ES2049546T3 - Procedimiento y dispositivo de regulacion de caudal de una protesis cardiaca de caudal periodico. - Google Patents
Procedimiento y dispositivo de regulacion de caudal de una protesis cardiaca de caudal periodico.Info
- Publication number
- ES2049546T3 ES2049546T3 ES91904121T ES91904121T ES2049546T3 ES 2049546 T3 ES2049546 T3 ES 2049546T3 ES 91904121 T ES91904121 T ES 91904121T ES 91904121 T ES91904121 T ES 91904121T ES 2049546 T3 ES2049546 T3 ES 2049546T3
- Authority
- ES
- Spain
- Prior art keywords
- flow
- procedure
- protesis
- prosthesis
- detector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/40—Details relating to driving
- A61M60/424—Details relating to driving for positive displacement blood pumps
- A61M60/427—Details relating to driving for positive displacement blood pumps the force acting on the blood contacting member being hydraulic or pneumatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
- A61M60/152—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel branching on and drawing blood from a blood vessel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/165—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable in, on, or around the heart
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/196—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body replacing the entire heart, e.g. total artificial hearts [TAH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/40—Details relating to driving
- A61M60/403—Details relating to driving for non-positive displacement blood pumps
- A61M60/419—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being permanent magnetic, e.g. from a rotating magnetic coupling between driving and driven magnets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/50—Details relating to control
- A61M60/508—Electronic control means, e.g. for feedback regulation
- A61M60/538—Regulation using real-time blood pump operational parameter data, e.g. motor current
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/50—Details relating to control
- A61M60/508—Electronic control means, e.g. for feedback regulation
- A61M60/538—Regulation using real-time blood pump operational parameter data, e.g. motor current
- A61M60/546—Regulation using real-time blood pump operational parameter data, e.g. motor current of blood flow, e.g. by adapting rotor speed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/50—Details relating to control
- A61M60/508—Electronic control means, e.g. for feedback regulation
- A61M60/538—Regulation using real-time blood pump operational parameter data, e.g. motor current
- A61M60/554—Regulation using real-time blood pump operational parameter data, e.g. motor current of blood pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/50—Details relating to control
- A61M60/508—Electronic control means, e.g. for feedback regulation
- A61M60/562—Electronic control means, e.g. for feedback regulation for making blood flow pulsatile in blood pumps that do not intrinsically create pulsatile flow
- A61M60/569—Electronic control means, e.g. for feedback regulation for making blood flow pulsatile in blood pumps that do not intrinsically create pulsatile flow synchronous with the native heart beat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3334—Measuring or controlling the flow rate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
- A61M60/148—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Mechanical Engineering (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- External Artificial Organs (AREA)
- Prostheses (AREA)
Abstract
