ES2066120T3 - Uso de derivados de bencimidazol como agentes antibacterianos. - Google Patents

Uso de derivados de bencimidazol como agentes antibacterianos.

Info

Publication number
ES2066120T3
ES2066120T3 ES90301256T ES90301256T ES2066120T3 ES 2066120 T3 ES2066120 T3 ES 2066120T3 ES 90301256 T ES90301256 T ES 90301256T ES 90301256 T ES90301256 T ES 90301256T ES 2066120 T3 ES2066120 T3 ES 2066120T3
Authority
ES
Spain
Prior art keywords
antibacterial agents
stands
hydrogen
bencimidazole
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90301256T
Other languages
English (en)
Inventor
Tomoyuki Iwahi
Hiroshi Satoh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26370930&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2066120(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ES2066120T3 publication Critical patent/ES2066120T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof

Abstract

EL COMPUESTO REPRESENTADO POR LA FORMULA: [EN DONDE R1 REPRESENTA HIDROGENO, METOXILO O TRIFLUOROMETILO; SIENDO R2 Y R3, IDENTICOS O DIFERENTE UNO DEL OTRO, HIDROGENO O METILO; R4 REPRESENTA UN HIDROCARBURO RESIDUAL OPCIONALMENTE SUBSTITUIDO; Y N DENOTA 0 O 1] O UNA SAL DE EL, MUESTRA EXCELENTE ACTIVIDAD ANTIBACTERIANA, CONTRA EL GENERO "CAMPYLOBACTER", ESPECIALMENTE CONTRA "CAMPYLOBACTER PYLORI", Y SE EMPLEAN PARA PREVENIR O TRATAR ENFERMEDADES INFECCIOSAS OCASIONADAS POR DICHA BACTERIA.
ES90301256T 1989-02-10 1990-02-06 Uso de derivados de bencimidazol como agentes antibacterianos. Expired - Lifetime ES2066120T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP3237489 1989-02-10
JP23923389 1989-09-15

Publications (1)

Publication Number Publication Date
ES2066120T3 true ES2066120T3 (es) 1995-03-01

Family

ID=26370930

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90301256T Expired - Lifetime ES2066120T3 (es) 1989-02-10 1990-02-06 Uso de derivados de bencimidazol como agentes antibacterianos.

Country Status (10)

