ES2058892T3 - Uso de omeprazol como agente antimicrobiano. - Google Patents
Uso de omeprazol como agente antimicrobiano.Info
- Publication number
- ES2058892T3 ES2058892T3 ES90902854T ES90902854T ES2058892T3 ES 2058892 T3 ES2058892 T3 ES 2058892T3 ES 90902854 T ES90902854 T ES 90902854T ES 90902854 T ES90902854 T ES 90902854T ES 2058892 T3 ES2058892 T3 ES 2058892T3
- Authority
- ES
- Spain
- Prior art keywords
- omeprazole
- antimicrobial agent
- metoxi
- benzoimidiazole
- campilobacter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- SUBDBMMJDZJVOS-UHFFFAOYSA-N 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole Chemical compound N=1C2=CC(OC)=CC=C2NC=1S(=O)CC1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-UHFFFAOYSA-N 0.000 title 1
- 239000004599 antimicrobial Substances 0.000 title 1
- 229960000381 omeprazole Drugs 0.000 title 1
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical class [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
USO DE 5-METOXI-2-[[(4-METOXI-3,5-DIMETIL-2-PIRIDINILO) METILO]-1H-BENZOIMIDIAZOL O UNA SAL FARMACEUTICAMENTE ACEPTABLE DE EL EN EL TRATAMIENTO DE ENFERMEDADES INFECCIOSAS, ESPECIALES EN AQUELLAS CAUSADAS POR "CAMPILOBACTER PILORI".
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1030311A JP2694361B2 (ja) | 1989-02-09 | 1989-02-09 | 抗菌剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2058892T3 true ES2058892T3 (es) | 1994-11-01 |
Family
ID=12300238
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90902854T Expired - Lifetime ES2058892T3 (es) | 1989-02-09 | 1990-02-02 | Uso de omeprazol como agente antimicrobiano. |
Country Status (19)
Country | Link |
---|---|
US (1) | US5093342A (es) |
EP (1) | EP0414847B1 (es) |
JP (1) | JP2694361B2 (es) |
KR (1) | KR0140236B1 (es) |
AT (1) | ATE94063T1 (es) |
AU (1) | AU626641B2 (es) |
CA (1) | CA2025668C (es) |
CY (1) | CY1909A (es) |
DE (1) | DE69003207T2 (es) |
DK (1) | DK0414847T3 (es) |
ES (1) | ES2058892T3 (es) |
HK (1) | HK52196A (es) |
HU (1) | HU205253B (es) |
IE (1) | IE65814B1 (es) |
IL (1) | IL93263A0 (es) |
LV (1) | LV10577B (es) |
MY (1) | MY111737A (es) |
PH (1) | PH26787A (es) |
WO (1) | WO1990009175A1 (es) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0382489B1 (en) * | 1989-02-10 | 1994-11-17 | Takeda Chemical Industries, Ltd. | Use of benzimidazole derivatives as antibacterial agents |
GB9018603D0 (en) * | 1990-08-24 | 1990-10-10 | Smith Kline French Lab | Compositions |
DK0548103T3 (da) * | 1990-09-14 | 2002-04-02 | Byk Gulden Lomberg Chem Fab | Anvendelse af pyridylmethylsulfinyl-1H-benzimidazolderivater til behandling af sygdomme, der er fremkaldt af Helicobacter-bakterier |
IS3990A (is) * | 1992-04-24 | 1993-10-25 | Ab Astra | Aðferð við að blanda saman efni sem hindrar flæðimagasýru og bakteríueyðandi efnis sem brotnar niður í súru umhverfi |
US5504082A (en) * | 1992-06-01 | 1996-04-02 | Yoshitomi Pharmaceutical Industries, Ltd. | Pyridine compound and pharmaceutical compostions |
EP0673246A1 (de) * | 1992-12-10 | 1995-09-27 | Byk Gulden Lomberg Chemische Fabrik GmbH | Verwendung von alkylthiopyridinen zur bekämpfung von heliobacter-bakterien |
US6902738B2 (en) * | 1994-05-02 | 2005-06-07 | Josman Laboratories, Inc. | Topical oral dosage forms containing bismuth compounds |
US6426085B1 (en) | 1994-05-02 | 2002-07-30 | Josman Laboratories Inc. | Use of bismuth-containing compounds in topical oral dosage forms for the treatment of halitosis |
US5834002A (en) | 1994-05-02 | 1998-11-10 | Josman Laboratories, Inc. | Chewing gum containing colloidal bismuth subcitrate |
US6372784B1 (en) | 1995-02-07 | 2002-04-16 | Josman Laboratories, Inc. | Bismuth-containing compounds in topical dosage forms for treatment of corneal and dermal wounds |
US6379651B1 (en) | 1995-02-07 | 2002-04-30 | Josman Laboratories | Oral-topical dosage forms for delivering antibacterials/antibiotics to oral cavity to eradicate H. pylori as a concomitant treatment for peptic ulcers and other gastro-intestinal diseases |
WO1996024341A1 (en) * | 1995-02-07 | 1996-08-15 | Narayan Krishnarao Athanikar | Concomitant treatment with bismuth and antibacterials |