LA INVENCION SE REFIERE A UN PROCESO Y A UN DISPOSITIVO QUE PERMITEN ADAPTAR EL FLUJO SANGUINEO CONDUCIDO POR UNA PROTESIS CARDIACA ACCIONADA POR UNA ACCIONADOR ELECTRICO (18) AL FLUJO DISPONIBLE EN EL RETORNO VENOSO DEL PACIENTE. UN DISPOSITIVO LLEVA UN DETECTOR (11) DE MEDICION DE UN PARAMETRO FISICO DE FUNCIONAMIENTO DE LA PROTESIS, CUYA BANDA DE TRANSMISION SE EXTIENDE MAS ALLA DE LA FRECUENCIA DE VARIACION DEL FLUJO SANGUINEO, Y COMPRENDE MEDIOS (10) DE DETERMINACION DE LA POSICION DE LA PROTESIS, UNA UNIDAD CENTRAL (15) QUE RECIBE SEÑALES DEL DETECTOR (11) Y DE LOS MEDIOS (10), DICHA UNIDAD CENTRAL PUEDE CONTROLAR MEDIOS DE ALIMENTACION (5) DEL ACCIONADOR, Y COMPRENDE UNA MEMORIA (16) EN LA QUE SE ALMACENAN VALORES NORMALES DEL PARAMETRO FISICO DE FUNCIONAMIENTO DE LA PROTESIS. EL DISPOSITIVO SEGUN LA INVENCION ESTA PARTICULARMENTE DESTINADO A LA VIGILANCIA DE FUNCIONAMIENTO DE LAS PROTESIS CARDIACAS HUMANAS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9001850A FR2658078B1 (fr) | 1990-02-09 | 1990-02-09 | Procede et dispositif de regulation de debit d'une prothese cardiaque a debit periodique. |
FR9001851A FR2658079B1 (fr) | 1990-02-09 | 1990-02-09 | Procede et dispositif de regulation d'une prothese cardiaque a debit periodique par surveillance du courant de l'actionneur. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2049546T3 true ES2049546T3 (es) | 1994-04-16 |
Family
ID=26227863
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91904121T Expired - Lifetime ES2049546T3 (es) | 1990-02-09 | 1991-02-08 | Procedimiento y dispositivo de regulacion de caudal de una protesis cardiaca de caudal periodico. |
Country Status (7)
Country | Link |
---|---|
US (1) | US5352180A (es) |
EP (1) | EP0513176B1 (es) |
JP (1) | JPH05505321A (es) |
CA (1) | CA2075472A1 (es) |
DE (1) | DE69101106T2 (es) |
ES (1) | ES2049546T3 (es) |
WO (1) | WO1991012035A1 (es) |
Families Citing this family (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0708664B1 (en) * | 1994-04-15 | 2004-01-02 | Allegheny-Singer Research Institute | Blood pump device and method for pumping blood of a patient |
US6783328B2 (en) * | 1996-09-30 | 2004-08-31 | Terumo Cardiovascular Systems Corporation | Method and apparatus for controlling fluid pumps |
EP0951302B8 (en) * | 1996-10-04 | 2006-04-19 | United States Surgical Corporation | Circulatory support system |
US5833619A (en) * | 1997-05-15 | 1998-11-10 | L. Vad Technology, Inc. | External blood pressure sensor apparatus and method |
AU741646B2 (en) * | 1997-09-30 | 2001-12-06 | L. Vad Technology, Inc. | Cardiovascular support control system |
US6610004B2 (en) | 1997-10-09 | 2003-08-26 | Orqis Medical Corporation | Implantable heart assist system and method of applying same |
US6390969B1 (en) | 1997-10-09 | 2002-05-21 | Orqis Medical Corporation | Implantable heart assist system and method of applying same |
US6387037B1 (en) | 1997-10-09 | 2002-05-14 | Orqis Medical Corporation | Implantable heart assist system and method of applying same |
US6889082B2 (en) | 1997-10-09 | 2005-05-03 | Orqis Medical Corporation | Implantable heart assist system and method of applying same |
UA56262C2 (uk) | 1997-10-09 | 2003-05-15 | Орквіс Медікел Корпорейшн | Імплантовувана система підтримки серця |
US6293901B1 (en) * | 1997-11-26 | 2001-09-25 | Vascor, Inc. | Magnetically suspended fluid pump and control system |
US5928131A (en) * | 1997-11-26 | 1999-07-27 | Vascor, Inc. | Magnetically suspended fluid pump and control system |
US6042532A (en) * | 1998-03-09 | 2000-03-28 | L. Vad Technology, Inc. | Pressure control system for cardiac assist device |
US6511412B1 (en) | 1998-09-30 | 2003-01-28 | L. Vad Technology, Inc. | Cardivascular support control system |
US6735532B2 (en) | 1998-09-30 | 2004-05-11 | L. Vad Technology, Inc. | Cardiovascular support control system |
GB2365348B (en) * | 1999-02-09 | 2003-01-15 | Vascor Inc | Fluid pump and control system |
