ES2075709T3 - Derivados amidicos del antibiotico a 40926. - Google Patents

Derivados amidicos del antibiotico a 40926.

Info

Publication number
ES2075709T3
ES2075709T3 ES92915890T ES92915890T ES2075709T3 ES 2075709 T3 ES2075709 T3 ES 2075709T3 ES 92915890 T ES92915890 T ES 92915890T ES 92915890 T ES92915890 T ES 92915890T ES 2075709 T3 ES2075709 T3 ES 2075709T3
Authority
ES
Spain
Prior art keywords
antibiotic
alkylaminocarbonyl
substituent
amidic derivatives
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92915890T
Other languages
English (en)
Inventor
Adriano Malabarba
Romeo Ciabatti
Gianbattista Panzone
Alessandra Maria Marazzi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Gruppo Lepetit SpA
Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26128958&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2075709(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gruppo Lepetit SpA, Lepetit SpA filed Critical Gruppo Lepetit SpA
Application granted granted Critical
Publication of ES2075709T3 publication Critical patent/ES2075709T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

LA INVENCION SE DIRIGE A NUEVOS DERIVADOS DEL ANTIBIOTICO A 40926 QUE SE CARACTERIZAN POR TENER UN SUSTITUYENTE DE CARBOXIDO, ALCOXICARBONILO C1-C4, AMINOCARBONILO, ALQUILAMINOCARBONIL C1-C4, DIALQUILAMINOCARBONIL C1-C4 O HIDROXIMETILO SOBRE LA MOLECULA DE NACILAMINOGLUCURONIL Y UN SUSTITUYENTE DE HIDROXIDO O DE POLIAMINO EN LA POSICION 63 DE LA MOLECULA. LOS COMPUESTOS DE LA INVENCION MUESTRAN UNA ALTA ACTIVIDAD IN VITRO CONTRA LOS "ENTEROCOCCI" Y LOS "STAPHILOCOCCI" RESISTENTES A LOS GLICOPEPTIDOS.
ES92915890T 1991-07-29 1992-07-14 Derivados amidicos del antibiotico a 40926. Expired - Lifetime ES2075709T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP91112685 1991-07-29
EP92109906 1992-06-12

Publications (1)

Publication Number Publication Date
ES2075709T3 true ES2075709T3 (es) 1995-10-01

Family

ID=26128958

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92915890T Expired - Lifetime ES2075709T3 (es) 1991-07-29 1992-07-14 Derivados amidicos del antibiotico a 40926.

Country Status (24)

