ES2053797T3 - Procedimiento microbiano para la obtencion de derivados de milbemicina. - Google Patents
Procedimiento microbiano para la obtencion de derivados de milbemicina.Info
- Publication number
- ES2053797T3 ES2053797T3 ES88810049T ES88810049T ES2053797T3 ES 2053797 T3 ES2053797 T3 ES 2053797T3 ES 88810049 T ES88810049 T ES 88810049T ES 88810049 T ES88810049 T ES 88810049T ES 2053797 T3 ES2053797 T3 ES 2053797T3
- Authority
- ES
- Spain
- Prior art keywords
- image
- represent
- formulae
- milbemicine
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N49/00—Biocides, pest repellants or attractants, or plant growth regulators, containing compounds containing the group, wherein m+n>=1, both X together may also mean —Y— or a direct carbon-to-carbon bond, and the carbon atoms marked with an asterisk are not part of any ring system other than that which may be formed by the atoms X, the carbon atoms in square brackets being part of any acyclic or cyclic structure, or the group, wherein A means a carbon atom or Y, n>=0, and not more than one of these carbon atoms being a member of the same ring system, e.g. juvenile insect hormones or mimics thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/145—Fungal isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
- C12R2001/525—Streptomyces diastatochromogenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
- C12R2001/66—Aspergillus
- C12R2001/685—Aspergillus niger
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Insects & Arthropods (AREA)
- Botany (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A UN PROCEDIMIENTO MICROBIANO, DE UNA ETAPA, PARA OBTENCION DE 13 BETA-HIDROXI O 14,15-EPOXI-MILBEMICINAS DE LAS FORMULAS I Y II DONDE R1 Y RI SON METILO, ETILO, ISOPROPILO O SEC-BUTILO O EL GRUPO DE FORMULA VI DONDE X ES METILO, ETILO O ISOPROPILO, Y A Y A'' SON LOS GRUPOS DE FORMULA IV Y V DONDE R2 ES HIDROGENO, -C(O)-CH2O-C(O)-CH2CH2-COOH O -C(O)-CH2CH2-COOH O DE MEZCLAS DE COMPUESTOS DE FORMULA I Y II, CARACTERIZADO PORQUE UNA MILBEMICINA DISUELTA EN FASE LIQUIDA DE FORMUAL III, DONDE R3 ES R1 O RI Y R4 ES A O A'' Y R1, RI, A Y A'' TIENEN LOS SIGNIFICADOS DADOS EN LASFORMULAS I Y II. SE PONE EN CONTACTO CON UN MICROORGANISMO (O SUS COMPONENTES ACTIVOS) ADECUADO PARA 13 BETA-HIDROXILACION O 14,15-EPOXIDACION O PARA AMBAS REACCIONES. LOS MICROORGANISMOS O SUS COMPONENTES ACTIVOS PUEDEN ESTAR INCLUSO EN FORMA LIBRE O INMOVILIZADA
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH39587 | 1987-02-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2053797T3 true ES2053797T3 (es) | 1994-08-01 |
Family
ID=4186037
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88810049T Expired - Lifetime ES2053797T3 (es) | 1987-02-04 | 1988-01-29 | Procedimiento microbiano para la obtencion de derivados de milbemicina. |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0277916B1 (es) |
JP (2) | JP2719785B2 (es) |
AT (1) | ATE106081T1 (es) |
DE (1) | DE3889676D1 (es) |
DK (1) | DK54388A (es) |
ES (1) | ES2053797T3 (es) |
IL (1) | IL85292A0 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR243528A1 (es) * | 1986-12-11 | 1993-08-31 | Sankyo Co | Procedimiento para preparar compuestos de macrolida y un procedimiento para producir con los mismos una composicion parasiticida. |
US5212322A (en) * | 1986-12-11 | 1993-05-18 | Sankyo Company, Limited | Macrolide compounds, their preparation and their use |
GB8804440D0 (en) * | 1988-02-25 | 1988-03-23 | Pfizer Ltd | Antiparasitic agents |
CA1339481C (en) * | 1988-10-18 | 1997-09-30 | Shieh-Shung Tom Chen | Anthelmintic bioconversion products |
US5015630A (en) * | 1989-01-19 | 1991-05-14 | Merck & Co., Inc. | 5-oxime avermectin derivatives |
NZ232422A (en) * | 1989-02-16 | 1992-11-25 | Merck & Co Inc | 13-ketal milbemycin derivatives and parasiticides |
US5188944A (en) * | 1990-06-22 | 1993-02-23 | Merck & Co., Inc. | Process for the glycosylation of avermectin agylcones |
US5225338A (en) * | 1990-09-24 | 1993-07-06 | Merck & Co., Inc. | Microbial preparation of 13β-13-deoxy-22,23-dihydro avermectin-B1A/B1B aglycone |
CN114940907B (zh) * | 2022-01-05 | 2024-04-02 | 内蒙古工业大学 | 一种重金属污染土修复剂及其修复方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59108785A (ja) * | 1982-11-25 | 1984-06-23 | Sankyo Co Ltd | ミルベマイシン類の5−オキシム誘導体 |
US4696922A (en) * | 1984-11-26 | 1987-09-29 | Ciba-Geigy Corporation | 5-azolylacetoxymilbemycins as ecto- and endoparasites |
-
1988
- 1988-01-29 ES ES88810049T patent/ES2053797T3/es not_active Expired - Lifetime
- 1988-01-29 AT AT88810049T patent/ATE106081T1/de not_active IP Right Cessation
- 1988-01-29 DE DE3889676T patent/DE3889676D1/de not_active Expired - Fee Related
- 1988-01-29 EP EP88810049A patent/EP0277916B1/de not_active Expired - Lifetime
- 1988-02-02 IL IL85292A patent/IL85292A0/xx unknown
- 1988-02-03 DK DK054388A patent/DK54388A/da not_active Application Discontinuation
- 1988-02-04 JP JP63024878A patent/JP2719785B2/ja not_active Expired - Fee Related
-
1997
- 1997-06-30 JP JP9189034A patent/JP2838400B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2719785B2 (ja) | 1998-02-25 |
JP2838400B2 (ja) | 1998-12-16 |
ATE106081T1 (de) | 1994-06-15 |
JPS63216888A (ja) | 1988-09-09 |
JPH1066593A (ja) | 1998-03-10 |
EP0277916A2 (de) | 1988-08-10 |
IL85292A0 (en) | 1988-07-31 |
DE3889676D1 (de) | 1994-06-30 |
DK54388D0 (da) | 1988-02-03 |
EP0277916A3 (en) | 1989-10-25 |
DK54388A (da) | 1988-08-05 |
EP0277916B1 (de) | 1994-05-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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