ES2092445A1 - Tensioactivos cationicos geminales del tipo n n bis (n-acil-arginina)a, w diamino alquil diclorhidratos como agentes antimicrobinos. - Google Patents

Tensioactivos cationicos geminales del tipo n n bis (n-acil-arginina)a, w diamino alquil diclorhidratos como agentes antimicrobinos.

Info

Publication number
ES2092445A1
ES2092445A1 ES09500265A ES9500265A ES2092445A1 ES 2092445 A1 ES2092445 A1 ES 2092445A1 ES 09500265 A ES09500265 A ES 09500265A ES 9500265 A ES9500265 A ES 9500265A ES 2092445 A1 ES2092445 A1 ES 2092445A1
Authority
ES
Spain
Prior art keywords
alpha
omega
arginin
antimicrobial agents
dichlorohydrates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09500265A
Other languages
English (en)
Other versions
ES2092445B1 (es
Inventor
Rosa Infante
Lourdes Perez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Consejo Superior de Investigaciones Cientificas CSIC
Original Assignee
Consejo Superior de Investigaciones Cientificas CSIC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ES09500265A priority Critical patent/ES2092445B1/es
Application filed by Consejo Superior de Investigaciones Cientificas CSIC filed Critical Consejo Superior de Investigaciones Cientificas CSIC
Priority to US08/718,533 priority patent/US5994406A/en
Priority to CA002187508A priority patent/CA2187508C/en
Priority to EP96901808A priority patent/EP0769491B1/en
Priority to ES96901808T priority patent/ES2153089T3/es
Priority to AT96901808T priority patent/ATE197039T1/de
Priority to PT96901808T priority patent/PT769491E/pt
Priority to DE69610680T priority patent/DE69610680T2/de
Priority to PCT/ES1996/000026 priority patent/WO1996024578A1/es
Priority to DK96901808T priority patent/DK0769491T3/da
Publication of ES2092445A1 publication Critical patent/ES2092445A1/es
Application granted granted Critical
Publication of ES2092445B1 publication Critical patent/ES2092445B1/es
Priority to GR20010400074T priority patent/GR3035254T3/el
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
    • A01N47/44—Guanidine; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Cosmetics (AREA)

Abstract

TENSIOACTIVOS CATIONICOS GEMINALES DEL TIPO NALNOE BIS (NAL-ACIL-ARGININA)AL,OE DIAMINO ALQUIL DICLORHIDRATOS COMO AGENTES ANTIMICROBIANOS, DE FORMULA GENERAL *FIG* X = 8-14; N = 2-8. SU PROCEDIMIENTO DE OBTENCION SIGUE LAS ETAPAS SIGUIENTES: A) FORMACION DE NITROARGININA; B) FORMACION DE NAL-ACIL-NITROARGININA; C) FORMACION DE NAL, NOE, BIS(NAL-ACIL-ARGININA)AL,OE DIAMINOALQUILAMIDA DICLORHIDRATO. SON TENSIOACTIVOS CON APLICACION ANTIMICROBIANA: COSMETICA, FARMACIA, ALIMENTACION.
ES09500265A 1995-02-09 1995-02-09 Tensioactivos cationicos geminales del tipo n n bis (n-acil-arginina)alfa, alfa damino alquil diclorhidratos como agentes antimicrobianos. Expired - Fee Related ES2092445B1 (es)

Priority Applications (11)

Application Number Priority Date Filing Date Title
ES09500265A ES2092445B1 (es) 1995-02-09 1995-02-09 Tensioactivos cationicos geminales del tipo n n bis (n-acil-arginina)alfa, alfa damino alquil diclorhidratos como agentes antimicrobianos.
PCT/ES1996/000026 WO1996024578A1 (es) 1995-02-09 1996-02-08 TENSIOACTIVOS CATIONICOS GEMINALES DEL TIPO N?αNφ BIS(Nα¿-ACIL-ARGININA)α,φ DIAMINO ALQUIL DICLORHIDRATOS COME AGENTES ANTIMICROBIANOS
EP96901808A EP0769491B1 (en) 1995-02-09 1996-02-08 Geminal cationic surfactants of the type n alpha n omega bis(n alpha-acyl-arginin) alpha, omega diamino alkyl dichlorohydrates as antimicrobial agents
ES96901808T ES2153089T3 (es) 1995-02-09 1996-02-08 Tensioactivos cationicos geminales del tipo n alfa n omega bis (n alfa-acil-arginina) alfa omega diamino alquil diclorhidratos como agentes antimicrobianos.
AT96901808T ATE197039T1 (de) 1995-02-09 1996-02-08 Geminale kationische oberflächenaktive mittel des typs n alpha n omega bis(n alpha-acyl-arginin) alpha, omega-diaminoalkyl-dichlorhydrate als antimikrobielle mittel
PT96901808T PT769491E (pt) 1995-02-09 1996-02-08 Agentes tensioactivos actionicos geminais do tipo dicloridrato alfa,omega-diaminoalquilico de n alfa,n omega-bis(n alfa-acil-arginina) enquanto agentes antimicrobianos
US08/718,533 US5994406A (en) 1995-02-09 1996-02-08 Geminal cationic surfactants of the type Nα Nω bis (Nα-acyl-arginin) α,ω diamino alkyl dichlorohydrates as antimicrobial agents
CA002187508A CA2187508C (en) 1995-02-09 1996-02-08 Geminal cationic surfactants of the type n.alpha.,n.omega.- bis(n.alpha.-acyl-arginine)-.alpha.,.omega.-diamino-alkyl-dichlorohydrates as anti- microbial agents
DK96901808T DK0769491T3 (da) 1995-02-09 1996-02-08 Geminale kationiske overfladeaktive midler af typen N alfa, N omega-bis(N alfa-acyl-arginin)alfa,omega-alkylendiamindihydro
DE69610680T DE69610680T2 (de) 1995-02-09 1996-02-08 Geminale kationische oberflächenaktive mittel des typs n alpha n omega bis(n alpha-acyl-arginin) alpha, omega-diaminoalkyl-dichlorhydrate als antimikrobielle mittel
GR20010400074T GR3035254T3 (en) 1995-02-09 2001-01-17 Geminal cationic surfactants of the type n alpha n omega bis(n alpha-acyl-arginin) alpha, omega diamino alkyl dichlorohydrates as antimicrobial agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09500265A ES2092445B1 (es) 1995-02-09 1995-02-09 Tensioactivos cationicos geminales del tipo n n bis (n-acil-arginina)alfa, alfa damino alquil diclorhidratos como agentes antimicrobianos.