US5708017A (en) * | 1995-04-04 | 1998-01-13 | Merck & Co., Inc. | Stable, ready-to-use pharmaceutical paste composition containing proton pump inhibitors |
US6489346B1 (en) * | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
US6699885B2 (en) | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
US6645988B2 (en) * | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
SI9700186B (sl) | 1997-07-14 | 2006-10-31 | Lek, Tovarna Farmacevtskih In Kemicnih Izdelkov, D.D. | Nova farmacevtska oblika z nadzorovanim sproscanjem zdravilnih ucinkovin |
US6174548B1 (en) | 1998-08-28 | 2001-01-16 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
US6096340A (en) * | 1997-11-14 | 2000-08-01 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
EE04576B1 (et) * | 1997-12-08 | 2006-02-15 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Suposiit happes ebapüsivate toimeainete tarbeks, selle valmistamismeetod, toimeaineühik ja selle valmistamismeetod ning preparaat |
US6861448B2 (en) * | 1998-01-14 | 2005-03-01 | Virtual Drug Development, Inc. | NAD synthetase inhibitors and uses thereof |
ATE271555T1 (de) | 1998-01-14 | 2004-08-15 | Uab Research Foundation | Verfahren zur herstellung und screening von inhibitoren des bakteriellen nad synthetase enzyms, verbindungen daraus und methoden zur behandlung bakterieller und mikrobieller infektionen mit diesen inhibitoren |
US6733778B1 (en) | 1999-08-27 | 2004-05-11 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
US6245913B1 (en) | 1999-06-30 | 2001-06-12 | Wockhardt Europe Limited | Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole |
US6369087B1 (en) | 1999-08-26 | 2002-04-09 | Robert R. Whittle | Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
US6268385B1 (en) | 1999-08-26 | 2001-07-31 | Robert R. Whittle | Dry blend pharmaceutical formulations |
US6262085B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
US6780880B1 (en) | 1999-08-26 | 2004-08-24 | Robert R. Whittle | FT-Raman spectroscopic measurement |
US6262086B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Pharmaceutical unit dosage form |
US6312712B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Method of improving bioavailability |
US6326384B1 (en) | 1999-08-26 | 2001-12-04 | Robert R. Whittle | Dry blend pharmaceutical unit dosage form |
US6316020B1 (en) | 1999-08-26 | 2001-11-13 | Robert R. Whittle | Pharmaceutical formulations |
US6312723B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Pharmaceutical unit dosage form |
US6787342B2 (en) | 2000-02-16 | 2004-09-07 | Merial Limited | Paste formulations |
SE0002476D0 (sv) | 2000-06-30 | 2000-06-30 | Astrazeneca Ab | New compounds |
EP1554572B1 (en) | 2001-07-25 | 2009-10-14 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
JP2005521662A (ja) * | 2002-01-25 | 2005-07-21 | サンタラス インコーポレイティッド | プロトンポンプ阻害剤の経粘膜送達 |
JP2006518751A (ja) * | 2003-02-20 | 2006-08-17 | サンタラス インコーポレイティッド | 胃酸の急速かつ持続的な抑制のための新規製剤、オメプラゾール制酸剤複合体−即時放出物 |
US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
CA2531564C (en) * | 2003-07-18 | 2016-01-19 | Santarus, Inc. | Pharmaceutical composition for inhibiting acid secretion |
US20050031700A1 (en) * | 2003-07-18 | 2005-02-10 | Sanatarus, Inc. | Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders |
US20070292498A1 (en) * | 2003-11-05 | 2007-12-20 | Warren Hall | Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers |
US8815916B2 (en) | 2004-05-25 | 2014-08-26 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US8906940B2 (en) | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
EP3827747A1 (en) | 2005-04-28 | 2021-06-02 | Otsuka Pharmaceutical Co., Ltd. | Pharma-informatics system |
ES2374730T3 (es) | 2006-03-10 | 2012-02-21 | Arigen Pharmaceuticals, Inc. | Nuevo derivado de piridina que tiene actividad contra helicobacter pylori. |
EP2063905B1 (en) | 2006-09-18 | 2014-07-30 | Raptor Pharmaceutical Inc | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
EP2068841B1 (en) | 2006-10-05 | 2018-09-26 | Santarus, Inc. | Novel formulations of proton pump inhibitors and methods of using these formulations |
