ES2045052T3 - Antagonistas de leucotrienos ltd4 y ltb4. - Google Patents
Antagonistas de leucotrienos ltd4 y ltb4.Info
- Publication number
- ES2045052T3 ES2045052T3 ES88115671T ES88115671T ES2045052T3 ES 2045052 T3 ES2045052 T3 ES 2045052T3 ES 88115671 T ES88115671 T ES 88115671T ES 88115671 T ES88115671 T ES 88115671T ES 2045052 T3 ES2045052 T3 ES 2045052T3
- Authority
- ES
- Spain
- Prior art keywords
- low
- ltd4
- antagonists
- alkyl
- fenilo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
- C07D327/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/02—Five-membered rings
- C07D339/06—Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
ESTA INVENCION COM''PRENDE COMPUESTOS DE LA FORMULA(I), Y SUS SALES ACEPTABLES FARMACEUTICAMENTE Y LOS ISOMEROS OPTICOS Y GEOMETRICOS DEL MISMO DONDE, X, Y Y Z SON INDEPENDIENTEMENTE O O S CON S OXIDADO OPCIONALMENTE A S = O; ALK ES UNA CADENA LINEAL O RAMIFICADA ALQUILENO O HIDROXIALQUILENO QUE CONTIENE DE 1 A 6 ATOMOS DE CARBONO; R1 ES H O BAJO ALQUILO; N ES 0 A 5; R2 ES H, BAJO ALQUILO, CICLOALQUILO - (CH2)N - CO2R1, FENILO, FENILO SUSTITUIDO CON HALO, BAJO ALQUILO O BAJO ALCOXILO; Y AR ES 5,6,7,8 - TETRAHIDRO - 1 - NAFTANILO, FENILO, O FENILO SUSTITUIDO CON BAJO ALQUILO, HIDROXILO, BAJO ALCOXILO O BAJO ALCANOILO. ESTA INVENCION ESTA EN EL CAMPO DE LOS AGENTES FARMACEUTICOS QUE ACTUAN COMO LEUCOTRIENOS D4(LTD4) ANTAGONISTAS E INCLUYE B4(LTD4) ANTAGONISTAS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/100,685 US4808729A (en) | 1987-09-24 | 1987-09-24 | Leukotriene LTD4 and LTB4 antagonists |
US07/241,265 US4923891A (en) | 1987-09-24 | 1988-09-09 | Leukotriene LTD4 and LTB4 antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2045052T3 true ES2045052T3 (es) | 1994-01-16 |
Family
ID=26797440
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88115671T Expired - Lifetime ES2045052T3 (es) | 1987-09-24 | 1988-09-23 | Antagonistas de leucotrienos ltd4 y ltb4. |
Country Status (14)
Country | Link |
---|---|
US (1) | US4923891A (es) |
EP (1) | EP0308956B1 (es) |
JP (1) | JPH01132577A (es) |
KR (1) | KR890005082A (es) |
AU (1) | AU610246B2 (es) |
DE (1) | DE3878806T2 (es) |
DK (1) | DK530888A (es) |
ES (1) | ES2045052T3 (es) |
FI (1) | FI884377A (es) |
GR (1) | GR3007858T3 (es) |
IL (1) | IL87800A (es) |
NO (1) | NO171412C (es) |
NZ (1) | NZ226318A (es) |
PT (1) | PT88580B (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5579409A (en) * | 1991-09-27 | 1996-11-26 | E. I. Du Pont De Nemours And Company | Methods for determining the exterior points of an object in a background |
EP0833664A1 (en) | 1995-06-12 | 1998-04-08 | G.D. SEARLE & CO. | Combination of a cyclooxygenase-2 inhibitor and a leukotriene b 4? receptor antagonist for the treatment of inflammations |
AU2250097A (en) * | 1996-02-13 | 1997-09-02 | G.D. Searle & Co. | Compositions comprising a cyclooxygenase-2 inhibitor and a leukotriene b4 receptor antagonist |
DE69911020T2 (de) * | 1999-10-06 | 2004-07-08 | Dainippon Ink And Chemicals, Inc. | 4-Methylen-1,3-dioxolane mit funktionellen Gruppen |
US6664287B2 (en) * | 2000-03-15 | 2003-12-16 | Bethesda Pharmaceuticals, Inc. | Antioxidants |
PL1954140T3 (pl) | 2005-11-22 | 2013-08-30 | Segetis Inc | Ketale lewulinianu glicerolu i ich zastosowanie |
CN104478844B (zh) * | 2007-10-09 | 2018-12-04 | Gf 生物化学知识产权资产有限公司 | 制备缩酮和乙缩醛的方法 |
CN102239156B (zh) | 2008-09-25 | 2014-10-15 | 塞格提斯有限公司 | 缩酮酯衍生物 |
KR101808867B1 (ko) | 2009-06-22 | 2018-01-18 | 세게티스, 인코포레이티드. | 케탈 화합물 및 이의 용도 |
KR20130102460A (ko) | 2010-05-10 | 2013-09-17 | 세게티스, 인코포레이티드. | 알킬 케탈 에스터를 함유하는 퍼스널 케어 조제물 및 제조방법 |
EP2601184B1 (en) | 2010-08-03 | 2015-12-16 | Segetis, Inc. | Methods for the manufacture of ketals |