US6540658B1 (en) | 2000-05-30 | 2003-04-01 | Abiomed, Inc. | Left-right flow control algorithm in a two chamber cardiac prosthesis |
US6527698B1 (en) | 2000-05-30 | 2003-03-04 | Abiomed, Inc. | Active left-right flow control in a two chamber cardiac prosthesis |
DE10060275A1 (de) * | 2000-12-05 | 2002-06-13 | Impella Cardiotech Ag | Verfahren zum Kalibrieren eines Drucksensors oder eines Flussensors an einer Rotationspumpe |
WO2003015609A2 (en) * | 2001-08-16 | 2003-02-27 | Apex Medical, Inc. | Physiological heart pump control |
US6817836B2 (en) * | 2002-09-10 | 2004-11-16 | Miwatec Incorporated | Methods and apparatus for controlling a continuous flow rotary blood pump |
US7468050B1 (en) | 2002-12-27 | 2008-12-23 | L. Vad Technology, Inc. | Long term ambulatory intra-aortic balloon pump |
US7172551B2 (en) * | 2004-04-12 | 2007-02-06 | Scimed Life Systems, Inc. | Cyclical pressure coronary assist pump |
US7828711B2 (en) * | 2004-08-16 | 2010-11-09 | Cardiac Pacemakers, Inc. | Method and apparatus for modulating cellular growth and regeneration using ventricular assist device |
US7775966B2 (en) | 2005-02-24 | 2010-08-17 | Ethicon Endo-Surgery, Inc. | Non-invasive pressure measurement in a fluid adjustable restrictive device |
US8016744B2 (en) | 2005-02-24 | 2011-09-13 | Ethicon Endo-Surgery, Inc. | External pressure-based gastric band adjustment system and method |
US7658196B2 (en) | 2005-02-24 | 2010-02-09 | Ethicon Endo-Surgery, Inc. | System and method for determining implanted device orientation |
US7927270B2 (en) | 2005-02-24 | 2011-04-19 | Ethicon Endo-Surgery, Inc. | External mechanical pressure sensor for gastric band pressure measurements |
US8066629B2 (en) | 2005-02-24 | 2011-11-29 | Ethicon Endo-Surgery, Inc. | Apparatus for adjustment and sensing of gastric band pressure |
US7699770B2 (en) | 2005-02-24 | 2010-04-20 | Ethicon Endo-Surgery, Inc. | Device for non-invasive measurement of fluid pressure in an adjustable restriction device |
US7775215B2 (en) | 2005-02-24 | 2010-08-17 | Ethicon Endo-Surgery, Inc. | System and method for determining implanted device positioning and obtaining pressure data |
US8657875B2 (en) * | 2005-09-26 | 2014-02-25 | Abiomed, Inc. | Method and apparatus for pumping blood |
US8870742B2 (en) | 2006-04-06 | 2014-10-28 | Ethicon Endo-Surgery, Inc. | GUI for an implantable restriction device and a data logger |
US8152710B2 (en) | 2006-04-06 | 2012-04-10 | Ethicon Endo-Surgery, Inc. | Physiological parameter analysis for an implantable restriction device and a data logger |
US8187163B2 (en) | 2007-12-10 | 2012-05-29 | Ethicon Endo-Surgery, Inc. | Methods for implanting a gastric restriction device |
US8100870B2 (en) | 2007-12-14 | 2012-01-24 | Ethicon Endo-Surgery, Inc. | Adjustable height gastric restriction devices and methods |
US8142452B2 (en) | 2007-12-27 | 2012-03-27 | Ethicon Endo-Surgery, Inc. | Controlling pressure in adjustable restriction devices |
US8377079B2 (en) | 2007-12-27 | 2013-02-19 | Ethicon Endo-Surgery, Inc. | Constant force mechanisms for regulating restriction devices |
US8337389B2 (en) | 2008-01-28 | 2012-12-25 | Ethicon Endo-Surgery, Inc. | Methods and devices for diagnosing performance of a gastric restriction system |
US8192350B2 (en) | 2008-01-28 | 2012-06-05 | Ethicon Endo-Surgery, Inc. | Methods and devices for measuring impedance in a gastric restriction system |
US8591395B2 (en) | 2008-01-28 | 2013-11-26 | Ethicon Endo-Surgery, Inc. | Gastric restriction device data handling devices and methods |
US7844342B2 (en) | 2008-02-07 | 2010-11-30 | Ethicon Endo-Surgery, Inc. | Powering implantable restriction systems using light |
