ES2084150T3 - Aminoacidos, peptidos o sus derivados asociados a las grasas. - Google Patents
Aminoacidos, peptidos o sus derivados asociados a las grasas.Info
- Publication number
- ES2084150T3 ES2084150T3 ES91901249T ES91901249T ES2084150T3 ES 2084150 T3 ES2084150 T3 ES 2084150T3 ES 91901249 T ES91901249 T ES 91901249T ES 91901249 T ES91901249 T ES 91901249T ES 2084150 T3 ES2084150 T3 ES 2084150T3
- Authority
- ES
- Spain
- Prior art keywords
- peptides
- amino acids
- derivative
- fats
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/08—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06043—Leu-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
Abstract
AMINOACIDOS, PEPTIDOS O DERIVADOS DE LOS MISMOS ACOPLADOS A GRASAS LA PRESENTE INVENCION PRESENTA NUEVOS COMPUESTOS EN QUE PEPTIDOS, AMINOACIDOS O DERIVADOS DE LOS MISMOS ESTAN ENLAZADOS A OTRAS MOLECULAS, EN PARTICULAR A ACIDOS GRASOS, LO QUE FACILITA EL USO DE TALES PEPTIDOS, AMINOACIDOS Y DERIVADOS DE LOS MISMOS. LA ESTRUCTURA BASICA DE LOS COMPUESTOS DE LA PRESENTE INVENCION ES UN AMINOACIDO, PEPTIDO O DERIVADO DE LOS MISMOS ENLAZADOS A 1, 2 O 3 MOLECULAS DE UN ACIDO GRASO MEDIANTE UN DERIVADO DE TROMETAMINA. ALTERNATIVAMENTE, EL AMINOACIDO, PEPTIDO O DERIVADO DE LOS MISMOS PUEDE ESTAR ENLAZADO A UN ACIDO GRASO MEDIANTE UN DERIVADO DE ETANOLAMINA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPJ803589 | 1989-12-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2084150T3 true ES2084150T3 (es) | 1996-05-01 |
Family
ID=3774435
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91901249T Expired - Lifetime ES2084150T3 (es) | 1989-12-22 | 1990-12-19 | Aminoacidos, peptidos o sus derivados asociados a las grasas. |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0506748B1 (es) |
AT (1) | ATE131471T1 (es) |
DE (1) | DE69024230T2 (es) |
DK (1) | DK0506748T3 (es) |
ES (1) | ES2084150T3 (es) |
GR (1) | GR3018691T3 (es) |
WO (1) | WO1991009837A1 (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5206027A (en) * | 1990-09-13 | 1993-04-27 | Fuji Photo Film Co., Ltd. | Amphipathic compound and liposome comprising the same |
US5554728A (en) * | 1991-07-23 | 1996-09-10 | Nexstar Pharmaceuticals, Inc. | Lipid conjugates of therapeutic peptides and protease inhibitors |
US5955080A (en) * | 1991-07-26 | 1999-09-21 | Commonwealth Scientific And Industrial Research Organisation | Self-adjuvanting peptide vaccine delivery system and production thereof |
SE9302296D0 (sv) * | 1993-07-02 | 1993-07-02 | Kabi Pharmacia Ab | Amino acid supplement |
JPH09501655A (ja) | 1993-08-02 | 1997-02-18 | コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガニゼーション | 治療化合物−脂肪酸接合体 |
SI9420051A (en) * | 1993-08-09 | 1996-12-31 | Biomeasure Inc | Chemical modified peptide derivatives, process for their preparation and their use in human therapy |
DE4437502A1 (de) * | 1993-12-02 | 1995-06-08 | Basf Ag | Hirudin-Konjugate aus Hirudin und lipophilen Verbindungen |
AUPM747694A0 (en) * | 1994-08-16 | 1994-09-08 | Commonwealth Scientific And Industrial Research Organisation | Delivery of nucleic acids and peptides |
NZ298712A (en) * | 1995-01-16 | 1998-12-23 | Commw Scient Ind Res Org | Fatty acid acyl group conjugates as therapeutic compounds |
US6248713B1 (en) | 1995-07-11 | 2001-06-19 | Biogen, Inc. | Cell adhesion inhibitors |