BR112013002991A2 (pt) | 2010-08-12 | 2016-08-16 | Segetis Inc | composições de revestimento de látex incluindo carboxiéster cetal coalescentes, métodos de fabricação e usos dos mesmos |
AU2011289224B2 (en) | 2010-08-12 | 2015-04-16 | Gfbiochemicals Limited | Carboxy ester ketal removal compositions, methods of manufacture, and uses thereof |
US8632612B2 (en) | 2010-09-07 | 2014-01-21 | Segetis, Inc. | Compositions for dyeing keratin fibers |
WO2012037122A2 (en) | 2010-09-13 | 2012-03-22 | Segetis, Inc. | Fabric softener compositions and methods of manufacture thereof |
CN103154158B (zh) | 2010-10-18 | 2017-04-05 | Gf生化有限公司 | 包含羧基酯缩酮的水可稀释型涂料组合物、其生产方法和用途 |
WO2014047428A1 (en) | 2012-09-21 | 2014-03-27 | Segetis, Inc. | Cleaning, surfactant, and personal care compositions |
AU2013352172A1 (en) | 2012-11-29 | 2015-06-11 | Gfbiochemicals Limited | Carboxy ester ketals, methods of manufacture, and uses thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2839445A (en) * | 1954-01-11 | 1958-06-17 | Du Pont | Fungicidal and anti-oxidant compositions comprising 1, 3-dithiolanes |
FR4493M (es) * | 1964-07-09 | 1966-10-10 | ||
FR1445013A (fr) * | 1964-07-09 | 1966-07-08 | Thomae Gmbh Dr K | Procédé pour fabriquer des nouveaux acides dioxolano-2-carboxyliques |
FR1448340A (fr) * | 1964-07-09 | 1966-08-05 | Boehringer Sohn Ingelheim | Procédé pour fabriquer des nouveaux 1, 3-dioxolanes |
GB1427918A (en) * | 1972-05-26 | 1976-03-10 | Shell Int Research | Herbicidal glycerol acetals |
FR2577552B1 (fr) * | 1985-02-20 | 1987-09-04 | Sori Soc Rech Ind | Esters heterocycliques dissymetriques d'acides 1,4-dihydropyridine-3,5-dicarboxyliques, procede de preparation et utilisation en therapeutique |
-
1988
- 1988-09-09 US US07/241,265 patent/US4923891A/en not_active Expired - Lifetime
- 1988-09-19 IL IL87800A patent/IL87800A/xx unknown
- 1988-09-23 DK DK530888A patent/DK530888A/da not_active Application Discontinuation
- 1988-09-23 EP EP88115671A patent/EP0308956B1/en not_active Expired - Lifetime
- 1988-09-23 NZ NZ226318A patent/NZ226318A/en unknown
- 1988-09-23 NO NO884223A patent/NO171412C/no unknown
- 1988-09-23 AU AU22741/88A patent/AU610246B2/en not_active Ceased
- 1988-09-23 PT PT88580A patent/PT88580B/pt not_active IP Right Cessation
- 1988-09-23 DE DE8888115671T patent/DE3878806T2/de not_active Expired - Fee Related
- 1988-09-23 FI FI884377A patent/FI884377A/fi not_active Application Discontinuation
- 1988-09-23 ES ES88115671T patent/ES2045052T3/es not_active Expired - Lifetime
- 1988-09-24 KR KR1019880012411A patent/KR890005082A/ko not_active Application Discontinuation
- 1988-09-24 JP JP63239589A patent/JPH01132577A/ja active Pending
-
1993
- 1993-05-14 GR GR930400431T patent/GR3007858T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
NO884223D0 (no) | 1988-09-23 |
NO884223L (no) | 1989-03-28 |
AU2274188A (en) | 1989-04-06 |
FI884377A (fi) | 1989-03-25 |
PT88580A (pt) | 1988-10-01 |
IL87800A0 (en) | 1989-03-31 |
FI884377A0 (fi) | 1988-09-23 |
NZ226318A (en) | 1991-08-27 |
EP0308956A3 (en) | 1990-06-13 |
GR3007858T3 (es) | 1993-08-31 |
PT88580B (pt) | 1992-11-30 |
AU610246B2 (en) | 1991-05-16 |
NO171412C (no) | 1993-03-10 |
EP0308956A2 (en) | 1989-03-29 |
NO171412B (no) | 1992-11-30 |
US4923891A (en) | 1990-05-08 |
EP0308956B1 (en) | 1993-03-03 |
DE3878806T2 (de) | 1993-07-01 |
DK530888A (da) | 1989-03-25 |
DE3878806D1 (de) | 1993-04-08 |
KR890005082A (ko) | 1989-05-11 |
JPH01132577A (ja) | 1989-05-25 |
IL87800A (en) | 1992-12-01 |
DK530888D0 (da) | 1988-09-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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