ES2058224T3 - Procedimiento para la hidrolisis enzimatica de compuestos alfa-aminoadipinil-monoaminicos. - Google Patents

Procedimiento para la hidrolisis enzimatica de compuestos alfa-aminoadipinil-monoaminicos.

Info

Publication number
ES2058224T3
ES2058224T3 ES88120945T ES88120945T ES2058224T3 ES 2058224 T3 ES2058224 T3 ES 2058224T3 ES 88120945 T ES88120945 T ES 88120945T ES 88120945 T ES88120945 T ES 88120945T ES 2058224 T3 ES2058224 T3 ES 2058224T3
Authority
ES
Spain
Prior art keywords
alpha
compounds
monoaminic
adipinyl
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88120945T
Other languages
English (en)
Inventor
Werner Dr Aretz
Klaus Dr Sauber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2058224T3 publication Critical patent/ES2058224T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/104Aminoacyltransferases (2.3.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/02Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by desacylation of the substituent in the 7 position

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

CON AYUDA DE (TAU) - GLUTAMILTRANSPEPTIDASA, QUE HA DE OBTENERSE FERMENTATIVAMENTE, SE PUEDEN HIDROLIZAR COMPUESTOS DE (ALFA) AMINOADIPINIL - MONOAMINO, ESPECIALMENTE D - ((DELTA)) - (ALFA) - AMINOADIPINIL 7 - AMINOCEFALOSPORANOACIDO.
ES88120945T 1987-12-21 1988-12-15 Procedimiento para la hidrolisis enzimatica de compuestos alfa-aminoadipinil-monoaminicos. Expired - Lifetime ES2058224T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873743323 DE3743323A1 (de) 1987-12-21 1987-12-21 Verfahren zur enzymatischen hydrolyse von (alpha)-aminoadipinyl-monoaminoverbindungen

Publications (1)

Publication Number Publication Date
ES2058224T3 true ES2058224T3 (es) 1994-11-01

Family

ID=6343136

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88120945T Expired - Lifetime ES2058224T3 (es) 1987-12-21 1988-12-15 Procedimiento para la hidrolisis enzimatica de compuestos alfa-aminoadipinil-monoaminicos.

Country Status (14)

Country Link
EP (1) EP0321849B1 (es)
JP (1) JP2816167B2 (es)
KR (1) KR0149656B1 (es)
AT (1) ATE91711T1 (es)
AU (1) AU616450B2 (es)
CA (1) CA1317246C (es)
CZ (1) CZ283529B6 (es)
DE (2) DE3743323A1 (es)
DK (1) DK710588A (es)
ES (1) ES2058224T3 (es)
HU (1) HU202917B (es)
IE (1) IE62566B1 (es)
PT (1) PT89282B (es)
ZA (1) ZA889442B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3881531D1 (de) * 1987-01-17 1993-07-15 Hoechst Ag Verwendung von gamma-glutamyl-transpeptidase.
US5229274A (en) * 1989-06-27 1993-07-20 Merck & Co., Inc. Gene encoding one step cephalosporin C amidase and expression thereof in recombinant bacillus
US5104800A (en) * 1989-06-27 1992-04-14 Merck & Co., Inc. One-step cephalosporin c amidase enzyme
JP3036775B2 (ja) * 1990-02-07 2000-04-24 協和醗酵工業株式会社 r―グルタミルトランスペプチダーゼの製造法
JPH04281787A (ja) * 1991-03-04 1992-10-07 Yoshihiro Asada γ−グルタミルトランスペプチターゼの製造方法
RO116648B1 (ro) * 1991-10-15 2001-04-30 Merck & Co Inc Bioprocedeu pentru prepararea acidului 7-amino-3-deacetil-cefalosporanic si a acidului 7-aminocefalosporanic

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6121097A (ja) * 1984-07-10 1986-01-29 Asahi Chem Ind Co Ltd 7−アミノセフアロスポラン酸及びその誘導体の製造法
DE3881531D1 (de) * 1987-01-17 1993-07-15 Hoechst Ag Verwendung von gamma-glutamyl-transpeptidase.

Also Published As

Publication number Publication date
HU202917B (en) 1991-04-29
ZA889442B (en) 1989-08-30
KR890010211A (ko) 1989-08-07
PT89282B (pt) 1993-07-30
PT89282A (pt) 1989-12-29
IE62566B1 (en) 1995-02-08
DE3743323A1 (de) 1989-06-29
DE3882503D1 (de) 1993-08-26
JP2816167B2 (ja) 1998-10-27
CZ283529B6 (cs) 1998-04-15
CA1317246C (en) 1993-05-04
AU616450B2 (en) 1991-10-31
HUT49168A (en) 1989-08-28
AU2732388A (en) 1989-06-22
JPH01199576A (ja) 1989-08-10
ATE91711T1 (de) 1993-08-15
CZ847388A3 (en) 1997-12-17
DK710588A (da) 1989-06-22
EP0321849A2 (de) 1989-06-28
DK710588D0 (da) 1988-12-20
KR0149656B1 (ko) 1998-08-17
EP0321849B1 (de) 1993-07-21
IE883807L (en) 1989-06-21
EP0321849A3 (en) 1990-09-12

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