ES2052670T3 - Utilizacion de derivados de 2-pirimidinil-1-piperazina. - Google Patents

Utilizacion de derivados de 2-pirimidinil-1-piperazina.

Info

Publication number
ES2052670T3
ES2052670T3 ES88117454T ES88117454T ES2052670T3 ES 2052670 T3 ES2052670 T3 ES 2052670T3 ES 88117454 T ES88117454 T ES 88117454T ES 88117454 T ES88117454 T ES 88117454T ES 2052670 T3 ES2052670 T3 ES 2052670T3
Authority
ES
Spain
Prior art keywords
pirimidinyl
piperazine derivatives
image
stands
animals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88117454T
Other languages
English (en)
Inventor
Klaus Prof Dr Opitz
Maria-Luise Dr Weischer
Jorg Dr Traber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Troponwerke GmbH
Original Assignee
Troponwerke GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Troponwerke GmbH filed Critical Troponwerke GmbH
Application granted granted Critical
Publication of ES2052670T3 publication Critical patent/ES2052670T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Abstract

DERIVADOS DE 2 - PIRIDINILO, 1 - PIPERACINA CONTENIDOS EN MEDICAMENTOS QUE PUEDEN SER UTILIZADOS PARA EL TRATAMIENTO DE DEPENDENCIA DE NICOTINA.
ES88117454T 1987-10-31 1988-10-20 Utilizacion de derivados de 2-pirimidinil-1-piperazina. Expired - Lifetime ES2052670T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873736974 DE3736974A1 (de) 1987-10-31 1987-10-31 Verwendung von 2-pyrimidinyl-1-piperazin-derivaten

Publications (1)

Publication Number Publication Date
ES2052670T3 true ES2052670T3 (es) 1994-07-16

Family

ID=6339509

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88117454T Expired - Lifetime ES2052670T3 (es) 1987-10-31 1988-10-20 Utilizacion de derivados de 2-pirimidinil-1-piperazina.

Country Status (10)

Country Link
US (1) US4871738A (es)
EP (1) EP0314984B1 (es)
JP (1) JP2618455B2 (es)
AT (1) ATE82850T1 (es)
DE (2) DE3736974A1 (es)
DK (1) DK601888A (es)
ES (1) ES2052670T3 (es)
FI (1) FI884960A (es)
HU (1) HU201676B (es)
IL (1) IL88222A0 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5185329A (en) * 1988-08-30 1993-02-09 Bristol-Myers Squibb Company Method for treatment of substance addiction
US5468749A (en) * 1988-08-30 1995-11-21 Gawin; Frank H. Method for treatment of substance addiction
IL91451A0 (en) * 1988-08-30 1990-04-29 Bristol Myers Co Pharmaceutical compositions comprising azapiron compounds and their use in the treatment of addiction
US4999382A (en) * 1988-10-26 1991-03-12 Massachusetts Institute Of Technology Compositions for treating tobacco withdrawal symptoms and methods for their use
US4957913A (en) * 1989-11-22 1990-09-18 American Home Products Corp. Antihypertensive polycyclic imides
US5162321A (en) * 1989-12-20 1992-11-10 Adir Et Compagnie 1-naphthyl piperazines useful as 5-HT1A receptor ligands
WO1992000075A1 (en) * 1990-06-29 1992-01-09 Pfizer Inc. Pyridopyrazine derivatives for treating substance abuse and addiction
US5633009A (en) * 1990-11-28 1997-05-27 Sano Corporation Transdermal administration of azapirones

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3976776A (en) * 1972-12-06 1976-08-24 Mead Johnson & Company Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones
US4182763A (en) * 1978-05-22 1980-01-08 Mead Johnson & Company Buspirone anti-anxiety method
US4438119A (en) * 1982-12-23 1984-03-20 Mead Johnson & Company Method for alleviation of extrapyramidal motor disorders
DE3321969A1 (de) * 1983-06-18 1984-12-20 Troponwerke GmbH & Co KG, 5000 Köln 2-pyrimidinyl-1-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4634703A (en) * 1985-10-25 1987-01-06 Bristol-Myers Company Method for alleviation of panic disorders
US4640921A (en) * 1986-02-04 1987-02-03 Bristol-Myers Treatment of sexual dysfunction with buspirone
US4687772A (en) * 1986-10-07 1987-08-18 Bristol-Myers Company Method for improvement of short term memory
US4777173A (en) * 1987-03-25 1988-10-11 Bristol-Myers Company Method for treatment of alcohol abuse

Also Published As

Publication number Publication date
DK601888A (da) 1989-05-01
IL88222A0 (en) 1989-06-30
HUT48119A (en) 1989-05-29
DE3736974A1 (de) 1989-05-11
US4871738A (en) 1989-10-03
FI884960A0 (fi) 1988-10-27
JPH0291070A (ja) 1990-03-30
JP2618455B2 (ja) 1997-06-11
EP0314984B1 (de) 1992-12-02
EP0314984A3 (de) 1991-01-09
FI884960A (fi) 1989-05-01
DK601888D0 (da) 1988-10-28
ATE82850T1 (de) 1992-12-15
HU201676B (en) 1990-12-28
DE3876381D1 (de) 1993-01-14
EP0314984A2 (de) 1989-05-10

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