ES2083467T3 - Particulas de hidrogel macroporosas erosionables y preparacion de las mismas. - Google Patents

Particulas de hidrogel macroporosas erosionables y preparacion de las mismas.

Info

Publication number
ES2083467T3
ES2083467T3 ES90916604T ES90916604T ES2083467T3 ES 2083467 T3 ES2083467 T3 ES 2083467T3 ES 90916604 T ES90916604 T ES 90916604T ES 90916604 T ES90916604 T ES 90916604T ES 2083467 T3 ES2083467 T3 ES 2083467T3
Authority
ES
Spain
Prior art keywords
hydrogel particles
erosionable
preparation
macroporous hydrogel
active agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90916604T
Other languages
English (en)
Inventor
Robert P Eury
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Heron Therapeutics LLC
Original Assignee
Advanced Polymer Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Polymer Systems Inc filed Critical Advanced Polymer Systems Inc
Application granted granted Critical
Publication of ES2083467T3 publication Critical patent/ES2083467T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)

Abstract

LA PRESENTE INVENCION PRESENTA UN SISTEMA DE SUMINISTRO POLIMERICO PARA EL SUMINISTRO DE UNA VARIEDAD DE SUSTANCIAS ACTIVAS A UN ENTORNO ACUOSO. DE MANERA MAS PARTICULAR, ESTA DIRIGIDO A UN SISTEMA DE SUMINISTRO QUE COMPRENDE PARTICULAS DE HIDROGEL DESGASTABLES QUE CONTIENEN UNA RED SUSTANCIALMENTE CONTINUA DE POROS Y UN IMPREGNANTE QUE COMPRENDE UN AGENTE ACTIVO. SEGUN LA INVENCION, EL AGENTE ACTIVO SE INTRODUCE EN LA RED DE POROS DE LAS PARTICULAS DE HIDROGEL DESPUES DE HABER PREPARADO LAS PARTICULAS.
ES90916604T 1989-10-03 1990-09-28 Particulas de hidrogel macroporosas erosionables y preparacion de las mismas. Expired - Lifetime ES2083467T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41656789A 1989-10-03 1989-10-03

Publications (1)

Publication Number Publication Date
ES2083467T3 true ES2083467T3 (es) 1996-04-16

Family

ID=23650468

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90916604T Expired - Lifetime ES2083467T3 (es) 1989-10-03 1990-09-28 Particulas de hidrogel macroporosas erosionables y preparacion de las mismas.

Country Status (11)

Country Link
EP (1) EP0494996B1 (es)
JP (1) JP2980978B2 (es)
KR (1) KR920703016A (es)
AT (1) ATE131726T1 (es)
AU (1) AU646414B2 (es)
CA (1) CA2066594A1 (es)
DE (1) DE69024363T2 (es)
DK (1) DK0494996T3 (es)
ES (1) ES2083467T3 (es)
HK (1) HK1007109A1 (es)
WO (1) WO1991004732A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11510137A (ja) * 1995-07-28 1999-09-07 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 植物プランクトン用の微量栄養素を含有する水−浮遊性の粒状物質
US5851538A (en) * 1995-12-29 1998-12-22 Advanced Polymer Systems, Inc. Retinoid formulations in porous microspheres for reduced irritation and enhanced stability
US5985309A (en) * 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
US5874064A (en) * 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
USRE37053E1 (en) 1996-05-24 2001-02-13 Massachusetts Institute Of Technology Particles incorporating surfactants for pulmonary drug delivery
US6652837B1 (en) 1996-05-24 2003-11-25 Massachusetts Institute Of Technology Preparation of novel particles for inhalation
US6254854B1 (en) 1996-05-24 2001-07-03 The Penn Research Foundation Porous particles for deep lung delivery
US5855913A (en) * 1997-01-16 1999-01-05 Massachusetts Instite Of Technology Particles incorporating surfactants for pulmonary drug delivery
DE19622355A1 (de) 1996-06-04 1997-12-11 Bayer Ag Formkörper die agrochemische Mittel freisetzen
GB9621825D0 (en) * 1996-10-19 1996-12-11 Andaris Ltd Microparticles and their use as therapeutic vehicles
US20030008926A1 (en) * 1997-04-30 2003-01-09 Mcpartland Tor Ant spray containing D-limonene and methods of making and using same
US20020004502A1 (en) 2000-01-05 2002-01-10 Redmond H. Paul Treatment of inflammatory bowel disease
US6878384B2 (en) * 2001-03-13 2005-04-12 Microvention, Inc. Hydrogels that undergo volumetric expansion in response to changes in their environment and their methods of manufacture and use
EP2027729A2 (en) 2006-06-15 2009-02-25 MicroVention, Inc. Embolization device constructed from expansible polymer
BRPI0821070B1 (pt) 2007-12-21 2018-10-23 Microvention Inc dispositivo para implantação e método para a preparação de um filamento de hidrogel para implantação em um animal
WO2009108760A2 (en) * 2008-02-26 2009-09-03 Board Of Regents, The University Of Texas System Dendritic macroporous hydrogels prepared by crystal templating
CA2777171C (en) 2009-10-26 2017-09-19 Microvention, Inc. Embolization device constructed from expansile polymer
US9456823B2 (en) 2011-04-18 2016-10-04 Terumo Corporation Embolic devices
JP6599361B2 (ja) 2014-04-29 2019-10-30 マイクロベンション インコーポレイテッド 活性剤を含むポリマー
WO2016201250A1 (en) 2015-06-11 2016-12-15 Microvention, Inc. Expansile device for implantation
CN114384227A (zh) * 2021-06-16 2022-04-22 西安石油大学 一种致密砂岩的准连续溶蚀-胶结作用致密机理测定方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4818542A (en) * 1983-11-14 1989-04-04 The University Of Kentucky Research Foundation Porous microspheres for drug delivery and methods for making same
US4690825A (en) * 1985-10-04 1987-09-01 Advanced Polymer Systems, Inc. Method for delivering an active ingredient by controlled time release utilizing a novel delivery vehicle which can be prepared by a process utilizing the active ingredient as a porogen
EP0277211B1 (en) * 1986-08-15 1994-06-01 Advanced Polymer Systems, Inc. Polymeric carrier compositions and methods for their preparation and use
ZA886284B (en) * 1987-08-31 1990-04-25 Advanced Polymer Systems Inc Controlled release formulations
US4806360A (en) * 1987-10-23 1989-02-21 Advanced Polymer Systems Synthetic melanin aggregates

Also Published As

Publication number Publication date
JP2980978B2 (ja) 1999-11-22
CA2066594A1 (en) 1991-04-04
HK1007109A1 (en) 1999-04-01
DE69024363T2 (de) 1996-07-04
EP0494996A1 (en) 1992-07-22
EP0494996B1 (en) 1995-12-20
WO1991004732A1 (en) 1991-04-18
DK0494996T3 (da) 1996-03-18
JPH05500959A (ja) 1993-02-25
AU646414B2 (en) 1994-02-24
DE69024363D1 (de) 1996-02-01
EP0494996A4 (en) 1992-09-30
KR920703016A (ko) 1992-12-17
ATE131726T1 (de) 1996-01-15
AU6715690A (en) 1991-04-28

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