AUPN741696A0 (en) * | 1996-01-05 | 1996-01-25 | Commonwealth Scientific And Industrial Research Organisation | Delivery of nucleic acids ii |
DE19605175A1 (de) * | 1996-02-13 | 1997-08-14 | Sourovoi Andrej Dr | Lipidverbindungen und deren Verwendung |
US6239108B1 (en) | 1996-07-11 | 2001-05-29 | Biogen, Inc. | Cell adhesion inhibitors |
DE69737769T2 (de) | 1996-07-25 | 2008-05-15 | Biogen Idec Ma Inc., Cambridge | Molekülmodell für vla-4-inhibitoren |
US6686350B1 (en) | 1996-07-25 | 2004-02-03 | Biogen, Inc. | Cell adhesion inhibitors |
AUPP051497A0 (en) * | 1997-11-24 | 1997-12-18 | University Of Melbourne, The | Antimicrobial peptides |
NZ509199A (en) | 1998-05-28 | 2003-10-31 | Biogen Inc | A VLA-4 inhibitor: oMePUPA-V |
CZ2002518A3 (cs) | 1999-08-13 | 2002-05-15 | Biogen, Inc. | Inhibitory buněčné adheze a farmaceutické prostředky, které je obsahují |
US6875743B1 (en) | 2000-11-28 | 2005-04-05 | Biogen, Inc. | Cell adhesion inhibitors |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
AU2004298285B2 (en) | 2003-12-19 | 2010-06-24 | Dairy Australia Limited | Antimicrobial composition |
US7196112B2 (en) | 2004-07-16 | 2007-03-27 | Biogen Idec Ma Inc. | Cell adhesion inhibitors |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1986004894A1 (en) * | 1985-02-15 | 1986-08-28 | Takeda Chemical Industries, Ltd. | Lipid derivatives |
WO1985004398A1 (en) * | 1984-04-03 | 1985-10-10 | Takeda Chemical Industries, Ltd. | Lipid derivatives |
US4751219A (en) * | 1985-02-05 | 1988-06-14 | Nederlandse Centrale Organisatie Voor Toegepast-Natuur-Wetenschappelijk Onderzoek | Synthetic glycolipides, a process for the preparation thereof and several uses for these synthetic glycolipides |
DE3627924A1 (de) | 1986-08-18 | 1988-03-03 | Henkel Kgaa | Verwendung von aminofettsaeureamiden als vernetzungsmittel |
DE3801587A1 (de) * | 1988-01-21 | 1989-08-03 | Hoechst Ag | Neue aminosaeureglyceride, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung |
JPH03502328A (ja) | 1988-02-01 | 1991-05-30 | ジ・アップジョン・カンパニー | 極性末端基類を有するレニン抑制ペプチド類 |
GB2217319A (en) * | 1988-04-19 | 1989-10-25 | Synpharm Ltd | Racemic and optically active fatty amino acids, their homo- abd hetero-oligomers and conjugates, the process of their production, their pharmaceutical composi |
-
1990
- 1990-12-19 EP EP91901249A patent/EP0506748B1/en not_active Expired - Lifetime
- 1990-12-19 DE DE69024230T patent/DE69024230T2/de not_active Expired - Fee Related
- 1990-12-19 ES ES91901249T patent/ES2084150T3/es not_active Expired - Lifetime
- 1990-12-19 WO PCT/AU1990/000599 patent/WO1991009837A1/en active IP Right Grant
- 1990-12-19 DK DK91901249.2T patent/DK0506748T3/da active
- 1990-12-19 AT AT91901249T patent/ATE131471T1/de not_active IP Right Cessation
-
1996
- 1996-01-17 GR GR960400092T patent/GR3018691T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE69024230T2 (de) | 1996-05-02 |
EP0506748A4 (en) | 1992-12-02 |
EP0506748B1 (en) | 1995-12-13 |
DK0506748T3 (da) | 1996-01-22 |
DE69024230D1 (de) | 1996-01-25 |
AU649242B2 (en) | 1994-05-19 |
AU7033691A (en) | 1991-07-24 |
GR3018691T3 (en) | 1996-04-30 |
WO1991009837A1 (en) | 1991-07-11 |
ATE131471T1 (de) | 1995-12-15 |
EP0506748A1 (en) | 1992-10-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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