ES2063132T3 - Articulo para realizar ensayos inmunologicos usando tinciones organicas y procedimientos para producirlo y utilizarlo. - Google Patents
Articulo para realizar ensayos inmunologicos usando tinciones organicas y procedimientos para producirlo y utilizarlo.Info
- Publication number
- ES2063132T3 ES2063132T3 ES89306717T ES89306717T ES2063132T3 ES 2063132 T3 ES2063132 T3 ES 2063132T3 ES 89306717 T ES89306717 T ES 89306717T ES 89306717 T ES89306717 T ES 89306717T ES 2063132 T3 ES2063132 T3 ES 2063132T3
- Authority
- ES
- Spain
- Prior art keywords
- article
- bound
- immunologically reactive
- reactive component
- procedures
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
- G01N33/552—Glass or silica
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
- G01N33/545—Synthetic resin
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
UN SOPORTE EN FASE SOLIDA ADECUADA PARA ENSAYOS INMUNOLOGICOS SE MANCHA CON UN COLORANTE ORGANICO QUE TIENE UNA CARGA POSITIVA NETA Y UNA ESTRUCTURA DE ANILLO AROMATICO HIDROFOBO. UN COMPONENTE INMUNOLOGICAMENTE REACTIVO, QUE TIENE UNA CARGA NEGATIVA NETA, SE INMOVILIZA POR EL COLORANTE EN EL SOPORTE MEDIANTE REACCIONES NO COVALENTES. EL COMPONENTE INMUNOLOGICAMENTE REACTIVO ESTA FUERTEMENTE UNIDO AL COLORANTE ORGANICO. ESTO ES UNA VENTAJA CUANDO SE EFECTUAN ENSAYOS INMUNOLOGICOS QUE UTILIZAN INSTRUMENTOS DE LAVADO AUTOMATICOS. SE AÑADE UNA MUESTRA DE UN FLUIDO BIOLOGICO AL OBJETO QUE TIENE EL COMPONENTE INMUNOLOGICAMENTE REACTIVO UNIDO A EL, PARA DETECTAR LA PRESENCIA DE ANTIGENOS O ANTICUERPOS EN EL FLUIDO BIOLOGICO ESPECIFICO PARA EL COMPONENTE INMUNOLOGICO UNIDO. LA PRESENCIA DEL COMPLEJO ANTIGENO-ANTICUERPO SE PUEDE DETERMINAR POR CUALQUIER METODO CONOCIDO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/215,041 US4963478A (en) | 1988-07-05 | 1988-07-05 | Article for preforming immunological assays utilizing organic dyes and method for producing and utilizing same |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2063132T3 true ES2063132T3 (es) | 1995-01-01 |
Family
ID=22801392
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES89306717T Expired - Lifetime ES2063132T3 (es) | 1988-07-05 | 1989-07-03 | Articulo para realizar ensayos inmunologicos usando tinciones organicas y procedimientos para producirlo y utilizarlo. |
Country Status (9)
Country | Link |
---|---|
US (2) | US4963478A (es) |
EP (1) | EP0350233B1 (es) |
JP (1) | JP2732124B2 (es) |
AT (1) | ATE112631T1 (es) |
AU (1) | AU619019B2 (es) |
CA (1) | CA1340575C (es) |
DE (1) | DE68918643T2 (es) |
ES (1) | ES2063132T3 (es) |
NZ (1) | NZ229765A (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5759774A (en) * | 1988-05-18 | 1998-06-02 | Cobe Laboratories, Inc. | Method of detecting circulating antibody types using dried or lyophilized cells |
US5192663A (en) * | 1988-11-04 | 1993-03-09 | Immucor, Inc. | Article having an organic dye and a monolayer of dried mammalian cells and a method for utilizing the article |
FR2679659B1 (fr) * | 1991-07-23 | 1993-11-19 | Medgenix Diagnostic Sa | Procede de dosage in vitro de molecules au niveau de leur site de production par des cellules en culture et format technologique adapte. |
DE4322884A1 (de) * | 1992-10-09 | 1994-04-14 | Bayer Ag | Biologisch aktive Polymere |
FR2760093B1 (fr) * | 1997-02-21 | 1999-05-14 | Univ Henri Poincare Nancy I | Procede et trousse pour detecter la presence d'une immunoglobuline |
AU7814101A (en) * | 2000-08-24 | 2002-03-04 | Bio Rad Laboratories | Dry powder formulation for protein labeling |
KR100869784B1 (ko) * | 2002-01-08 | 2008-11-21 | 삼성에스디아이 주식회사 | 생체물질 고정용 발색 화합물 및 이를 이용한 생체물질고정용 코팅막 제조방법 |
US20060228723A1 (en) * | 2002-01-16 | 2006-10-12 | Keith Bradley | System and method for electronic sensing of biomolecules |
US20070178477A1 (en) * | 2002-01-16 | 2007-08-02 | Nanomix, Inc. | Nanotube sensor devices for DNA detection |
JP2008511008A (ja) * | 2004-08-24 | 2008-04-10 | ナノミックス・インコーポレーテッド | Dna検出用ナノチューブセンサー装置 |
EP2261656A4 (en) * | 2008-03-21 | 2014-04-09 | Arkray Inc | DRY TEST INSTRUMENT, METAL MEASURING METHOD, AND METHOD FOR MANUFACTURING DRY TEST INSTRUMENT |
US8455211B2 (en) * | 2010-07-15 | 2013-06-04 | Medical Diagnostic Laboratories, Llc | Anaplasma translocated substrate-1 (ATS-1) and sero-detection of Anaplasma phagocytophilum |
