ES2058627T3 - Sistema terapeutico para la administracion retardada y dirigida a traves de la piel o de las mucosas de sustancias activas. - Google Patents
Sistema terapeutico para la administracion retardada y dirigida a traves de la piel o de las mucosas de sustancias activas.Info
- Publication number
- ES2058627T3 ES2058627T3 ES90102771T ES90102771T ES2058627T3 ES 2058627 T3 ES2058627 T3 ES 2058627T3 ES 90102771 T ES90102771 T ES 90102771T ES 90102771 T ES90102771 T ES 90102771T ES 2058627 T3 ES2058627 T3 ES 2058627T3
- Authority
- ES
- Spain
- Prior art keywords
- active substance
- layer
- reservoir
- active substances
- mucous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Materials For Medical Uses (AREA)
Abstract
SE PRESENTA UN SISTEMA TERAPEUTICO PARA EL SUMINISTRO TRANSDERMAL O TRANSMUCOSAL RETARDADO Y CONTROLADO DE SUSTANCIAS ACTIVADORAS QUE SE COMPONE DE UNA CAPA TRASERA IMPERMEABLE, UN DEPOSITO QUE CONTIENE UNA SUSTANCIA ACTIVADORA, UNA CAPA ESENCIALMENTE EXENTA DE, PERO PERMEABLE PARA LA SUSTANCIA ACTIVADORA Y UNA CAPA PROTECTORA DESPRENDIBLE. LA CAPA EXENTA DE SUSTANCIA ACTIVADORA SE PONE EN CONTACTO CON EL DEPOSITO DE SUSTANCIA ACTIVADORA, INMEDIATAMENTE ANTES O DESPUES DE LA APLICACION, Y PARA ESO SE SITUA ENTRE EL DEPOSITO Y LA SUPERFICIE DE APLICACION. AL DIFUNDIRSE LA SUSTANCIA ACTIVADORA DEL DEPOSITO A LA CAPA EXENTA, AL MENOS UNA PARTE DE ESTA SUSTANCIA SE TRANSFORMA A UN ESTADO NO BIODISPONIBLE. ESTA TRANSFORMACION SE PUEDE LLEVAR A CABO INMOVILIZANDO LA SUSTANCIA MEDIANTE UNA REACCION QUIMICA O UN EFECTO RECIPROCO FISICO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3905051A DE3905051A1 (de) | 1989-02-18 | 1989-02-18 | Therapeutisches system zur verzoegerten und gesteuerten transdermalen oder transmucosalen verabreichung von wirkstoffen (i) |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2058627T3 true ES2058627T3 (es) | 1994-11-01 |
Family
ID=6374443
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90102771T Expired - Lifetime ES2058627T3 (es) | 1989-02-18 | 1990-02-13 | Sistema terapeutico para la administracion retardada y dirigida a traves de la piel o de las mucosas de sustancias activas. |
Country Status (8)
Country | Link |
---|---|
US (1) | US5215751A (es) |
EP (1) | EP0384267B1 (es) |
JP (1) | JP2538372B2 (es) |
AT (1) | ATE89756T1 (es) |
CA (1) | CA2010225C (es) |
DE (2) | DE3905051A1 (es) |
DK (1) | DK0384267T3 (es) |
ES (1) | ES2058627T3 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUT65957A (en) † | 1992-03-17 | 1994-08-29 | Becton Dickinson Co | User operated iontophoretical device and method for manufacturing it |
AU5354994A (en) * | 1992-10-15 | 1994-05-09 | Alza Corporation | Delayed onset transdermal delivery device |
DE4301781C2 (de) * | 1993-01-23 | 1995-07-20 | Lohmann Therapie Syst Lts | Nitroglycerinhaltiges Pflaster, Verfahren zu seiner Herstellung und Verwendung |
AU4657896A (en) * | 1995-01-19 | 1996-08-07 | Cygnus, Inc. | Polyisobutylene adhesives containing high TG tackifier for transdermal devices |
US5730721A (en) | 1996-01-25 | 1998-03-24 | Vesture Corporation | Medical applicator and method |