US8221439B2 (en) | 2008-02-07 | 2012-07-17 | Ethicon Endo-Surgery, Inc. | Powering implantable restriction systems using kinetic motion |
US8114345B2 (en) | 2008-02-08 | 2012-02-14 | Ethicon Endo-Surgery, Inc. | System and method of sterilizing an implantable medical device |
US8057492B2 (en) | 2008-02-12 | 2011-11-15 | Ethicon Endo-Surgery, Inc. | Automatically adjusting band system with MEMS pump |
US8591532B2 (en) | 2008-02-12 | 2013-11-26 | Ethicon Endo-Sugery, Inc. | Automatically adjusting band system |
US8034065B2 (en) | 2008-02-26 | 2011-10-11 | Ethicon Endo-Surgery, Inc. | Controlling pressure in adjustable restriction devices |
US8233995B2 (en) | 2008-03-06 | 2012-07-31 | Ethicon Endo-Surgery, Inc. | System and method of aligning an implantable antenna |
US8187162B2 (en) | 2008-03-06 | 2012-05-29 | Ethicon Endo-Surgery, Inc. | Reorientation port |
US9841013B2 (en) * | 2010-02-16 | 2017-12-12 | Circulite, Inc. | Test controller for a rotary pump |
TW201217010A (en) | 2010-06-22 | 2012-05-01 | Thoratec Corp | Apparatus and method for modifying pressure-flow characteristics of a pump |
WO2011163421A1 (en) | 2010-06-22 | 2011-12-29 | Thoratec Corporation | Fluid delivery system and method for monitoring fluid delivery system |
US10342905B2 (en) | 2012-09-13 | 2019-07-09 | Circulite, Inc. | Blood flow system with variable speed control |
EP3027242B1 (en) | 2013-08-02 | 2017-04-26 | CircuLite, Inc. | Implantable system with secure remote control |
US10022268B2 (en) | 2013-12-17 | 2018-07-17 | Medical Instrument Development Laboratories, Inc. | Diaphragm-position-controlled, multi-mode ocular fluid management system and method |
US9717832B2 (en) | 2015-01-06 | 2017-08-01 | HeartWave, Inc. | Axial flow rotor with downstream bearing wash flow |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3919722A (en) * | 1973-03-06 | 1975-11-18 | Us Health | Totally implantable artificial replacement heart |
DE2355966A1 (de) * | 1973-11-09 | 1975-05-22 | Medac Klinische Spezialpraep | Pumpenanordnung, insbesondere fuer blutpumpen |
US3911897A (en) * | 1974-04-05 | 1975-10-14 | Jr Frank A Leachman | Heart assist device |
US3911898A (en) * | 1974-04-05 | 1975-10-14 | Jr Frank A Leachman | Heart assist method and device |
DE2823802C2 (de) * | 1978-05-31 | 1982-05-27 | Speidel + Keller Gmbh + Co Kg, 7455 Jungingen | Antriebsanordnung einer oszillierenden Verdrängerpumpe |
FR2458288A1 (fr) * | 1979-06-11 | 1981-01-02 | Belenger Jacques | Pompe medicale destinee a l'assistance cardiaque pulsative |
JPS60142859A (ja) * | 1983-12-29 | 1985-07-29 | 泉工医科工業株式会社 | 拍動血流量自動設定機構付ロ−ラポンプ |
US4662358A (en) * | 1984-04-17 | 1987-05-05 | Thoratec Laboratories Corporation | Electronic control system for a cardiac prosthesis |
US4756302A (en) * | 1986-11-20 | 1988-07-12 | Novacor Medical Corporation | Blood pumping system and method |
-
1991
- 1991-02-08 JP JP91504246A patent/JPH05505321A/ja active Pending
- 1991-02-08 EP EP91904121A patent/EP0513176B1/fr not_active Expired - Lifetime
- 1991-02-08 WO PCT/FR1991/000098 patent/WO1991012035A1/fr active IP Right Grant
- 1991-02-08 US US07/917,101 patent/US5352180A/en not_active Expired - Fee Related
- 1991-02-08 ES ES91904121T patent/ES2049546T3/es not_active Expired - Lifetime
- 1991-02-08 DE DE69101106T patent/DE69101106T2/de not_active Expired - Fee Related
- 1991-02-08 CA CA002075472A patent/CA2075472A1/fr not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE69101106D1 (de) | 1994-03-10 |
US5352180A (en) | 1994-10-04 |
DE69101106T2 (de) | 1994-08-11 |
CA2075472A1 (fr) | 1991-08-10 |
EP0513176B1 (fr) | 1994-01-26 |
EP0513176A1 (fr) | 1992-11-19 |
WO1991012035A1 (fr) | 1991-08-22 |
JPH05505321A (ja) | 1993-08-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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