ES2051909T3 - Vacuna del conjugado de polisacarido-proteina de membrana externa contra la haemophilus influenzae tipo b. - Google Patents

Vacuna del conjugado de polisacarido-proteina de membrana externa contra la haemophilus influenzae tipo b.

Info

Publication number
ES2051909T3
ES2051909T3 ES89104996T ES89104996T ES2051909T3 ES 2051909 T3 ES2051909 T3 ES 2051909T3 ES 89104996 T ES89104996 T ES 89104996T ES 89104996 T ES89104996 T ES 89104996T ES 2051909 T3 ES2051909 T3 ES 2051909T3
Authority
ES
Spain
Prior art keywords
influenzae type
vaccine
haemophilus influenzae
protein conjugate
daltons
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89104996T
Other languages
English (en)
Inventor
Joseph S-C Kuo
James Edwin Bristol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ES2051909T3 publication Critical patent/ES2051909T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

INMUNIZADOR CONJUGADO DE UNA PROTEINA DE MEMBRANA EXTERNA DE 38,000 A 40,000 DALTONS DE H. INFLAMARE TIPO B Y FRAGMENTOS POLISARIDIS DE FOSFATO VIBILOT-POLIVIBOSOL OXIDIZADO DE H. INFLAMARE TIPO B SON DESCUBIERTOS. VACUNAS QUE CONTIENEN LOS CONJUDASOS SON DESCUBIERTOS COMO UTILES EN INMUNIZACION CONTRA LA H. INFLAMARE. METODOS PARA CONSTAR Y PURIFICAR LAS PROTEINAS DE MEMBRANA EXTERNA DE 38,000 Y 40,000 Y PARA PREPARAR LOS FRAGMENTOS POLISACARIDOS DE FOSFATO VIBITL-POLIRIVOSIL EXIDAZADO SON TAMBIEN DESCUBIERTOS.
ES89104996T 1988-04-19 1989-03-21 Vacuna del conjugado de polisacarido-proteina de membrana externa contra la haemophilus influenzae tipo b. Expired - Lifetime ES2051909T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18320688A 1988-04-19 1988-04-19

Publications (1)

Publication Number Publication Date
ES2051909T3 true ES2051909T3 (es) 1994-07-01

Family

ID=22671900

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89104996T Expired - Lifetime ES2051909T3 (es) 1988-04-19 1989-03-21 Vacuna del conjugado de polisacarido-proteina de membrana externa contra la haemophilus influenzae tipo b.

Country Status (6)

Country Link
EP (1) EP0338265B1 (es)
JP (1) JPH0276824A (es)
AT (1) ATE105189T1 (es)
AU (1) AU627455B2 (es)
DE (1) DE68915046T2 (es)
ES (1) ES2051909T3 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0378929A3 (en) * 1988-12-23 1990-08-01 Connaught Laboratories Limited Membrane proteins and peptides of haemophilus influenzae type b
SE466259B (sv) * 1990-05-31 1992-01-20 Arne Forsgren Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal
DE69130955T2 (de) * 1990-12-21 1999-07-01 Antex Biolog Inc Adhesin-oligosaccharid-impfstoffkonjugate für -i(haemophilus influenza)
US5843463A (en) * 1990-12-21 1998-12-01 Antexbiologics, Inc. Adhesin-oligosaccharide conjugate vaccine for Haemophilus influenzae
CA2059693C (en) * 1991-01-28 2003-08-19 Peter J. Kniskern Polysaccharide antigens from streptococcus pneumoniae
CA2059692C (en) * 1991-01-28 2004-11-16 Peter J. Kniskern Pneumoccoccal polysaccharide conjugate vaccine
JP2805174B2 (ja) * 1992-06-22 1998-09-30 アンテックス バイオロジックス，インコーポレーテッド ヘモフィルス・インフルエンザ用アドヘシン−オリゴ糖複合体ワクチン
US5439808A (en) * 1993-07-23 1995-08-08 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
AUPM322393A0 (en) * 1993-12-24 1994-01-27 Austin Research Institute, The Mucin carbohydrate compounds and their use in immunotherapy
US5681570A (en) * 1995-01-12 1997-10-28 Connaught Laboratories Limited Immunogenic conjugate molecules
US5747287A (en) * 1995-04-28 1998-05-05 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
BR9811475A (pt) * 1997-07-17 2000-08-15 North American Vaccine Inc Conjugados imunogênicos compreendendo uma porina meningocóccica de grupo b e um polissacarìdeo de h. influenzae
CA3052621A1 (en) 2017-02-03 2018-08-09 Schadeck, Eva Barbara Haemophilus influenzae saccharide-carrier conjugate compositions and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4356170A (en) * 1981-05-27 1982-10-26 Canadian Patents & Development Ltd. Immunogenic polysaccharide-protein conjugates
US4673574A (en) * 1981-08-31 1987-06-16 Anderson Porter W Immunogenic conjugates
US4451446A (en) * 1982-03-04 1984-05-29 Smithkline-Rit Process for the preparation of polysaccharide-protein complexes from bacterial capsules, obtained products and immunogenic compositions containing them
US4623574A (en) * 1985-01-14 1986-11-18 Allied Corporation Ballistic-resistant composite article
US4707543A (en) * 1985-09-17 1987-11-17 The United States Of America As Represented By The Secretary Of The Army Process for the preparation of detoxified polysaccharide-outer membrane protein complexes, and their use as antibacterial vaccines
NZ223009A (en) * 1986-12-31 1990-06-26 Nl Rivm Of Thoven Oligosaccharides containing d-ribose d-ribitol and phosphate units mimicing haemophilus influenzae type b antigens

Also Published As

Publication number Publication date
DE68915046D1 (de) 1994-06-09
JPH0276824A (ja) 1990-03-16
AU627455B2 (en) 1992-08-27
DE68915046T2 (de) 1994-12-08
AU3313789A (en) 1989-10-26
ATE105189T1 (de) 1994-05-15
EP0338265A3 (en) 1989-12-13
EP0338265B1 (en) 1994-05-04
EP0338265A2 (en) 1989-10-25

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