US20090092658A1 (en) * | 2007-10-05 | 2009-04-09 | Santarus, Inc. | Novel formulations of proton pump inhibitors and methods of using these formulations |
US20080103169A1 (en) | 2006-10-27 | 2008-05-01 | The Curators Of The University Of Missouri | Compositions comprising acid labile proton pump inhibiting agents, at least one other pharmaceutically active agent and methods of using same |
PL2103608T3 (pl) | 2006-12-18 | 2013-02-28 | Link Genomics Inc | Środek do eradykacji Helicobacter pylori mający działanie hamujące na sekrecję kwasu żołądkowego |
NZ616673A (en) | 2009-02-20 | 2014-08-29 | To Bbb Holding B V | Glutathione-based drug delivery system |
RU2484089C1 (ru) | 2009-04-09 | 2013-06-10 | Ариджен Фармасьютикалз, Инк. | Тиопроизводное пиридина и фармацевтическая композиция, которая его содержит и имеет способность действовать против helicobacter pylori |
ES2942923T3 (es) | 2009-05-06 | 2023-06-07 | Laboratory Skin Care Inc | Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas |
US8722026B2 (en) * | 2010-01-06 | 2014-05-13 | Elc Management, Llc | Skin lightening compositions |
US8992897B2 (en) | 2010-01-06 | 2015-03-31 | Elc Management Llc | Skin lightening compositions |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
KR101628474B1 (ko) * | 2014-08-27 | 2016-06-08 | 경북대학교 산학협력단 | 오메프라졸을 유효성분으로 포함하는 피부 미백용 화장료 조성물 |
WO2024075017A1 (en) | 2022-10-04 | 2024-04-11 | Zabirnyk Arsenii | Inhibition of aortic valve calcification |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
US4359465A (en) * | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
SE8301182D0 (sv) * | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
WO1989003830A1 (en) * | 1987-10-30 | 1989-05-05 | Aktiebolaget Hässle | 2-pyridinylmethyl (sulfinyl or thio)benzimidazoles for treatment of diseases related to bone loss |
-
1989
- 1989-02-09 JP JP1030311A patent/JP2694361B2/ja not_active Expired - Lifetime
-
1990
- 1990-02-02 IL IL93263A patent/IL93263A0/xx not_active IP Right Cessation
- 1990-02-02 ES ES90902854T patent/ES2058892T3/es not_active Expired - Lifetime
- 1990-02-02 KR KR1019900702221A patent/KR0140236B1/ko not_active IP Right Cessation
- 1990-02-02 EP EP90902854A patent/EP0414847B1/en not_active Expired - Lifetime
- 1990-02-02 DK DK90902854.0T patent/DK0414847T3/da active
- 1990-02-02 AU AU50381/90A patent/AU626641B2/en not_active Ceased
- 1990-02-02 US US07/572,951 patent/US5093342A/en not_active Expired - Fee Related
- 1990-02-02 DE DE90902854T patent/DE69003207T2/de not_active Expired - Fee Related
- 1990-02-02 WO PCT/SE1990/000070 patent/WO1990009175A1/en active IP Right Grant
- 1990-02-02 AT AT90902854T patent/ATE94063T1/de not_active IP Right Cessation
- 1990-02-02 CA CA002025668A patent/CA2025668C/en not_active Expired - Lifetime
- 1990-02-02 HU HU901539A patent/HU205253B/hu not_active IP Right Cessation
- 1990-02-02 CY CY190990A patent/CY1909A/xx unknown
- 1990-02-06 IE IE41890A patent/IE65814B1/en not_active IP Right Cessation
- 1990-02-09 MY MYPI90000213A patent/MY111737A/en unknown
- 1990-02-09 PH PH40033A patent/PH26787A/en unknown
-
1994
- 1994-08-30 LV LVP-94-169A patent/LV10577B/en unknown
-
1996
- 1996-03-21 HK HK52196A patent/HK52196A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR910700048A (ko) | 1991-03-13 |
WO1990009175A1 (en) | 1990-08-23 |
DE69003207D1 (de) | 1993-10-14 |
AU5038190A (en) | 1990-09-05 |
AU626641B2 (en) | 1992-08-06 |
LV10577B (en) | 1995-10-20 |
IL93263A0 (en) | 1990-11-29 |
DE69003207T2 (de) | 1994-02-03 |
MY111737A (en) | 2000-12-30 |
LV10577A (lv) | 1995-04-20 |
HUT54890A (en) | 1991-04-29 |
EP0414847B1 (en) | 1993-09-08 |
US5093342A (en) | 1992-03-03 |
CA2025668C (en) | 1998-09-15 |
JP2694361B2 (ja) | 1997-12-24 |
PH26787A (en) | 1992-10-13 |
EP0414847A1 (en) | 1991-03-06 |
IE900418L (en) | 1990-08-09 |
HU205253B (en) | 1992-04-28 |
HK52196A (en) | 1996-03-29 |
CA2025668A1 (en) | 1990-08-10 |
ATE94063T1 (de) | 1993-09-15 |
HU901539D0 (en) | 1991-02-28 |
KR0140236B1 (ko) | 1998-06-01 |
DK0414847T3 (da) | 1993-12-13 |
JPH02209809A (ja) | 1990-08-21 |
IE65814B1 (en) | 1995-11-15 |
CY1909A (en) | 1990-02-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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