ES2038922A1 - Procedimiento para la obtencion de nizatidina. - Google Patents
Procedimiento para la obtencion de nizatidina.Info
- Publication number
- ES2038922A1 ES2038922A1 ES919102899A ES9102899A ES2038922A1 ES 2038922 A1 ES2038922 A1 ES 2038922A1 ES 919102899 A ES919102899 A ES 919102899A ES 9102899 A ES9102899 A ES 9102899A ES 2038922 A1 ES2038922 A1 ES 2038922A1
- Authority
- ES
- Spain
- Prior art keywords
- nizatidin
- cpds
- prepn
- formula
- isothiourea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE NIZATIDINA (I) POR REACCION ENTRE UNA ISOTIOUREA (II) Y UN AGENTE ALGUILANTE (III) DONDE X ES UN GRUPO SALIENTE, PREFERENTEMENTE CL O BR. EL PROCEDIMIENTO PUEDE REALIZARSE EN UN MEDIO ACUOSO O HIDROALCOHOLICO Y EN PRESENCIA DE UNA BASE QUE PUEDE SER ORGANICA O INORGANICA. LA NIZATIDINA ES UN BLOQUEANTE DE LOS RECEPTORES HSI2 SC DE HISTAMINA Y PUEDE SER UTILIZADA EN TERAPIA COMO AGENTE ANTIULCEROSO.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9102899A ES2038922B1 (es) | 1991-12-30 | 1991-12-30 | Procedimiento para la obtencion de nizatidina. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9102899A ES2038922B1 (es) | 1991-12-30 | 1991-12-30 | Procedimiento para la obtencion de nizatidina. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2038922A1 true ES2038922A1 (es) | 1993-08-01 |
ES2038922B1 ES2038922B1 (es) | 1994-04-16 |
Family
ID=8274637
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9102899A Expired - Fee Related ES2038922B1 (es) | 1991-12-30 | 1991-12-30 | Procedimiento para la obtencion de nizatidina. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2038922B1 (es) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4375547A (en) * | 1980-10-02 | 1983-03-01 | Eli Lilly And Company | N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine |
EP0116452A2 (en) * | 1983-02-07 | 1984-08-22 | Eli Lilly And Company | Improvements in or relating to the synthesis of nizatidine |
EP0230127A1 (en) * | 1985-12-18 | 1987-07-29 | Eli Lilly And Company | Synthesis of nizatidine |
-
1991
- 1991-12-30 ES ES9102899A patent/ES2038922B1/es not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4375547A (en) * | 1980-10-02 | 1983-03-01 | Eli Lilly And Company | N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine |
EP0116452A2 (en) * | 1983-02-07 | 1984-08-22 | Eli Lilly And Company | Improvements in or relating to the synthesis of nizatidine |
EP0230127A1 (en) * | 1985-12-18 | 1987-07-29 | Eli Lilly And Company | Synthesis of nizatidine |
Also Published As
Publication number | Publication date |
---|---|
ES2038922B1 (es) | 1994-04-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC2A | Transfer of patent | ||
RD2A | Seizure of patent freed |
Effective date: 20010926 |
|
FD2A | Announcement of lapse in spain |
Effective date: 20180806 |