- Authority
- ES
- Spain
- Prior art keywords
- propionico
- isobutilfenil
- acid
- optical resolution
- optically active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002253 acid Substances 0.000 title 1
- 230000003287 optical effect Effects 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
UN ACIDO ( (MAS MENOS) )-2-(4-ISOBUTILFENILO)-PROPIONICO PUEDE SER RESUELTO EN ISOMEROS OPTICAMENTE ACTIVOS FACILMENTE Y CON ALTOS RENDIMIENTOS. EL METODO SE CARACTERIZA PRO EL USO DE LA AMINA OPTICAMENTE ACTIVA DE LA SIGUIENTE FORMULA GENERAL (I) O (II) COMO UN AGENTE DE RESOLUCION.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP23721091 | 1991-08-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2096724T3 true ES2096724T3 (es) | 1997-03-16 |
Family
ID=17012017
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92307140T Expired - Lifetime ES2096724T3 (es) | 1991-08-23 | 1992-08-05 | Resolucion optica de acido (+/-)-2-(4-isobutilfenil)propionico. |
Country Status (8)
Country | Link |
---|---|
US (1) | US5321154A (es) |
EP (1) | EP0529835B1 (es) |
JP (1) | JP3135696B2 (es) |
AT (1) | ATE148089T1 (es) |
CA (1) | CA2074932A1 (es) |
DE (1) | DE69216952T2 (es) |
DK (1) | DK0529835T3 (es) |
ES (1) | ES2096724T3 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5602272A (en) * | 1994-06-21 | 1997-02-11 | Bristol-Myers Squibb Company | Reduction and resolution methods for the preparation of compounds useful as intemediates for preparing taxanes |
JPH08151344A (ja) * | 1994-09-26 | 1996-06-11 | Nagase & Co Ltd | 2−(3−ベンゾイルフェニル)プロピオン酸の光学分割方法 |
US5621140A (en) * | 1994-12-22 | 1997-04-15 | Syntex (U.S.A.) Inc. | Resolution of ibuprofen |
DE19624604A1 (de) * | 1996-06-20 | 1998-01-02 | Hoechst Ag | Verfahren zur Herstellung chiraler, nicht racemischer (4-Aryl-2,5-dioxoimidazolidin-1-yl)essigsäuren |
IN183408B (es) * | 1996-11-20 | 1999-12-25 | Kuraray Co | |
JP2000080062A (ja) * | 1998-07-09 | 2000-03-21 | Sumitomo Chem Co Ltd | 光学活性1―アリ―ルアルキルアミン類の製造方法およびその中間体 |
BRPI0914068A2 (pt) * | 2008-11-14 | 2015-10-13 | Watson Pharma Private Ltd | processo de resolução de n-[2-(1,6,7,8-tetra-hidro-2h-indeno[5, 4- b]furano-8-il)]etilamina e ramelteon |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4209638A (en) * | 1977-03-08 | 1980-06-24 | The Boots Company Limited | Preparation of therapeutic agents |
GB1596033A (en) * | 1978-04-25 | 1981-08-19 | Boots Co Ltd | (-)-(2-methoxyphenyl) ethylamine |
US4723033A (en) * | 1982-11-24 | 1988-02-02 | Syntex Pharmaceuticals International Ltd. | Manufacture of optically active α-arylalkanoic acids and precursors thereof |
JPS59152346A (ja) * | 1983-02-18 | 1984-08-31 | Hiroyuki Nohira | 光学活性2−(6−メトキシ−2−ナフチル)プロピオン酸の製造法 |
JPS60228442A (ja) * | 1984-04-27 | 1985-11-13 | Nissan Chem Ind Ltd | 光学活性2−(6−メトキシ−2−ナフチル)プロピオン酸の製造法 |
JPS61172853A (ja) * | 1985-01-29 | 1986-08-04 | Hiroyuki Nohira | (±)−トランス−菊カルボン酸の光学分割法 |
JPH0684332B2 (ja) * | 1985-06-20 | 1994-10-26 | 住友化学工業株式会社 | a−イソプロピル−p−クロルフエニル酢酸の光学分割法 |
JPS63227543A (ja) * | 1987-03-17 | 1988-09-21 | Nippon Kayaku Co Ltd | 光学活性2−(6−メトキシ−2−ナフチル)プロピオン酸の製造法 |
US5011989A (en) * | 1987-10-09 | 1991-04-30 | Sumitomo Chemical Company, Limited | Optically active hydroxybenzylamine |
DE3824353A1 (de) * | 1988-07-19 | 1990-01-25 | Paz Arzneimittelentwicklung | Verfahren zur trennung von gemischen enantiomerer arylpropionsaeuren |
US5191112A (en) * | 1989-10-17 | 1993-03-02 | Nissan Chemical Industries, Ltd. | Process for optical resolution of (±)-2-(3-benzoyl)-phenylpropionic acid |
US5015764A (en) * | 1990-06-18 | 1991-05-14 | Ethyl Corporation | Preparation of optically active aliphatic carboxylic acids |
-
1992
- 1992-07-29 CA CA002074932A patent/CA2074932A1/en not_active Abandoned
- 1992-07-31 US US07/922,393 patent/US5321154A/en not_active Expired - Fee Related
- 1992-08-05 DK DK92307140.1T patent/DK0529835T3/da active
- 1992-08-05 DE DE69216952T patent/DE69216952T2/de not_active Expired - Fee Related
- 1992-08-05 ES ES92307140T patent/ES2096724T3/es not_active Expired - Lifetime
- 1992-08-05 EP EP92307140A patent/EP0529835B1/en not_active Expired - Lifetime
- 1992-08-05 AT AT92307140T patent/ATE148089T1/de active
- 1992-08-20 JP JP04245590A patent/JP3135696B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0529835A2 (en) | 1993-03-03 |
ATE148089T1 (de) | 1997-02-15 |
DK0529835T3 (da) | 1997-06-30 |
CA2074932A1 (en) | 1993-02-24 |
EP0529835A3 (en) | 1993-04-28 |
DE69216952T2 (de) | 1997-07-10 |
DE69216952D1 (de) | 1997-03-06 |
JP3135696B2 (ja) | 2001-02-19 |
US5321154A (en) | 1994-06-14 |
EP0529835B1 (en) | 1997-01-22 |
JPH05229986A (ja) | 1993-09-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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