Publications (2)

Publication Number Publication Date
ES2092445A1 true ES2092445A1 (es) 1996-11-16
ES2092445B1 ES2092445B1 (es) 1997-07-01

Family

ID=8289436

Family Applications (2)

Application Number Title Priority Date Filing Date
ES09500265A Expired - Fee Related ES2092445B1 (es) 1995-02-09 1995-02-09 Tensioactivos cationicos geminales del tipo n n bis (n-acil-arginina)alfa, alfa damino alquil diclorhidratos como agentes antimicrobianos.
ES96901808T Expired - Lifetime ES2153089T3 (es) 1995-02-09 1996-02-08 Tensioactivos cationicos geminales del tipo n alfa n omega bis (n alfa-acil-arginina) alfa omega diamino alquil diclorhidratos como agentes antimicrobianos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES96901808T Expired - Lifetime ES2153089T3 (es) 1995-02-09 1996-02-08 Tensioactivos cationicos geminales del tipo n alfa n omega bis (n alfa-acil-arginina) alfa omega diamino alquil diclorhidratos como agentes antimicrobianos.

Country Status (10)

Country Link
US (1) US5994406A (es)
EP (1) EP0769491B1 (es)
AT (1) ATE197039T1 (es)
CA (1) CA2187508C (es)
DE (1) DE69610680T2 (es)
DK (1) DK0769491T3 (es)
ES (2) ES2092445B1 (es)
GR (1) GR3035254T3 (es)
PT (1) PT769491E (es)
WO (1) WO1996024578A1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2163352A1 (es) * 1999-04-09 2002-01-16 Consejo Superior Investigacion Procedimiento enzimatico para la preparacion de los tensioactivos cationicos geminales del tipo nalfa,nomega,bis(nalfa-acil-arginina)alfa,omegaalcanodiamidas diclorhidrato en medios con bajo contenido acuoso.

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2163368B1 (es) 2000-02-11 2003-04-01 Consejo Superior Investigacion Tensioactivos del tipo 1-o-l-arginil ester 3-o-monoacil gliceridos y 1-o-l-arginil ester 2,3-o-diacil gliceridos.

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3825560A (en) * 1969-12-30 1974-07-23 Y Sasaki N-monoacyl derivatives of arginine
ES8303312A1 (es) * 1982-05-28 1983-02-16 Consejo Superior Investigacion "nuevo procedimiento para la preparacion de acidos n-acil-l-alquilaminoguanidinicos y cualquiera de sus sales, como agentes tensioactivos de accion antimicrobiana".
ES2020148A6 (es) * 1990-06-07 1991-07-16 Consejo Superior Investigacion Procedimiento para la sintesis de dipeptidos de n-alfa-acil arginina de cadena grasa y amino-acidos puros como tensioactivos ionicos de accion antimicrobiana.
WO1993016991A1 (es) * 1992-02-28 1993-09-02 Consejo Superior Investigaciones Científicas Tensioactivos cationicos que contienen en su molecula un grupo disulfuro, su procedimiento de obtencion

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3825560A (en) * 1969-12-30 1974-07-23 Y Sasaki N-monoacyl derivatives of arginine
ES8303312A1 (es) * 1982-05-28 1983-02-16 Consejo Superior Investigacion "nuevo procedimiento para la preparacion de acidos n-acil-l-alquilaminoguanidinicos y cualquiera de sus sales, como agentes tensioactivos de accion antimicrobiana".
ES2020148A6 (es) * 1990-06-07 1991-07-16 Consejo Superior Investigacion Procedimiento para la sintesis de dipeptidos de n-alfa-acil arginina de cadena grasa y amino-acidos puros como tensioactivos ionicos de accion antimicrobiana.
WO1993016991A1 (es) * 1992-02-28 1993-09-02 Consejo Superior Investigaciones Científicas Tensioactivos cationicos que contienen en su molecula un grupo disulfuro, su procedimiento de obtencion

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2163352A1 (es) * 1999-04-09 2002-01-16 Consejo Superior Investigacion Procedimiento enzimatico para la preparacion de los tensioactivos cationicos geminales del tipo nalfa,nomega,bis(nalfa-acil-arginina)alfa,omegaalcanodiamidas diclorhidrato en medios con bajo contenido acuoso.

Also Published As

Publication number Publication date
EP0769491A1 (en) 1997-04-23
PT769491E (pt) 2001-04-30
CA2187508C (en) 2008-09-23
CA2187508A1 (en) 1996-08-15
GR3035254T3 (en) 2001-04-30
DK0769491T3 (da) 2001-02-26
ATE197039T1 (de) 2000-11-15
ES2092445B1 (es) 1997-07-01
EP0769491B1 (en) 2000-10-18
DE69610680T2 (de) 2001-05-10
WO1996024578A1 (es) 1996-08-15
DE69610680D1 (de) 2000-11-23
US5994406A (en) 1999-11-30
ES2153089T3 (es) 2001-02-16

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