Country Link
US (1) US5013743A (es)
EP (1) EP0382489B1 (es)
AT (1) ATE114114T1 (es)
CA (1) CA2009741C (es)
DE (1) DE69014141T2 (es)
DK (1) DK0382489T3 (es)
ES (1) ES2066120T3 (es)
FI (2) FI100168B (es)
GR (1) GR3014973T3 (es)
NO (1) NO900639L (es)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5338723A (en) * 1989-10-13 1994-08-16 Merck & Co., Inc. Fibrinogen receptor antagonists
ES2169022T3 (es) * 1990-09-14 2002-07-01 Byk Gulden Lomberg Chem Fab Utilizacion de derivados de (piridil-metil-sulfinil)-1-h-bencimidazol para el tratamiento de enfermedades provocadas por helicobacter.
TW209174B (es) * 1991-04-19 1993-07-11 Takeda Pharm Industry Co Ltd
IL105155A (en) * 1992-04-24 1999-05-09 Astra Ab Synergistic combination of an inhibitor of gastric acid secretion with an acid-breaking antibiotic
US5504082A (en) * 1992-06-01 1996-04-02 Yoshitomi Pharmaceutical Industries, Ltd. Pyridine compound and pharmaceutical compostions
KR0144793B1 (ko) * 1992-07-08 1998-07-15 제임스 클리프튼 보올딩 돼지에서 위궤양을 완화시키기 위한 벤즈이미다졸
AU674015B2 (en) * 1992-07-28 1996-12-05 Astra Aktiebolag Injection and injection kit containing omeprazole and its analogs
ATE137969T1 (de) * 1992-08-21 1996-06-15 Eisai Co Ltd Benzimidazolverbindungen als antibiotika gegen campylobacter pylon
WO1994013290A1 (de) * 1992-12-10 1994-06-23 Byk Gulden Lomberg Chemische Fabrik Gmbh Verwendung von alkylthiopyridinen zur bekämpfung von heliobacter-bakterien
JPH06298611A (ja) * 1993-04-16 1994-10-25 Nippon Chemiphar Co Ltd 抗菌剤
JPH08512037A (ja) * 1993-06-29 1996-12-17 ビイク グルデン ロンベルク ヒェーミッシェ ファブリーク ゲゼルシャフト ミット ベシュレンクテル ハフツング 置換されたアリールチオアルキルチオピリジン
US6489346B1 (en) * 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6699885B2 (en) * 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US8071128B2 (en) * 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
ATE271555T1 (de) 1998-01-14 2004-08-15 Uab Research Foundation Verfahren zur herstellung und screening von inhibitoren des bakteriellen nad synthetase enzyms, verbindungen daraus und methoden zur behandlung bakterieller und mikrobieller infektionen mit diesen inhibitoren
US6861448B2 (en) * 1998-01-14 2005-03-01 Virtual Drug Development, Inc. NAD synthetase inhibitors and uses thereof
FI104384B (fi) 1998-06-05 2000-01-14 Valmet Corp Laitteisto ja menetelmä viiraveden ja tuoremassan sekoittamiseksi viirakaivon jälkeisessä kanavassa
EP1310252A4 (en) * 2000-08-18 2009-06-10 Takeda Pharmaceutical INJECTIONS
AU2002332178B2 (en) * 2001-09-18 2005-12-08 Zeria Pharmaceutical Co., Ltd. Benzimidazole derivatives
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
MXPA04007169A (es) * 2002-01-25 2004-10-29 Santarus Inc Suministro transmucosal de inhibidores de bomba de protones.
US8367111B2 (en) * 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US20050220870A1 (en) * 2003-02-20 2005-10-06 Bonnie Hepburn Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid
US20040248942A1 (en) * 2003-02-20 2004-12-09 Bonnie Hepburn Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid
US20050031700A1 (en) * 2003-07-18 2005-02-10 Sanatarus, Inc. Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20050037070A1 (en) * 2003-07-18 2005-02-17 Santarus, Inc. Pharmaceutical formulatins useful for inhibiting acid secretion and methods for making and using them
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
JP2007522217A (ja) * 2004-02-10 2007-08-09 サンタラス インコーポレイティッド プロトンポンプ阻害剤、緩衝剤および非ステロイド系抗炎症薬の組み合わせ
AU2005249367A1 (en) * 2004-04-16 2005-12-15 Santarus, Inc. Combination of proton pump inhibitor, buffering agent, and prokinetic agent
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20060024362A1 (en) * 2004-07-29 2006-02-02 Pawan Seth Composition comprising a benzimidazole and process for its manufacture
US8747895B2 (en) * 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) * 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
MX2007004741A (es) 2004-10-21 2007-09-07 Eurand Pharmaceuticals Ltd Composiciones farmaceuticas con sabor enmascarado con formadores de poro gastrosolubles.
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
JP2009511481A (ja) * 2005-10-06 2009-03-19 オースペックス・ファーマシューティカルズ・インコーポレイテッド 増強された治療特性を持つ、胃Ｈ＋，Ｋ＋−ＡＴＰａｓｅの重水素化阻害剤
ATE533757T1 (de) * 2006-03-10 2011-12-15 Arigen Pharmaceuticals Inc Neues pyridinderivat mit wirkung gegen helicobacter pylori
JP2009538901A (ja) * 2006-06-01 2009-11-12 デクセル ファーマ テクノロジーズ エルティーディー． 複式ユニット製薬的製剤
EP2023721A2 (en) * 2006-06-05 2009-02-18 Auspex Pharmaceuticals Inc. Preparation and utility of substituted erythromycin analogs
GB2444593B (en) 2006-10-05 2010-06-09 Santarus Inc Novel formulations for immediate release of proton pump inhibitors and methods of using these formulations
US20090092658A1 (en) * 2007-10-05 2009-04-09 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations
CA2667682A1 (en) 2006-10-27 2008-05-15 The Curators Of The University Of Missouri Compositions comprising acid labile proton pump inhibiting agents, at least one other pharmaceutically active agent and methods of using same
EP2420500A4 (en) * 2009-04-09 2012-09-05 Arigen Pharmaceuticals Inc PYRIDINTHIODERIVATE AND PHARMACEUTICAL COMPOSITION THEREOF AND WITH ANTI-HELIDOBACTER PYLORI EFFECT
CA2782285A1 (en) 2009-12-02 2011-06-09 Luigi Mapelli Fexofenadine microcapsules and compositions containing them
UY33173A (es) * 2010-01-08 2011-07-29 Eurand Inc
US20170042806A1 (en) 2015-04-29 2017-02-16 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
WO2024075017A1 (en) 2022-10-04 2024-04-11 Zabirnyk Arsenii Inhibition of aortic valve calcification