Country Link
EP (2) EP0596929B1 (es)
JP (1) JP3418762B2 (es)
KR (1) KR100242682B1 (es)
AT (1) ATE125551T1 (es)
AU (1) AU666862B2 (es)
BG (1) BG61124B2 (es)
CA (1) CA2109601C (es)
CZ (1) CZ285703B6 (es)
DE (1) DE69203724T2 (es)
DK (1) DK0596929T3 (es)
ES (1) ES2075709T3 (es)
FI (1) FI112662B (es)
GR (1) GR3017897T3 (es)
HU (2) HU223946B1 (es)
IE (1) IE68420B1 (es)
IL (1) IL102623A (es)
MX (1) MX9204394A (es)
NO (1) NO314150B1 (es)
NZ (1) NZ243735A (es)
PL (1) PL171813B1 (es)
RU (1) RU2125058C1 (es)
TW (1) TW218021B (es)
UA (1) UA41283C2 (es)
WO (1) WO1993003060A1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5606036A (en) * 1991-03-27 1997-02-25 Gruppo Lepetit Spa Antibiotic A 40926 ester derivatives
US5840684A (en) * 1994-01-28 1998-11-24 Eli Lilly And Company Glycopeptide antibiotic derivatives
MY128335A (en) * 1994-01-28 2007-01-31 Lilly Co Eli Glycopeptide antibiotic derivatives
PT836619E (pt) * 1995-07-05 2004-11-30 Aventis Bulk S P A Purificacao de antibioticos dalba-heptidicos por focagem isoelectrica
CA2250578C (en) 1996-04-23 2003-06-24 Versicor Inc. Improved chemical process for preparing amide derivatives of antibiotic a 40926
US6004959A (en) * 1996-05-30 1999-12-21 Hoechst Marion Roussel, Inc. Alkyloxyamino substituted fluorenones and their use as protein kinase-C inhibitors
SG87877A1 (en) * 1998-12-23 2002-04-16 Advanced Medicine Inc Glycopeptide derivatives and pharmaceutical compositions containing the same
CN1249081C (zh) * 1998-12-23 2006-04-05 施万制药 糖肽衍生物或含有它们的药物组合物
TWI312785B (en) 2001-08-24 2009-08-01 Theravance Inc Process for preparing vancomycin derivatives
TWI275594B (en) 2001-08-24 2007-03-11 Theravance Inc Process for preparing vancomycin phosphonate derivatives
KR100478533B1 (ko) * 2002-07-30 2005-03-28 한국수력원자력 주식회사 레이저를 이용한 탈륨 동위원소 분리방법
US20060074014A1 (en) 2002-11-18 2006-04-06 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
US7119061B2 (en) 2002-11-18 2006-10-10 Vicuron Pharmaceuticals, Inc. Dalbavancin compositions for treatment of bacterial infections
DK1565201T3 (en) 2002-11-18 2019-02-25 Vicuron Pharmaceuticals Llc METHODS OF ADMINISTRATING DALBAVANCIN TO TREAT Bacterial Infections
WO2004110473A1 (en) 2003-05-27 2004-12-23 Theravance, Inc. Use of a polyene macrolide antifungal agent in combination with a glycopeptide antibacterial agent
DE602004010915T2 (de) 2003-07-22 2008-12-11 Theravance, Inc., South San Francisco Verwendung eines antimykotischen echinocandin-mittels in kombination mit einem antibakteriellen glycopeptid-mittel
KR20070092719A (ko) 2004-11-29 2007-09-13 고쿠리츠 다이가쿠 호우징 나고야 다이가쿠 글리코펩타이드 항생 물질 모노머 유도체
TW200808818A (en) 2006-05-26 2008-02-16 Shionogi & Co Glycopeptide antibiotic derivatives
WO2009081958A1 (ja) 2007-12-26 2009-07-02 Shionogi & Co., Ltd. グリコペプチド抗生物質配糖化誘導体
KR20230130679A (ko) * 2021-01-11 2023-09-12 셀리아 파마슈티칼즈 에이피에스 합성 방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8608809D0 (en) * 1986-04-11 1986-05-14 Lepetit Spa Antibiotic
GB8726859D0 (en) * 1987-11-17 1987-12-23 Lepetit Spa 22-dechlorotei-coplanins
ES2083374T3 (es) * 1988-12-27 1996-04-16 Lepetit Spa Derivados amidicos en posicion c63 de 34-des(acetilglucosaminil)-34-desoxi-teicoplaninas.
GB2231846B (en) * 1989-05-25 1993-02-24 Hadlum Brothers Ltd A hand held carrier
WO1992010516A1 (en) * 1990-12-05 1992-06-25 Gruppo Lepetit S.P.A. 38-decarboxy-38-hydroxymethyl derivatives of teicoplanin antibiotics, and a process for preparing them
CA2099866C (en) * 1991-03-27 2002-07-09 Rolf H. Hermann Antibiotic a 40926 ester derivatives

Also Published As

Publication number Publication date
JP3418762B2 (ja) 2003-06-23
PL171813B1 (pl) 1997-06-30
NO314150B1 (no) 2003-02-03
UA41283C2 (uk) 2001-09-17
DE69203724T2 (de) 1996-01-18
HU9400256D0 (en) 1994-05-30
MX9204394A (es) 1993-01-29
IE922451A1 (en) 1993-02-10
FI940394A0 (fi) 1994-01-26
EP0596929A1 (en) 1994-05-18
IL102623A (en) 1996-10-16
NO934722L (no) 1994-02-14
EP0525499A1 (en) 1993-02-03
KR100242682B1 (ko) 2000-02-01
IL102623A0 (en) 1993-01-14
TW218021B (es) 1993-12-21
WO1993003060A1 (en) 1993-02-18
FI112662B (fi) 2003-12-31
HU211347A9 (en) 1995-11-28
CA2109601C (en) 2002-07-02
DK0596929T3 (da) 1995-09-11
GR3017897T3 (en) 1996-01-31
DE69203724D1 (de) 1995-08-31
NO934722D0 (no) 1993-12-20
FI940394A (fi) 1994-01-26
BG61124B2 (bg) 1996-11-29
JPH06509347A (ja) 1994-10-20
CZ285703B6 (cs) 1999-10-13
CZ19294A3 (en) 1994-11-16
RU2125058C1 (ru) 1999-01-20
CA2109601A1 (en) 1993-02-18
NZ243735A (en) 1995-01-27
ATE125551T1 (de) 1995-08-15
AU2326292A (en) 1993-03-02
IE68420B1 (en) 1996-06-12
EP0596929B1 (en) 1995-07-26
HUT66080A (en) 1994-09-28
AU666862B2 (en) 1996-02-29
HU223946B1 (hu) 2005-03-29

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