ES2088752B1 - LIPOSOMES SPECIFIC FOR THE ELIMINATION OF HIV AND CELLS INFECTED BY THE SAME. - Google Patents

LIPOSOMES SPECIFIC FOR THE ELIMINATION OF HIV AND CELLS INFECTED BY THE SAME.

Info

Publication number
ES2088752B1
ES2088752B1 ES9500161A ES9500161A ES2088752B1 ES 2088752 B1 ES2088752 B1 ES 2088752B1 ES 9500161 A ES9500161 A ES 9500161A ES 9500161 A ES9500161 A ES 9500161A ES 2088752 B1 ES2088752 B1 ES 2088752B1
Authority
ES
Spain
Prior art keywords
hiv
elimination
liposomes
protease
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9500161A
Other languages
Spanish (es)
Other versions
ES2088752A1 (en
Inventor
Mu Oz Teodoro Palomino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to ES9500161A priority Critical patent/ES2088752B1/en
Priority to PCT/ES1996/000014 priority patent/WO1996022763A1/en
Priority to AU45404/96A priority patent/AU4540496A/en
Priority to EP96901350A priority patent/EP0754451A1/en
Publication of ES2088752A1 publication Critical patent/ES2088752A1/en
Application granted granted Critical
Publication of ES2088752B1 publication Critical patent/ES2088752B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

LIPOSOMAS ESPECIFICOS PARA LA ELIMINACION DE VIH Y CELULAS INFECTADAS POR EL MISMO. LIPOSOMAS CON MOLECULAS DE CD4 ADSORBIDAS EN SU SUPERFICIE, QUE LLEVAN EN SU INTERIOR UNA PROTEASA (EJEMPLO TRIPSINA) O BIEN UNA RNASA (EJEMPLO RIBONUCLEASA T) Y QUE SON ESPECIFICOS PARA LA ELIMINACION DE VIH Y DE LAS CELULAS INFECTADAS POR EL MISMO. CUANDO UN LIPOSOMA CARGADO CON PROTEASA HACE COALESCENCIA CON UNA PARTICULA VIH LA PROTEASA DESTRUYE SU NUCLEOCAPSIDE; SI EL LIPOSOMA CONTIENE RIBONUCLEASA, ESTA DESTRUYE EL RNA VIRICO. LAS CELULAS INFECTADAS (PORTADORAS DE PG120) SON DESTRUIDAS AL HACER COALESCENCIA CON LIPOSOMAS CON PROTEASA ENCAPSULADA.LIPOSOMES SPECIFIC FOR THE ELIMINATION OF HIV AND CELLS INFECTED BY THE SAME. LIPOSOMES WITH ADSORBED CD4 MOLECULES ON THEIR SURFACE, WHICH CARRY A PROTEASE (EXAMPLE TRIPSIN) OR A RNASA (EXAMPLE RIBONUCLEASE T) AND THAT ARE SPECIFIC FOR THE ELIMINATION OF HIV AND OF THE INFECTED CELLS. WHEN A LIPOSOMA CHARGED WITH PROTEASE COALESCENTS WITH A PARTICLE HIV, PROTEASE DESTROYS ITS NUCLEOCAPSIDE; IF THE LIPOSOMA CONTAINS RIBONUCLEASE, IT DESTROYS THE VIRUS RNA. INFECTED CELLS (CARRIERS OF PG120) ARE DESTROYED BY COALESCENCE WITH LIPOSOMES WITH ENCAPSULATED PROTEASE.

ES9500161A 1995-01-27 1995-01-27 LIPOSOMES SPECIFIC FOR THE ELIMINATION OF HIV AND CELLS INFECTED BY THE SAME. Expired - Fee Related ES2088752B1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
ES9500161A ES2088752B1 (en) 1995-01-27 1995-01-27 LIPOSOMES SPECIFIC FOR THE ELIMINATION OF HIV AND CELLS INFECTED BY THE SAME.
PCT/ES1996/000014 WO1996022763A1 (en) 1995-01-27 1996-01-26 Liposome for destroying hiv and cells infected by said virus
AU45404/96A AU4540496A (en) 1995-01-27 1996-01-26 Liposome for destroying hiv and cells infected by said virus
EP96901350A EP0754451A1 (en) 1995-01-27 1996-01-26 Liposome for destroying hiv and cells infected by said virus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9500161A ES2088752B1 (en) 1995-01-27 1995-01-27 LIPOSOMES SPECIFIC FOR THE ELIMINATION OF HIV AND CELLS INFECTED BY THE SAME.

Publications (2)

Publication Number Publication Date
ES2088752A1 ES2088752A1 (en) 1996-08-16
ES2088752B1 true ES2088752B1 (en) 1997-03-01

Family

ID=8289296

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9500161A Expired - Fee Related ES2088752B1 (en) 1995-01-27 1995-01-27 LIPOSOMES SPECIFIC FOR THE ELIMINATION OF HIV AND CELLS INFECTED BY THE SAME.

Country Status (1)

Country Link
ES (1) ES2088752B1 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223263A (en) * 1988-07-07 1993-06-29 Vical, Inc. Liponucleotide-containing liposomes
DE3711724A1 (en) * 1987-04-07 1988-10-20 Harro Boerner Medizinische Kom System for acting on, in particular destroying, viruses

Also Published As

Publication number Publication date
ES2088752A1 (en) 1996-08-16

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