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
JPS62277322A (ja) * 1986-02-13 1987-12-02 Takeda Chem Ind Ltd 安定化された腸溶性抗潰瘍固形組成物
JP2694361B2 (ja) * 1989-02-09 1997-12-24 アストラ アクチエボラグ 抗菌剤

Also Published As

Publication number Publication date
NO900639L (no) 1990-08-13
ATE114114T1 (de) 1994-12-15
FI900662A0 (fi) 1990-02-09
DE69014141T2 (de) 1995-05-24
EP0382489B1 (en) 1994-11-17
GR3014973T3 (en) 1995-05-31
CA2009741C (en) 1999-03-23
US5013743A (en) 1991-05-07
FI104045B1 (fi) 1999-11-15
FI940951A (fi) 1994-02-28
DK0382489T3 (da) 1995-01-16
FI104045B (fi) 1999-11-15
EP0382489A3 (en) 1991-06-12
FI940951A0 (fi) 1994-02-28
FI100168B (fi) 1997-10-15
NO900639D0 (no) 1990-02-09
CA2009741A1 (en) 1990-08-10
EP0382489A2 (en) 1990-08-16
DE69014141D1 (de) 1994-12-22

Similar Documents

Publication Publication Date Title
ES2066120T3 (es) Uso de derivados de bencimidazol como agentes antibacterianos.
ES2144421T3 (es) Nuevo derivado tetrapeptidico.
DE60204452D1 (de) Pyrazolo[1,5]pyridinderivate
PT705833E (pt) Derivado de dc-89
YU11997A (sh) Laktamski derivati i njihove farmaceutske kompozicije
NO900306D0 (no) Fremgangsmaate for fremstilling av nye pyrazolopyridin-forbindelser.
ES2141559T3 (es) Derivados de 2-ciano-1-sulfonamidofenil-1,3-diona y su uso como herbicidas.
PT718293E (pt) Composto ciclodepsipeptidico
ES2115600T3 (es) Derivados de 1-metilcarbapenem y procedimiento para su preparacion.
FI940229A (fi) Trisykliset kondensoituneet heterosykliset yhdisteet, niiden valmistus ja käyttö
NZ217650A (en) Quinoline derivatives and pharmaceutical compositions
FI935800A0 (fi) Antidepressiva och mot Parkisons sjukdom verksamma foereningar
ATE143023T1 (de) Chirale 1,5-diiodo-2-methoxy oder benzyloxy zwischenprodukte
ES2178765T3 (es) Nuevos derivados de 1,7,7-trimetil-biciclo (2.2.1) heptano.
FI952420A0 (fi) Glukopyranosidibentsotiofeenit
FI941963A (fi) Pyridiinijohdannaiset, niiden valmistus ja käyttö
DE69017627D1 (de) Isochinolinderivate und ihre Salze als Proteasehemmer.
DE69711506D1 (de) Methylsulfomycin 1, Verfahren zu dessen Herstellung und Verwendung
FI921475A0 (fi) 1,4-dihydro-4-oxo-3-kinolinderivat som selektivt toxiska antibakteriella aemenn hos daeggdjur.
ES2090056T3 (es) Derivados de pirroloquinolina, su utilizacion como agentes antimicrobianos y procedimientos para su preparacion.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 382489

Country of ref document: ES