ES2075797A1 - Therapeutically active hydroxamic acid derivatives, process for their preparation, pharmaceutical compositions containing them and use of the said compounds in medicine - Google Patents
Therapeutically active hydroxamic acid derivatives, process for their preparation, pharmaceutical compositions containing them and use of the said compounds in medicineInfo
- Publication number
- ES2075797A1 ES2075797A1 ES09301818A ES9301818A ES2075797A1 ES 2075797 A1 ES2075797 A1 ES 2075797A1 ES 09301818 A ES09301818 A ES 09301818A ES 9301818 A ES9301818 A ES 9301818A ES 2075797 A1 ES2075797 A1 ES 2075797A1
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- medicine
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
Therapeutically active hydroxamic acid derivatives, processes for their preparation, pharmaceutical compositions containing them and use of the said compounds in medicine. This invention relates to therapeutically active hydroxamic acid derivatives, processes for their preparation, pharmaceutical compositions containing them and use of the said compounds in medicine, specifically compounds of formula (I) in which: R2 is an R6-A- group where A is a saturated or unsaturated, straight or branched divalent hydrocarbon chain, R3 is an R7-(Bn)- group where n is 0 or 1, B is a saturated or unsaturated, straight or branched divalent hydrocarbon chain, R4 is hydrogen or methyl, R5 is hydrogen, or an alkyl or amino group or R3 and R5 taken together are a divalent hydrocarbon chain. These compounds inhibit the action of metal proteinases and are useful for the treatment or prophylaxis of conditions which give rise to tissue disintegration.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9301818A ES2075797B1 (en) | 1993-08-18 | 1993-08-18 | DERIVATIVES OF THERAPEUTICALLY ACTIVE HYDROXAMIC ACIDS, PROCEDURE FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND THE USE OF SUCH COMPOUNDS IN MEDICINE. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9301818A ES2075797B1 (en) | 1993-08-18 | 1993-08-18 | DERIVATIVES OF THERAPEUTICALLY ACTIVE HYDROXAMIC ACIDS, PROCEDURE FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND THE USE OF SUCH COMPOUNDS IN MEDICINE. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2075797A1 true ES2075797A1 (en) | 1995-10-01 |
ES2075797B1 ES2075797B1 (en) | 1996-05-16 |
Family
ID=8282876
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9301818A Expired - Fee Related ES2075797B1 (en) | 1993-08-18 | 1993-08-18 | DERIVATIVES OF THERAPEUTICALLY ACTIVE HYDROXAMIC ACIDS, PROCEDURE FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND THE USE OF SUCH COMPOUNDS IN MEDICINE. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2075797B1 (en) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991002716A2 (en) * | 1989-08-24 | 1991-03-07 | British Bio-Technology Limited | Hydroxamic acid based collagenase inhibitors |
WO1994002447A1 (en) * | 1992-07-23 | 1994-02-03 | British Biotech Pharmaceuticals Limited | Hydroxamic acid derivatives as metalloproteinase inhibitors |
-
1993
- 1993-08-18 ES ES9301818A patent/ES2075797B1/en not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991002716A2 (en) * | 1989-08-24 | 1991-03-07 | British Bio-Technology Limited | Hydroxamic acid based collagenase inhibitors |
WO1994002447A1 (en) * | 1992-07-23 | 1994-02-03 | British Biotech Pharmaceuticals Limited | Hydroxamic acid derivatives as metalloproteinase inhibitors |
Also Published As
Publication number | Publication date |
---|---|
ES2075797B1 (en) | 1996-05-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC2A | Transfer of patent |
Owner name: BRITISH BIOTECH PHARMACEUTICALS LIMITED |
|
FD1A | Patent lapsed |
Effective date: 20100528 |