ES2090344T3 - Procedimiento para la preparacion de derivados de beta-carbolina. - Google Patents

Procedimiento para la preparacion de derivados de beta-carbolina.

Info

Publication number
ES2090344T3
ES2090344T3 ES91913362T ES91913362T ES2090344T3 ES 2090344 T3 ES2090344 T3 ES 2090344T3 ES 91913362 T ES91913362 T ES 91913362T ES 91913362 T ES91913362 T ES 91913362T ES 2090344 T3 ES2090344 T3 ES 2090344T3
Authority
ES
Spain
Prior art keywords
beta
pct
carboline derivatives
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91913362T
Other languages
English (en)
Inventor
Alfred Dr Weber
Mario Dr Kennecke
Jean-Claude Dr Hilscher
Klaus Dr Nickisch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of ES2090344T3 publication Critical patent/ES2090344T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA LA PRODUCCION DE DERIVADOS (BETA) RBOLINICOS. UN PROCEDIMIENTO PARA LA PRODUCCION DE DERIVADOS (BETA) CARBOLINICOS DE LA FORMULA GENERAL, EN DONDE X REPRESENTA UN ATOMO DE HIDROGENO O UN ATOMO HALOGENO, Y UN ENLACE CARBONO-OXIGENO O UN GRUPO METILO, R1 UN GRUPO ALQUILO CON HASTA 6 ATOMOS DE CARBONO Y R2 UN GRUPO ALQUILO CON HASTA 4 ATOMOS DE CARBONO, A PARTIR DE DERIVADOS 1,2,3,4 NICOS DE LA FORMULA GENERAL, EN DONDE X, Y, R1 Y R2 POSEEN EL SIGNIFICADO ANTERIOR. EL PROCESO SE CARACTERIZA POR QUE LOS DERIVADOS 1,2,3,4 TAN CON UN CULTIVO DE HONGOS DEL TIPO FUSARIUM O MIROTECIUM.
ES91913362T 1990-09-13 1991-08-01 Procedimiento para la preparacion de derivados de beta-carbolina. Expired - Lifetime ES2090344T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4029389A DE4029389A1 (de) 1990-09-13 1990-09-13 Verfahren zur herstellung von (beta)-carbolin-derivaten

Publications (1)

Publication Number Publication Date
ES2090344T3 true ES2090344T3 (es) 1996-10-16

Family

ID=6414378

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91913362T Expired - Lifetime ES2090344T3 (es) 1990-09-13 1991-08-01 Procedimiento para la preparacion de derivados de beta-carbolina.

Country Status (11)

Country Link
US (1) US5258290A (es)
EP (1) EP0505514B1 (es)
AT (1) ATE138415T1 (es)
CA (1) CA2073690A1 (es)
DE (2) DE4029389A1 (es)
DK (1) DK0505514T3 (es)
ES (1) ES2090344T3 (es)
FI (1) FI97974C (es)
GR (1) GR3020844T3 (es)
MX (1) MX9101013A (es)
WO (1) WO1992005269A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4240672A1 (de) * 1992-11-24 1994-05-26 Schering Ag Neues Verfahren zur Herstellung von beta-Carbolinen
JPH06225793A (ja) * 1992-11-27 1994-08-16 Nippon Kayaku Co Ltd 6β,14α−ジヒドロキシ−4−アンドロステン−3,17−ジオンの新規製造法
AU2003258395A1 (en) * 2002-08-30 2004-03-19 Puratos Naamloze Vennootschap Myrothecium sp. transformation and expression system

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ194747A (en) * 1979-08-29 1988-11-29 Schering Ag 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
DE3240514A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Ss-carboline, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3322895A1 (de) * 1983-06-23 1985-01-03 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ss-carboline, verfahren zur ihrer herstellung und ihre verwendung als arzneimittel (s)
DE3504045A1 (de) * 1985-02-04 1986-08-07 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von ss-carbolinen durch dehydrierung
DE3540654A1 (de) * 1985-11-13 1987-05-14 Schering Ag Phenoxy-substituierte ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
DE59107846D1 (de) 1996-06-27
FI922174A (fi) 1992-05-13
FI922174A0 (fi) 1992-05-13
MX9101013A (es) 1992-08-10
WO1992005269A1 (de) 1992-04-02
EP0505514A1 (de) 1992-09-30
EP0505514B1 (de) 1996-05-22
FI97974B (fi) 1996-12-13
CA2073690A1 (en) 1992-03-14
DE4029389A1 (de) 1992-03-26
DK0505514T3 (da) 1996-10-07
US5258290A (en) 1993-11-02
FI97974C (fi) 1997-03-25
GR3020844T3 (en) 1996-11-30
ATE138415T1 (de) 1996-06-15

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