ES2065842A1 - Application of manoyl ent-3[beta],6[beta] ,12[beta]-trihydroxy-13-epi-oxide as adenylatocyclase activator - Google Patents

Application of manoyl ent-3[beta],6[beta] ,12[beta]-trihydroxy-13-epi-oxide as adenylatocyclase activator

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Publication number
ES2065842A1
ES2065842A1 ES09300489A ES9300489A ES2065842A1 ES 2065842 A1 ES2065842 A1 ES 2065842A1 ES 09300489 A ES09300489 A ES 09300489A ES 9300489 A ES9300489 A ES 9300489A ES 2065842 A1 ES2065842 A1 ES 2065842A1
Authority
ES
Spain
Prior art keywords
beta
manoyl
ent
oxide
trihydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09300489A
Other languages
Spanish (es)
Other versions
ES2065842B1 (en
Inventor
Lopez De Hierr Garcia-Granados
Rodriguez Antonio Martinez
Sanchez Francisco Rivas
Mirta Flavia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad de Granada
Original Assignee
Universidad de Granada
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad de Granada filed Critical Universidad de Granada
Priority to ES9300489A priority Critical patent/ES2065842B1/en
Publication of ES2065842A1 publication Critical patent/ES2065842A1/en
Application granted granted Critical
Publication of ES2065842B1 publication Critical patent/ES2065842B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

Application of manoyl ent-3[beta],6[beta],12[beta]- trihydroxy-13-epi-oxide as adenylatocyclase activator. A product to potentiate the activity of adenylatocyclase is patented. It is a manoyl enantio-13-epi-oxide, the name of which is manoyl ent-3[beta],6[beta],12[beta]- trihydroxy-13-epi-oxide (product 3 of the report, which can also be called manoyl ent-3[beta],6[beta],12[beta]- trihydroxy-13(S)-oxide or ent-[8[alpha],13(S)]-epoxy- 3[beta],6[beta],12[beta]-trihydroxylabd-14-ene).
ES9300489A 1993-03-10 1993-03-10 APPLICATION OF ENT-3B, 6B, 12B-TRIHIDROXI-13-EPI-MANOYL OXIDE AS AN ADENYLATOCICLASE ACTIVATOR Expired - Fee Related ES2065842B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9300489A ES2065842B1 (en) 1993-03-10 1993-03-10 APPLICATION OF ENT-3B, 6B, 12B-TRIHIDROXI-13-EPI-MANOYL OXIDE AS AN ADENYLATOCICLASE ACTIVATOR

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9300489A ES2065842B1 (en) 1993-03-10 1993-03-10 APPLICATION OF ENT-3B, 6B, 12B-TRIHIDROXI-13-EPI-MANOYL OXIDE AS AN ADENYLATOCICLASE ACTIVATOR

Publications (2)

Publication Number Publication Date
ES2065842A1 true ES2065842A1 (en) 1995-02-16
ES2065842B1 ES2065842B1 (en) 1996-02-16

Family

ID=8281060

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9300489A Expired - Fee Related ES2065842B1 (en) 1993-03-10 1993-03-10 APPLICATION OF ENT-3B, 6B, 12B-TRIHIDROXI-13-EPI-MANOYL OXIDE AS AN ADENYLATOCICLASE ACTIVATOR

Country Status (1)

Country Link
ES (1) ES2065842B1 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0126313A2 (en) * 1983-04-26 1984-11-28 BEHRINGWERKE Aktiengesellschaft Use of diterpene derivatives of forskolin for immune stimulation
EP0222413A2 (en) * 1985-11-15 1987-05-20 Nippon Kayaku Kabushiki Kaisha Novel forskolin derivatives
EP0294695A2 (en) * 1987-06-06 1988-12-14 Hoechst Aktiengesellschaft New polyoxygenated labdane derivatives, a process for their preparation, and their use as medicaments
EP0447962A1 (en) * 1990-03-17 1991-09-25 Hoechst Aktiengesellschaft Labdanes and process for their preparation

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0126313A2 (en) * 1983-04-26 1984-11-28 BEHRINGWERKE Aktiengesellschaft Use of diterpene derivatives of forskolin for immune stimulation
EP0222413A2 (en) * 1985-11-15 1987-05-20 Nippon Kayaku Kabushiki Kaisha Novel forskolin derivatives
EP0294695A2 (en) * 1987-06-06 1988-12-14 Hoechst Aktiengesellschaft New polyoxygenated labdane derivatives, a process for their preparation, and their use as medicaments
EP0447962A1 (en) * 1990-03-17 1991-09-25 Hoechst Aktiengesellschaft Labdanes and process for their preparation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF MEDICINAL CHEMISTRY, Vol. 26, pßg. 436-439, 1983; K.B. SEAMON et al.: "Structure-Activity Relationships for activation of Adenylate Cyclase by the diterpene Forskolin and its derivatives". *

Also Published As

Publication number Publication date
ES2065842B1 (en) 1996-02-16

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