ES2048090A1 - Procedimiento para la obtencion de nuevos antitromboticos derivados de la cumarina. - Google Patents
Procedimiento para la obtencion de nuevos antitromboticos derivados de la cumarina.Info
- Publication number
- ES2048090A1 ES2048090A1 ES9200196A ES9200196A ES2048090A1 ES 2048090 A1 ES2048090 A1 ES 2048090A1 ES 9200196 A ES9200196 A ES 9200196A ES 9200196 A ES9200196 A ES 9200196A ES 2048090 A1 ES2048090 A1 ES 2048090A1
- Authority
- ES
- Spain
- Prior art keywords
- coumarin
- procedures
- obtainment
- derived
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
- C07D311/44—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3
- C07D311/46—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3 unsubstituted in the carbocyclic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE NUEVOS ANTITROMBOTICOS DERIVADOS DE LA CUMARINA. DICHOS DERIVADOS RESPONDEN A LA FORMULA (I) EN DONDE Z Y R SE DEFINEN COMO SE INDICA EN LA DESCRIPCION. EL PROCEDIMIENTO COMPRENDE ACILAR 4-HIDROXI-CUMARINA CON UN CLORURO DE ACIDO DE FORMULA (II). LOS COMPUESTOS OBTENIDOS SON DE UTILIDAD COMO AGENTES ANTITROMBOTICOS EN LA PREVENCION Y EL TRATAMIENTO DE ENFERMEDADES TROMBOLITICAS Y CORONARIAS. OJO OJO FORMULA
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9200196A ES2048090B1 (es) | 1992-01-31 | 1992-01-31 | Procedimiento para la obtencion de nuevos antitromboticos derivados de la cumarina. |
DE69220201T DE69220201D1 (de) | 1992-01-31 | 1992-04-07 | Antithrombotika, die sich von Cumarin ableiten, und Verfahren zu ihrer Herstellung |
EP19920500036 EP0553590B1 (en) | 1992-01-31 | 1992-04-07 | Antithrombotics derived from coumarin and process for obtaining them. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9200196A ES2048090B1 (es) | 1992-01-31 | 1992-01-31 | Procedimiento para la obtencion de nuevos antitromboticos derivados de la cumarina. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2048090A1 true ES2048090A1 (es) | 1994-03-01 |
ES2048090B1 ES2048090B1 (es) | 1994-10-01 |
Family
ID=8275898
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9200196A Expired - Lifetime ES2048090B1 (es) | 1992-01-31 | 1992-01-31 | Procedimiento para la obtencion de nuevos antitromboticos derivados de la cumarina. |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0553590B1 (es) |
DE (1) | DE69220201D1 (es) |
ES (1) | ES2048090B1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1306669B1 (it) | 1999-06-14 | 2001-10-02 | Fidia Spa | Composizioni farmaceutiche comprendenti 8-cloro-3 (beta-dietilaminoetil) -4-metil-7-etossicarbonilmetossi cumarina base e |
CN105111176A (zh) * | 2015-10-16 | 2015-12-02 | 南开大学 | 3-苯氧乙酰基-4-羟基香豆素衍生物与合成方法及应用 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1252088A (es) * | 1966-12-13 | 1971-11-03 | ||
ES8106719A1 (es) * | 1980-09-11 | 1981-09-01 | Ind Farma Especial | Procedimiento para la preparacion de 3(alfa-etilbencil)-4- hidroxicumarina |
JPH0546666A (ja) * | 1991-08-16 | 1993-02-26 | Tokyo Electric Co Ltd | 情報検索装置 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2427578A (en) * | 1945-04-02 | 1947-09-16 | Wisconsin Alumni Res Found | 3-substituted 4-hydroxycoumarin and process of making it |
FR6928M (es) * | 1967-11-24 | 1969-05-05 | ||
HU177497B (en) * | 1979-08-01 | 1981-10-28 | Reanal Finomvegyszergyar | Acaricide preparation further process for preparing the active materials |
-
1992
- 1992-01-31 ES ES9200196A patent/ES2048090B1/es not_active Expired - Lifetime
- 1992-04-07 EP EP19920500036 patent/EP0553590B1/en not_active Expired - Lifetime
- 1992-04-07 DE DE69220201T patent/DE69220201D1/de not_active Expired - Lifetime
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1252088A (es) * | 1966-12-13 | 1971-11-03 | ||
ES8106719A1 (es) * | 1980-09-11 | 1981-09-01 | Ind Farma Especial | Procedimiento para la preparacion de 3(alfa-etilbencil)-4- hidroxicumarina |
JPH0546666A (ja) * | 1991-08-16 | 1993-02-26 | Tokyo Electric Co Ltd | 情報検索装置 |
Non-Patent Citations (1)
Title |
---|
BASE DE DATOS WPIL, n‘ acceso 75-54824W, 1975, Derwent Publ. Ltd., London, GB & JP-A-5046666 (TORAY INDS KK) 25.04.1975 * Resumen * * |
Also Published As
Publication number | Publication date |
---|---|
DE69220201D1 (de) | 1997-07-10 |
ES2048090B1 (es) | 1994-10-01 |
EP0553590B1 (en) | 1997-06-04 |
EP0553590A1 (en) | 1993-08-04 |
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