ES2071793T3 - Nuevos derivados de la pirrolidona, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. - Google Patents

Nuevos derivados de la pirrolidona, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.

Info

Publication number
ES2071793T3
ES2071793T3 ES90401387T ES90401387T ES2071793T3 ES 2071793 T3 ES2071793 T3 ES 2071793T3 ES 90401387 T ES90401387 T ES 90401387T ES 90401387 T ES90401387 T ES 90401387T ES 2071793 T3 ES2071793 T3 ES 2071793T3
Authority
ES
Spain
Prior art keywords
pyrrolidone
contain
pharmaceutical compositions
preparation procedure
new derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90401387T
Other languages
English (en)
Inventor
Gilbert Regnier
Alain Dhainaut
Jean Lepagnol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Application granted granted Critical
Publication of ES2071793T3 publication Critical patent/ES2071793T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C07D207/48—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

NUEVOS DERIVADOS DE LA PIRROLIDONA UTILIZABLES COMO MEDICAMENTOS, Y QUE RESPONDEN A LA FORMULA: (FIG. A), EN LA QUE R ES UN GRUPO OR", SR" O R3R4N-, SIENDO R", R3 Y R4 TALES COMO SE DEFINE EN LA DESCRIPCION; R'' ES UN GRUPO ALQUILO O ARILO, CADA UNO EVENTUALMENTE SUSTITUIDO; Y EL CARBONO EN POSICION 5 DEL CICLO PIRROLIDONA, SUSTITUIDO POR CH2R, TIENE LA CONFIGURACION R O S. ESTOS NUEVOS DERIVADOS Y SUS SALES FISIOLOGICAMENTE COMPATIBLES SE PUEDEN USAR EN TERAPIA, ESPECIALMENTE EN EL TRATAMIENTO DE ASTENIAS, SINDROMAS ISQUEMICOS Y ENFERMEDADES NERVIOSAS LIGADAS AL ENVEJECIMIENTO NORMAL O PATOLOGICO.
ES90401387T 1989-05-31 1990-05-23 Nuevos derivados de la pirrolidona, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. Expired - Lifetime ES2071793T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8907153A FR2647785B1 (fr) 1989-05-31 1989-05-31 Nouveaux derives de la pyrrolidone, leur procede de preparation et les compositions pharmaceutiques les renfermant

Publications (1)

Publication Number Publication Date
ES2071793T3 true ES2071793T3 (es) 1995-07-01

Family

ID=9382204

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90401387T Expired - Lifetime ES2071793T3 (es) 1989-05-31 1990-05-23 Nuevos derivados de la pirrolidona, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.

Country Status (15)

Country Link
US (1) US5066651A (es)
EP (1) EP0401093B1 (es)
JP (1) JPH0688972B2 (es)
AT (1) ATE119149T1 (es)
AU (1) AU617945B2 (es)
CA (1) CA2017044A1 (es)
DE (1) DE69017265T2 (es)
DK (1) DK0401093T3 (es)
ES (1) ES2071793T3 (es)
FR (1) FR2647785B1 (es)
IE (1) IE67060B1 (es)
NZ (1) NZ233618A (es)
OA (1) OA09451A (es)
PT (1) PT94196B (es)
ZA (1) ZA903944B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1770788A3 (en) 2005-09-29 2011-09-21 Semiconductor Energy Laboratory Co., Ltd. Semiconductor device having oxide semiconductor layer and manufacturing method thereof
TWI613489B (zh) 2008-12-03 2018-02-01 半導體能源研究所股份有限公司 液晶顯示裝置
CN102349158B (zh) 2009-03-12 2015-05-06 株式会社半导体能源研究所 制造半导体器件的方法
TWI556323B (zh) 2009-03-13 2016-11-01 半導體能源研究所股份有限公司 半導體裝置及該半導體裝置的製造方法
CN112437768A (zh) * 2018-05-11 2021-03-02 英联邦高等教育***坦普尔大学 作为5-羟色胺受体7调节剂的新型官能化内酰胺及其使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2553409B1 (fr) * 1983-10-18 1986-04-18 Choay Sa Nouveaux benzenesulfonyl-lactames, leur procede de preparation et leur application comme substance active de compositions pharmaceutiques
DK167393B1 (da) * 1985-12-30 1993-10-25 Roussel Uclaf 1-sulfonyl-2-oxo-pyrrolidinderivater, deres fremstilling og farmaceutiske praeparater med indhold deraf
WO1989009767A1 (en) * 1988-04-15 1989-10-19 Taiho Pharmaceutical Company, Limited Carbamoyl-2-pyrrolidinone compounds

Also Published As

Publication number Publication date
EP0401093A1 (fr) 1990-12-05
PT94196B (pt) 1996-12-31
OA09451A (fr) 1992-10-15
FR2647785B1 (fr) 1991-09-06
CA2017044A1 (fr) 1990-11-30
ZA903944B (en) 1991-03-27
ATE119149T1 (de) 1995-03-15
JPH0320259A (ja) 1991-01-29
PT94196A (pt) 1991-02-08
JPH0688972B2 (ja) 1994-11-09
US5066651A (en) 1991-11-19
EP0401093B1 (fr) 1995-03-01
FR2647785A1 (fr) 1990-12-07
DK0401093T3 (da) 1995-07-10
NZ233618A (en) 1991-11-26
DE69017265D1 (de) 1995-04-06
IE901934L (en) 1990-11-30
IE67060B1 (en) 1996-02-21
AU617945B2 (en) 1991-12-05
AU5608790A (en) 1990-12-06
DE69017265T2 (de) 1995-10-19

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