ES2079349T3 - Sales por adicion de acidos de cefem cristalizadas y procedimiento para su preparacion. - Google Patents

Sales por adicion de acidos de cefem cristalizadas y procedimiento para su preparacion.

Info

Publication number
ES2079349T3
ES2079349T3 ES88102230T ES88102230T ES2079349T3 ES 2079349 T3 ES2079349 T3 ES 2079349T3 ES 88102230 T ES88102230 T ES 88102230T ES 88102230 T ES88102230 T ES 88102230T ES 2079349 T3 ES2079349 T3 ES 2079349T3
Authority
ES
Spain
Prior art keywords
cefem
crystallized
salts
acids
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88102230T
Other languages
English (en)
Inventor
Rudolf Dr Lattrell
Walter Dr Durckheimer
Reiner Dr Kirrstetter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2079349T3 publication Critical patent/ES2079349T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

SALES CRISTALIZADAS DE CEFEM DE FORMULA GENERAL (IA) (IB) PREPARACIONES FARMACEUTICAS CONTRA INFECCIONES BACTERIANAS QUE CONTIENEN ESTOS DERIVADOS DE CEFEM, PROCEDIMIENTOS PARA LA OBTENCION DE DICHOS DERIVADOS Y PREPARACIONES FARMACEUTICAS, Y SU APLICACION AL COMBATE DE INFECCIONES BACTERIANAS.
ES88102230T 1987-02-25 1988-02-16 Sales por adicion de acidos de cefem cristalizadas y procedimiento para su preparacion. Expired - Lifetime ES2079349T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873706020 DE3706020A1 (de) 1987-02-25 1987-02-25 Kristallisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ES2079349T3 true ES2079349T3 (es) 1996-01-16

Family

ID=6321729

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88102230T Expired - Lifetime ES2079349T3 (es) 1987-02-25 1988-02-16 Sales por adicion de acidos de cefem cristalizadas y procedimiento para su preparacion.

Country Status (27)

Country Link
US (1) US4845087A (es)
EP (1) EP0280157B1 (es)
JP (1) JP2635078B2 (es)
KR (1) KR960003617B1 (es)
AR (1) AR243193A1 (es)
AT (1) ATE128469T1 (es)
AU (1) AU621040B2 (es)
CA (1) CA1297473C (es)
CS (1) CS274422B2 (es)
CY (1) CY2023A (es)
DD (1) DD287505A5 (es)
DE (2) DE3706020A1 (es)
DK (1) DK174331B1 (es)
ES (1) ES2079349T3 (es)
FI (1) FI91530C (es)
GR (1) GR3017917T3 (es)
HU (1) HU200186B (es)
IE (1) IE69040B1 (es)
IL (1) IL85521A0 (es)
MA (1) MA21193A1 (es)
MX (1) MX10537A (es)
NO (1) NO880811L (es)
NZ (1) NZ223594A (es)
PH (1) PH26857A (es)
PT (1) PT86826B (es)
TN (1) TNSN88018A1 (es)
ZA (1) ZA881282B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
US4921851A (en) * 1986-06-09 1990-05-01 Takeda Chemical Industries, Ltd. Cephem compounds, their production and use
IE61679B1 (en) * 1987-08-10 1994-11-16 Fujisawa Pharmaceutical Co Water-soluble antibiotic composition and water-soluble salts of new cephem compounds
EP0366189A3 (en) * 1988-10-24 1992-01-02 Norwich Eaton Pharmaceuticals, Inc. Novel antimicrobial lactam-quinolones
DE4440141A1 (de) * 1994-11-10 1996-05-15 Hoechst Ag Neue kristalline Cephem-Säureadditionssalze und Verfahren zu ihrer Herstellung
KR100389284B1 (ko) * 1999-09-30 2003-06-27 (주)정인종합건축사사무소 경첩
JP5322649B2 (ja) * 2005-10-29 2013-10-23 インターベツト・インターナシヨナル・ベー・ベー セフキノム組成物およびその使用方法
TWI400243B (zh) 2009-07-20 2013-07-01 Intervet Int Bv 製造西喹諾（ｃｅｆｑｕｉｎｏｍｅ）粒子的方法
CN102002058B (zh) * 2010-11-05 2012-04-04 山东鲁抗立科药物化学有限公司 硫酸头孢喹肟的合成方法
WO2012095438A1 (en) 2011-01-12 2012-07-19 Intervet International B.V. Particles and suspensions of cephalosporin antibiotics
CN104031069B (zh) * 2014-05-19 2016-05-18 浙江工业大学 一种硫酸头孢喹肟的制备方法
CN111072686B (zh) * 2019-12-30 2021-02-12 济宁市化工研究院(淮海化工研究院) 一种硫酸头孢喹肟的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE449996B (sv) * 1979-10-02 1987-06-01 Glaxo Group Ltd (6r,7r)-7-/(z)-2-(2-aminotiazol-4-yl)-2-(2-karboxiprop-2-oxiimino)acetamidol/-3-(1-pyridiniummetyl)cef-3-em-4-karboxylat i form av en kristallin bishydroklorid farmaceutisk komposition derav samt anvendning som mellanpr
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3248281A1 (de) * 1982-12-28 1984-06-28 Hoechst Ag, 6230 Frankfurt Kristalisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
DE3316798A1 (de) * 1983-05-07 1984-11-08 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von cephemverbindungen
US4537959A (en) * 1984-03-26 1985-08-27 Eli Lilly And Company Crystalline cephalosporin antibiotic salt
DE3419015A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von cephalosporinen

Also Published As

Publication number Publication date
JPH01216995A (ja) 1989-08-30
NO880811D0 (no) 1988-02-24
IE69040B1 (en) 1996-08-07
PT86826A (pt) 1988-03-01
HU200186B (en) 1990-04-28
HUT46695A (en) 1988-11-28
US4845087A (en) 1989-07-04
TNSN88018A1 (fr) 1990-07-10
CY2023A (en) 1998-02-20
EP0280157A3 (en) 1990-07-18
FI91530B (fi) 1994-03-31
MX10537A (es) 1993-08-01
FI880842A (fi) 1988-08-26
EP0280157B1 (de) 1995-09-27
ATE128469T1 (de) 1995-10-15
CS274422B2 (en) 1991-04-11
AU621040B2 (en) 1992-03-05
CS113688A2 (en) 1990-08-14
EP0280157A2 (de) 1988-08-31
DE3706020A1 (de) 1988-09-08
KR960003617B1 (en) 1996-03-20
DK95788D0 (da) 1988-02-24
PT86826B (pt) 1992-05-29
CA1297473C (en) 1992-03-17
IL85521A0 (en) 1988-08-31
NO880811L (no) 1988-08-26
KR880009973A (ko) 1988-10-06
GR3017917T3 (en) 1996-01-31
ZA881282B (en) 1988-08-23
FI880842A0 (fi) 1988-02-23
PH26857A (en) 1992-11-16
IE880503L (en) 1988-08-25
JP2635078B2 (ja) 1997-07-30
DE3854507D1 (de) 1995-11-02
MA21193A1 (fr) 1988-10-01
NZ223594A (en) 1990-03-27
DK95788A (da) 1988-08-26
DD287505A5 (de) 1991-02-28
FI91530C (fi) 1994-07-11
AR243193A1 (es) 1993-07-30
AU1210688A (en) 1988-09-01
DK174331B1 (da) 2002-12-09

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