ES2055407T3 - Analogos de acidos grasos oxi- o tio-sustituidos para ser utilizados en el tratamiento de infecciones retrovirales. - Google Patents
Analogos de acidos grasos oxi- o tio-sustituidos para ser utilizados en el tratamiento de infecciones retrovirales.Info
- Publication number
- ES2055407T3 ES2055407T3 ES90870135T ES90870135T ES2055407T3 ES 2055407 T3 ES2055407 T3 ES 2055407T3 ES 90870135 T ES90870135 T ES 90870135T ES 90870135 T ES90870135 T ES 90870135T ES 2055407 T3 ES2055407 T3 ES 2055407T3
- Authority
- ES
- Spain
- Prior art keywords
- treatment
- thio
- oxy
- retroviral infections
- analogs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/60—Unsaturated compounds containing ether groups, groups, groups, or groups the non-carboxylic part of the ether being unsaturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/006—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length of peptides containing derivatised side chain amino acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SUSTRATOS ANALOGOS DE ACIDO GRASO OXIDE ENZIMAS, CUYOS ANALOGOS CONTIENEN UN ATOMO DE OXIGENO, O DE AZUFRE, EN EL LUGAR DEL GRUPO METILENO, EN UNA POSICION DEL CARBONO ENTRE LA 4 Y LA 13 DE LA CADENA DE ACIDO GRASO, DE UN ACIDO GRASO DE C13-C14 O DE ALQUILO ESTERES DE EL, SE EMPLEAN PARA EL TRATAMIENTO DE INFECCIONES DE RETROVIRUS Y EN LA FABRICACION DE MEDICAMENTOS PARA EL TRATAMIENTO DE INFECCIONES DE RETROVIRUS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/402,094 US5073571A (en) | 1988-06-16 | 1989-09-01 | Method of inhibiting virus |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2055407T3 true ES2055407T3 (es) | 1994-08-16 |
Family
ID=23590495
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90870135T Expired - Lifetime ES2055407T3 (es) | 1989-09-01 | 1990-08-31 | Analogos de acidos grasos oxi- o tio-sustituidos para ser utilizados en el tratamiento de infecciones retrovirales. |
Country Status (8)
Country | Link |
---|---|
US (1) | US5073571A (es) |
EP (1) | EP0415902B1 (es) |
JP (1) | JPH0714875B2 (es) |
AT (1) | ATE86854T1 (es) |
CA (1) | CA2024489A1 (es) |
DE (1) | DE69001107T2 (es) |
DK (1) | DK0415902T3 (es) |
ES (1) | ES2055407T3 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE141644T1 (de) * | 1990-02-26 | 1996-09-15 | Univ Washington | Verfahren zur protein-n-myristoylation |
US5236955A (en) * | 1992-04-10 | 1993-08-17 | Washington University | Anti-fungal agent |
US6602861B1 (en) * | 1992-04-16 | 2003-08-05 | Research Corporation Technologies, Inc. | Acylated phospholipid drugs |
US5463152A (en) * | 1994-12-08 | 1995-10-31 | E. I. Du Pont De Nemours And Company | Halofluorocarbon hydrogenolysis |
GB2267642B (en) * | 1992-06-10 | 1996-04-24 | British Tech Group | Anti-viral agents |
GB9212276D0 (en) * | 1992-06-10 | 1992-07-22 | Harper David R | Anti-viral agents |
US5599947A (en) * | 1993-01-14 | 1997-02-04 | G. D. Searle & Co. | Fatty acid analogs and prodrugs |
US5859052A (en) * | 1993-01-14 | 1999-01-12 | G. D. Searle & Co. | Fatty acid analogs and prodrugs |
DE10063111A1 (de) * | 2000-12-18 | 2002-06-20 | Bayer Ag | Replikationsassay zur Auffindung antiviraler Substanzen |
CN103237546B (zh) | 2010-07-28 | 2016-06-08 | 生命科技公司 | 抗病毒的含有叠氮化物的化合物 |
US20120028335A1 (en) | 2010-07-28 | 2012-02-02 | Life Technologies Corporation | Anti-viral azide-containing compounds |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2262514A1 (en) * | 1974-03-01 | 1975-09-26 | Alary Josette | Reticulo-endothelial stimulating compsn. - contg. sodium oleate, sodium stearate and neutralised olive oil |
US4513005A (en) * | 1981-06-18 | 1985-04-23 | Lilly Industries Limited | SRS-A antagonists |
US4740588A (en) * | 1986-08-07 | 1988-04-26 | Washington University | Novel substrate peptides |
US4709012A (en) * | 1986-08-07 | 1987-11-24 | Washington University | Novel inhibitor peptides |
-
1989
- 1989-09-01 US US07/402,094 patent/US5073571A/en not_active Expired - Fee Related
-
1990
- 1990-08-31 EP EP90870135A patent/EP0415902B1/en not_active Expired - Lifetime
- 1990-08-31 JP JP2232269A patent/JPH0714875B2/ja not_active Expired - Lifetime
- 1990-08-31 AT AT90870135T patent/ATE86854T1/de not_active IP Right Cessation
- 1990-08-31 DK DK90870135.2T patent/DK0415902T3/da active
- 1990-08-31 CA CA002024489A patent/CA2024489A1/en not_active Abandoned
- 1990-08-31 ES ES90870135T patent/ES2055407T3/es not_active Expired - Lifetime
- 1990-08-31 DE DE90870135T patent/DE69001107T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0415902B1 (en) | 1993-03-17 |
JPH03109322A (ja) | 1991-05-09 |
US5073571A (en) | 1991-12-17 |
DE69001107T2 (de) | 1993-10-07 |
ATE86854T1 (de) | 1993-04-15 |
DK0415902T3 (da) | 1993-04-19 |
EP0415902A1 (en) | 1991-03-06 |
JPH0714875B2 (ja) | 1995-02-22 |
CA2024489A1 (en) | 1991-03-02 |
DE69001107D1 (de) | 1993-04-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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