ES2084030T3 - Expresion del fragmento c de la toxina del tetanos - Google Patents

Expresion del fragmento c de la toxina del tetanos

Info

Publication number
ES2084030T3
ES2084030T3 ES90909052T ES90909052T ES2084030T3 ES 2084030 T3 ES2084030 T3 ES 2084030T3 ES 90909052 T ES90909052 T ES 90909052T ES 90909052 T ES90909052 T ES 90909052T ES 2084030 T3 ES2084030 T3 ES 2084030T3
Authority
ES
Spain
Prior art keywords
fragment
expression
tetanus toxin
tetanus
toxin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90909052T
Other languages
English (en)
Inventor
Neil Fraser Fairweather
Andrew Joseph Makoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB Pharma Ltd
Original Assignee
Evans Medical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evans Medical Ltd filed Critical Evans Medical Ltd
Application granted granted Critical
Publication of ES2084030T3 publication Critical patent/ES2084030T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

UN PROCESO PARA LA PRODUCCION DEL FRAGMENTO C DE LA TOXINA DEL TETANOS.
ES90909052T 1989-06-20 1990-06-20 Expresion del fragmento c de la toxina del tetanos Expired - Lifetime ES2084030T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898914122A GB8914122D0 (en) 1989-06-20 1989-06-20 Polypeptide expression

Publications (1)

Publication Number Publication Date
ES2084030T3 true ES2084030T3 (es) 1996-05-01

Family

ID=10658724

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90909052T Expired - Lifetime ES2084030T3 (es) 1989-06-20 1990-06-20 Expresion del fragmento c de la toxina del tetanos

Country Status (9)

Country Link
US (1) US5443966A (es)
EP (1) EP0478602B1 (es)
JP (1) JP2981286B2 (es)
AT (1) ATE132532T1 (es)
DE (1) DE69024652T2 (es)
DK (1) DK0478602T3 (es)
ES (1) ES2084030T3 (es)
GB (1) GB8914122D0 (es)
WO (1) WO1990015871A1 (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5601826A (en) * 1989-06-30 1997-02-11 The United States Of America As Represented By The Department Of Health And Human Services Peptide which produces protective immunity against tetanus
GB9209118D0 (en) * 1992-04-28 1992-06-10 Sb 120 Amsterdam Bv Vaccine compositions
WO1994000487A1 (en) * 1992-06-30 1994-01-06 The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Peptide which produces protective immunity against tetanus
KR950702635A (ko) 1992-07-31 1995-07-29 크리스틴 헬렌 수덴 감쇠 박테리아에서 재조합 융합 단백질의 발현(Expression of recombinant fusion proteins in attenuated bacteria)
GB9401787D0 (en) * 1994-01-31 1994-03-23 Medeva Holdings Bv Vaccine compositions
US20030185792A1 (en) * 1996-01-22 2003-10-02 Curis, Inc. Morphogen analogs of bone morphogenic proteins
EP0876401B1 (en) * 1996-01-22 2007-06-13 Curis, Inc. Methods for producing op-1 morphogen analogs
JP4229341B2 (ja) * 1996-03-23 2009-02-25 財団法人阪大微生物病研究会 破傷風毒素の機能的フラグメント抗原及び破傷風ワクチン
US5958469A (en) * 1997-05-14 1999-09-28 Eastman Kodak Company Method for fabricating tools for molding diffractive surfaces on optical lenses
US20100081197A1 (en) * 1997-08-14 2010-04-01 Sylvie Roux In vivo modulation of neuronal transport
US7923216B2 (en) 1997-08-14 2011-04-12 Institut Pasteur In vivo modulation of neuronal transport
DE69836982T2 (de) * 1997-08-14 2007-10-31 Institut Pasteur Hybride Tetanustoxinproteine die retrograd und transsynaptisch ins ZNS migrieren
GB0108364D0 (en) 2001-04-03 2001-05-23 Glaxosmithkline Biolog Sa Vaccine composition
CA2783274C (en) 2000-06-29 2018-08-07 Glaxosmithkline Biologicals S.A. Multivalent vaccine composition with reduced dose of haemophilus influenza type b
US20070105799A1 (en) * 2002-09-10 2007-05-10 Vical Incorporated Codon-optimized polynucleotide-based vaccines against Bacillus anthracis infection
US7972608B2 (en) * 2003-06-23 2011-07-05 Baxter International Inc. Carrier proteins for vaccines
US20070092449A1 (en) * 2005-04-05 2007-04-26 Rafael Vazquez-Martinez Methods for direct visualization of active synapses
EP1790358A1 (en) * 2005-11-23 2007-05-30 Université de Reims Champagne-Ardennes Protein constructs designed for targeting and lysis of cells
PL2097102T3 (pl) 2006-09-07 2012-10-31 Glaxosmithkline Biologicals Sa Szczepionka skojarzona o zmniejszonej ilości antygenu wirusa polio
TW200914042A (en) 2007-05-02 2009-04-01 Glaxosmithkline Biolog Sa Vaccine
EP2553102B1 (en) 2010-03-30 2015-12-09 Pfenex Inc. High level expression of recombinant toxin proteins
WO2011143557A2 (en) 2010-05-14 2011-11-17 The Children's Hospital Of Philadelphia Humanized ttc and methods of use thereof
GB201105981D0 (en) 2011-04-08 2011-05-18 Glaxosmithkline Biolog Sa Novel process
DK2788021T3 (en) 2011-12-09 2017-04-10 Bavarian Nordic As POXVIRUS VECTOR FOR EXPRESSION OF BACTERIAL ANTIGENES CONNECTED TO TETANANOX INFRAGMENT C
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
ES2597832T3 (es) 2013-03-08 2017-01-23 Janssen Vaccines & Prevention B.V. Vacuna acelular contra la tosferina
EP3164149A1 (en) 2014-07-02 2017-05-10 Spherium Biomed S.L. Methods of increasing muscle mass using non-toxic tetanus toxin c fragment (ttc)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2355094C3 (de) * 1973-11-03 1979-05-23 Behringwerke Ag, 3550 Marburg Verfahren zur Herstellung eines Tetanus-Impfstoffs
GB8516442D0 (en) * 1985-06-28 1985-07-31 Wellcome Found Cloned antigen

Also Published As

Publication number Publication date
DE69024652T2 (de) 1996-05-15
DK0478602T3 (da) 1996-02-05
DE69024652D1 (de) 1996-02-15
WO1990015871A1 (en) 1990-12-27
EP0478602A1 (en) 1992-04-08
JP2981286B2 (ja) 1999-11-22
ATE132532T1 (de) 1996-01-15
EP0478602B1 (en) 1996-01-03
US5443966A (en) 1995-08-22
JPH04506005A (ja) 1992-10-22
GB8914122D0 (en) 1989-08-09

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