CN112710859A (zh) * | 2020-12-07 | 2021-04-27 | 珠海贝索生物技术有限公司 | 一种便于观察的Rh血型抗原检测方法 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3619371A (en) * | 1967-07-03 | 1971-11-09 | Nat Res Dev | Production of a polymeric matrix having a biologically active substance bound thereto |
US3646346A (en) * | 1968-12-26 | 1972-02-29 | Pharmacia Ab | Antibody-coated tube system for radioimmunoassay |
US3996344A (en) * | 1972-05-15 | 1976-12-07 | Biological Developments, Inc. | Phenethylamine antigenic conjugates, their preparation, antibodies and use |
US4090919A (en) * | 1976-01-29 | 1978-05-23 | Tanabe Seiyaku Co., Ltd. | Water-insoluble tannin preparation for immobilization of proteins |
US4108974A (en) * | 1976-08-27 | 1978-08-22 | Bio-Rad Laboratories, Inc. | Radioimmunoassay for thyroid hormone |
CA1144858A (en) * | 1979-06-13 | 1983-04-19 | Albert Venturini | Blood samples or stroma bonded through a diazoamino bond to a polymer |
IT1123573B (it) * | 1979-09-10 | 1986-04-30 | Anic Spa | Composizione adatta al controllo di tessuti e/o liquidi biiologici e metodo impiegante la stessa |
NL8000173A (nl) * | 1980-01-11 | 1981-08-03 | Akzo Nv | Toepassing van in water dispergeerbare, hydrofobe kleurstoffen als label in immunochemische testen. |
US4360358A (en) * | 1980-03-07 | 1982-11-23 | Yash Sharma | Immunoassay with solid phase having coating containing blood platelet substitute |
DE3014563A1 (de) * | 1980-04-16 | 1981-10-29 | Merck Patent Gmbh, 6100 Darmstadt | Verfahren zur bestimmung leukaemischer zellen |
US4604348A (en) * | 1981-11-19 | 1986-08-05 | New York Blood Center, Inc. | Composition for use in immunoassays |
JPH0665987B2 (ja) * | 1982-11-19 | 1994-08-24 | 富士写真フイルム株式会社 | 分析要素 |
DE3311889A1 (de) * | 1983-03-31 | 1984-10-11 | Byk-Mallinckrodt Chemische Produkte Gmbh, 6057 Dietzenbach | Verfahren zur irreversiblen bindung von protein an polystyroloberflaechen unter erhaltung der biologischen aktivitaet, so erhaltene polystyroloberflaechen und ihre verwendung |
DE3323645A1 (de) * | 1983-07-01 | 1985-01-10 | Biotest-Serum-Institut Gmbh, 6000 Frankfurt | Diagnostisches testsystem |
US4853210A (en) * | 1984-04-27 | 1989-08-01 | Cytocolor, Inc. | Method of staining cells with a diazo dye and compositions thereof |
US4714606A (en) * | 1984-05-15 | 1987-12-22 | Cytocolor Incorporated | Method of staining and identifying cells and compositions thereof |
GB8423204D0 (en) * | 1984-09-14 | 1984-10-17 | Comtech Res Unit | Assay technique and equipment |
US4792521A (en) * | 1985-08-15 | 1988-12-20 | Immunomedics, Inc. | Non-enzymatic immunohistochemical staining system and reagents |
US4853186A (en) * | 1986-05-30 | 1989-08-01 | Eastman Kodak Company | Water-compatible reducible compounds and their use in analytical compositions and methods |
JPS6394994A (ja) * | 1986-10-09 | 1988-04-26 | Fuji Photo Film Co Ltd | 酸化型補酵素含有乾式分析要素 |
US4783401A (en) * | 1986-10-31 | 1988-11-08 | Smithkline Beckman Corporation | Viable cell labelling |
US4855240A (en) * | 1987-05-13 | 1989-08-08 | Becton Dickinson And Company | Solid phase assay employing capillary flow |
US5047321A (en) * | 1988-06-15 | 1991-09-10 | Becton Dickinson & Co. | Method for analysis of cellular components of a fluid |
-
1988
- 1988-07-05 US US07/215,041 patent/US4963478A/en not_active Expired - Lifetime
-
1989
- 1989-06-04 CA CA000604701A patent/CA1340575C/en not_active Expired - Lifetime
- 1989-06-29 NZ NZ229765A patent/NZ229765A/en unknown
- 1989-07-03 AT AT89306717T patent/ATE112631T1/de not_active IP Right Cessation
- 1989-07-03 ES ES89306717T patent/ES2063132T3/es not_active Expired - Lifetime
- 1989-07-03 DE DE68918643T patent/DE68918643T2/de not_active Expired - Lifetime
- 1989-07-03 EP EP89306717A patent/EP0350233B1/en not_active Expired - Lifetime
- 1989-07-04 JP JP1171354A patent/JP2732124B2/ja not_active Expired - Lifetime
- 1989-07-05 AU AU37897/89A patent/AU619019B2/en not_active Expired
-
1993
- 1993-08-18 US US08/109,011 patent/US5468618A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE68918643D1 (de) | 1994-11-10 |
US5468618A (en) | 1995-11-21 |
ATE112631T1 (de) | 1994-10-15 |
US4963478A (en) | 1990-10-16 |
NZ229765A (en) | 1991-05-28 |
CA1340575C (en) | 1999-06-01 |
JPH0264460A (ja) | 1990-03-05 |
EP0350233A3 (en) | 1990-11-22 |
AU619019B2 (en) | 1992-01-16 |
EP0350233A2 (en) | 1990-01-10 |
EP0350233B1 (en) | 1994-10-05 |
AU3789789A (en) | 1990-01-11 |
DE68918643T2 (de) | 1995-02-09 |
JP2732124B2 (ja) | 1998-03-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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