ES2062175T3 - Medicamentos y productos dieteticos con contenido de nuevos derivados de acilaminoacidos. - Google Patents

Medicamentos y productos dieteticos con contenido de nuevos derivados de acilaminoacidos.

Info

Publication number
ES2062175T3
ES2062175T3 ES90109962T ES90109962T ES2062175T3 ES 2062175 T3 ES2062175 T3 ES 2062175T3 ES 90109962 T ES90109962 T ES 90109962T ES 90109962 T ES90109962 T ES 90109962T ES 2062175 T3 ES2062175 T3 ES 2062175T3
Authority
ES
Spain
Prior art keywords
novel
acid derivatives
medicines
derivatives
acilaminoacid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90109962T
Other languages
English (en)
Inventor
Klaus Gerling
Henning Heinemann
Andreas Meier
Klaus Langer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kabi Pharmacia GmbH
Kali Chemie AG
Original Assignee
Kabi Pharmacia GmbH
Kali Chemie AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia GmbH, Kali Chemie AG filed Critical Kabi Pharmacia GmbH
Application granted granted Critical
Publication of ES2062175T3 publication Critical patent/ES2062175T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
    • C07C235/74—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/03—Organic compounds
    • A23L29/045—Organic compounds containing nitrogen as heteroatom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE DESCRIBEN NUEVOS DERIVADOS DE ACILOAMINOACIDOS CARBOXILICOS DE FORMULA GENERAL I (FORMULA) EN LA QUE R1-R3 Y Z1, Z2 TIENEN EL SIGNIFICADO DADO EN LA DESCRIPCION. ESTOS PRODUCTOS POSEEN VALIOSAS PROPIEDADES FARMACOLOGICAS QUE INFLUYEN FAVORABLEMENTE SOBRE EL METABOLISMO DEL NITROGENO. TAMBIEN SE DESCRIBE LA UTILIZACION DE LOS NUEVOS DERIVADOS COMO PRODUCTOS FARMACEUTICOS Y DEITETICOS, SOBRE TODO PARA EL TRATAMIENTO Y PROFILAXIS DE DISTORSIONES DEL METABOLISMO DEL NITROGENO ORIGINADAS POR LESIONES HEPATICAS Y/O RENALES EN LOS MAMIFEROS SUPERIORES Y EN EL HOMBRE, ASI COMO LOS MEDICAMENTOS Y PRODUCTOS DIETETICOS QUE COMO SUSTANCIA ACTIVA CONTIENEN ESTOS NUEVOS DERIVADOS.
ES90109962T 1989-06-01 1990-05-25 Medicamentos y productos dieteticos con contenido de nuevos derivados de acilaminoacidos. Expired - Lifetime ES2062175T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3917880A DE3917880A1 (de) 1989-06-01 1989-06-01 Neue acylaminosaeurederivate enthaltende arzneimittel und diaetetika

Publications (1)

Publication Number Publication Date
ES2062175T3 true ES2062175T3 (es) 1994-12-16

Family

ID=6381852

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90109962T Expired - Lifetime ES2062175T3 (es) 1989-06-01 1990-05-25 Medicamentos y productos dieteticos con contenido de nuevos derivados de acilaminoacidos.

Country Status (7)

Country Link
US (1) US5089492A (es)
EP (1) EP0400499B1 (es)
JP (1) JP2716572B2 (es)
AT (1) ATE103890T1 (es)
DE (2) DE3917880A1 (es)
DK (1) DK0400499T3 (es)
ES (1) ES2062175T3 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE116285T1 (de) * 1990-09-28 1995-01-15 Kyowa Hakko Kogyo Kk Verfahren zur herstellung von kristallen eines salzes von sauerer aminosäure und basischer aminosäure.
US5256697A (en) * 1992-04-16 1993-10-26 Abbott Laboratories Method of administering pyruvate and methods of synthesizing pyruvate precursors
CA2219944A1 (en) * 1995-05-19 1996-11-21 Miho Kobayashi 2-hydroxyphenylalkylamine derivatives and maillard reaction inhibitors
DE10204951A1 (de) * 2002-02-06 2003-08-14 Basf Ag Phenylalaninderivate als Herbizide
US7745489B2 (en) * 2002-03-07 2010-06-29 The Regents Of The University Of California Compositions and methods for inhibition of phospholipase A2 mediated inflammation
DE102006055470A1 (de) * 2006-11-24 2008-05-29 Evonik Degussa Gmbh Ketomethioninketale und deren Derivate
CN104311409B (zh) * 2014-09-10 2016-03-09 河北一品制药有限公司 一种α-酮缬氨酸钙的制备工艺

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2556593B1 (fr) * 1983-12-20 1987-01-02 Synthelabo Composition nutritive contenant de l'acide alpha-cetoisocaproique, de la leucine et des acides amines essentiels et non essentiels
IT1206078B (it) * 1987-06-03 1989-04-14 Polifarma Spa Procedimento per la produzione di acido 3-indolpiruvico e suoi derivati loro uso farmaceutico

Also Published As

Publication number Publication date
JP2716572B2 (ja) 1998-02-18
EP0400499B1 (de) 1994-04-06
EP0400499A2 (de) 1990-12-05
US5089492A (en) 1992-02-18
JPH0334960A (ja) 1991-02-14
DE3917880A1 (de) 1990-12-06
EP0400499A3 (de) 1991-07-31
DK0400499T3 (da) 1994-05-09
DE59005233D1 (de) 1994-05-11
ATE103890T1 (de) 1994-04-15

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