DE19814083C2 (de) | 1998-03-30 | 2002-02-07 | Lohmann Therapie Syst Lts | Verfahren zur Herstellung von transdermalen therapeutischen Systemen unter Verwendung von basischen Alkalimetallsalzen zur Umwandlung von Wirkstoffsalzen in die freien Basen |
DE19814087A1 (de) * | 1998-03-30 | 1999-10-14 | Lohmann Therapie Syst Lts | Feuchtigkeitsaktivierbares therapeutisches System |
DE19943317C1 (de) | 1999-09-10 | 2001-03-15 | Lohmann Therapie Syst Lts | Kunststofffolien, insbesondere für die Verwendung in einem dermalen oder transdermalen therapeutischen System und Verfahren zu ihrer Herstellung |
KR100373447B1 (ko) * | 2000-07-04 | 2003-02-25 | 강진양 | 약용탄을 이용한 파프제 |
DE10141651B4 (de) * | 2001-08-24 | 2007-02-15 | Lts Lohmann Therapie-Systeme Ag | Transdermales Therapeutisches System (TTS) mit dem Wirkstoff Fentanyl und Verfahren zu seiner Herstellung |
JP2003300873A (ja) * | 2002-04-12 | 2003-10-21 | Nitto Denko Corp | 貼付剤およびその製造方法 |
DE102008013701A1 (de) * | 2008-03-11 | 2009-09-17 | Lts Lohmann Therapie-Systeme Ag | Transdermales Therapeutisches System mit stabilisierter Membran |
DE102009022915A1 (de) * | 2009-05-27 | 2010-12-09 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System mit gesteuertem Wirkstofffluss |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4810499A (en) * | 1984-10-01 | 1989-03-07 | Biotek, Inc. | Transdermal drug delivery system and method |
US4756710A (en) * | 1985-04-05 | 1988-07-12 | Merck & Co., Inc. | pH-Mediated drug delivery system |
US4645502A (en) * | 1985-05-03 | 1987-02-24 | Alza Corporation | Transdermal delivery of highly ionized fat insoluble drugs |
US4816258A (en) * | 1987-02-26 | 1989-03-28 | Alza Corporation | Transdermal contraceptive formulations |
EP0290262A3 (en) * | 1987-05-08 | 1990-12-12 | EASTMAN KODAK COMPANY (a New Jersey corporation) | Improved nitrate therapy for angina pectoris |
US4781924A (en) * | 1987-11-09 | 1988-11-01 | Alza Corporation | Transdermal drug delivery device |
-
1989
- 1989-02-18 DE DE3905051A patent/DE3905051A1/de active Granted
-
1990
- 1990-02-12 US US07/478,811 patent/US5215751A/en not_active Expired - Fee Related
- 1990-02-13 DE DE9090102771T patent/DE59001522D1/de not_active Expired - Fee Related
- 1990-02-13 DK DK90102771.4T patent/DK0384267T3/da active
- 1990-02-13 AT AT90102771T patent/ATE89756T1/de not_active IP Right Cessation
- 1990-02-13 EP EP90102771A patent/EP0384267B1/de not_active Expired - Lifetime
- 1990-02-13 ES ES90102771T patent/ES2058627T3/es not_active Expired - Lifetime
- 1990-02-14 JP JP2031656A patent/JP2538372B2/ja not_active Expired - Lifetime
- 1990-02-16 CA CA002010225A patent/CA2010225C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5215751A (en) | 1993-06-01 |
EP0384267A3 (en) | 1990-12-19 |
CA2010225A1 (en) | 1990-08-18 |
EP0384267B1 (de) | 1993-05-26 |
DE3905051A1 (de) | 1990-08-30 |
ATE89756T1 (de) | 1993-06-15 |
DK0384267T3 (da) | 1993-10-04 |
JPH02258717A (ja) | 1990-10-19 |
CA2010225C (en) | 1998-04-28 |
JP2538372B2 (ja) | 1996-09-25 |
DE59001522D1 (de) | 1993-07-01 |
EP0384267A2 (de) | 1990-08-29 |
DE3905051C2 (es) | 1991-08-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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