ES2031819T3 - Un metodo de preparar una proteina antigenica derivada de eimeriatenella. - Google Patents

Un metodo de preparar una proteina antigenica derivada de eimeriatenella.

Info

Publication number
ES2031819T3
ES2031819T3 ES198686202087T ES86202087T ES2031819T3 ES 2031819 T3 ES2031819 T3 ES 2031819T3 ES 198686202087 T ES198686202087 T ES 198686202087T ES 86202087 T ES86202087 T ES 86202087T ES 2031819 T3 ES2031819 T3 ES 2031819T3
Authority
ES
Spain
Prior art keywords
eimeria
proteins
tenella
maxima
antigen proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198686202087T
Other languages
English (en)
Inventor
Karel Z. Newman, Jr.
Thomas C. Gore
John L. Tedesco
Gary R. Petersen
Virginia M. Brothers
James G. Files
Leland S. Paul
Ray-Jen Chang
William H. Andrews
Irene Kuhn
Michael Mccaman
Stacey R. Sias
Robert M. Nordgren
Elizabeth A. Dragon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Solvay SA
Original Assignee
Solvay SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/805,301 external-priority patent/US5028694A/en
Priority claimed from US06/805,824 external-priority patent/US4874705A/en
Application filed by Solvay SA filed Critical Solvay SA
Application granted granted Critical
Publication of ES2031819T3 publication Critical patent/ES2031819T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/455—Eimeria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE PRESENTAN PROTEINAS ANTIGENAS PURIFICADAS QUE SON CAPACES DE INDUCIR EN UN POLLO UNA RESPUESTA INMUNOLOGICA QUE LE CONFIERE PROTECCION CONTRA LA INFECCION POR EIMERIA NECATRIX, EIMERIA TENELLA O EIMERIA MAXIMA. UNA PROTEINA UTIL PARA CONFERIR PROTECCION CONTRA E.TENELLA Y E.NECATRIX, SE HA DERIVADO DE LOS ESPOROCISTOS DE E.TENELLA. OTRAS PROTEINAS DERIVADAS DE MEROZOITOS DE E.MAXIMA SON UTILES PARA PROPORCIONAR PROTECCION CONTRA E.MAXIMA. TAMBIEN SE DESARROLLAN ANTICUERPOS MONOCLONALES DIRIGIDOS CONTRA LAS PROTEINAS ANTIGENAS QUE PUEDEN USARSE PARA CONFERIR A LOS POLLOS INMUNIDAD PASIVA CONTRA LA COCCIDIOSIS. ADEMAS SE PRESENTAN MOLECULAS DE ACIDO NUCLEICO QUE CODIFICAN LAS PROTEINAS ANTIGENAS ASI COMO VECTORES DE EXPRESION QUE LOS CONTIENEN. SE INDICAN METODOS PARA PRODUCIR LAS PROTEINAS O POLIPEPTIDOS ANTIGENOS QUE TIENEN SECUENCIAS DE AMINOACIDOS QUE INCLUYEN ESTAS PROTEINAS. ADEMAS SE PRESENTAN VACUNAS CON MULTICOMPONENTES QUE COMPRENDEN MEZCLAS DE ANTIGENOS O ISOTOPOS DE EIMERIA.
ES198686202087T 1985-12-03 1986-11-24 Un metodo de preparar una proteina antigenica derivada de eimeriatenella. Expired - Lifetime ES2031819T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/805,301 US5028694A (en) 1985-12-03 1985-12-03 Antigenic proteins and vaccines containing them for prevention of coccidiosis caused by eimeria Eimeria necatrix and Eimeria tenella
US06/805,824 US4874705A (en) 1985-05-16 1985-12-06 DNA encoding an antigenic protein derived from Eimeria tenella and vaccines for prevention of coccidiosis caused by Eimeria tenella
US80749785A 1985-12-11 1985-12-11
US80801385A 1985-12-11 1985-12-11

Publications (1)

Publication Number Publication Date
ES2031819T3 true ES2031819T3 (es) 1993-01-01

Family

ID=27505825

Family Applications (3)

Application Number Title Priority Date Filing Date
ES198686202087T Expired - Lifetime ES2031819T3 (es) 1985-12-03 1986-11-24 Un metodo de preparar una proteina antigenica derivada de eimeriatenella.
ES91201751T Expired - Lifetime ES2091861T3 (es) 1985-12-03 1986-11-24 Proteinas antigenicas y vacunas que las contienen para la prevencion de la coccidiosis.
ES91201752T Expired - Lifetime ES2109254T3 (es) 1985-12-03 1986-11-24 Proteinas antigenas y vacunas que las contienen para la prevencion de cocidiosis.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES91201751T Expired - Lifetime ES2091861T3 (es) 1985-12-03 1986-11-24 Proteinas antigenicas y vacunas que las contienen para la prevencion de la coccidiosis.
ES91201752T Expired - Lifetime ES2109254T3 (es) 1985-12-03 1986-11-24 Proteinas antigenas y vacunas que las contienen para la prevencion de cocidiosis.

Country Status (9)

Country Link
EP (3) EP0231537B1 (es)
JP (3) JP2548148B2 (es)
AT (3) ATE140030T1 (es)
AU (1) AU592389B2 (es)
CA (1) CA1341166C (es)
DE (3) DE3684295D1 (es)
ES (3) ES2031819T3 (es)
GR (1) GR3025209T3 (es)
IL (3) IL97566A (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4874705A (en) * 1985-05-16 1989-10-17 Solvay & Cie, S.A. DNA encoding an antigenic protein derived from Eimeria tenella and vaccines for prevention of coccidiosis caused by Eimeria tenella
CA1340520C (en) * 1984-06-05 1999-05-04 Karel Z. Newman Jr. Antigenic proteins and vaccines containing them and protective antibodies directed to them for prevention of coccidiosis caused by eimeria tenella and eimeria necatrix
US5187080A (en) * 1984-06-05 1993-02-16 Solvay & Cie S.A. DNA encoding an antigenic protein derived from Eimeria tenella and vaccines for prevention of coccidiosis caused by Eimeria tenella
US5273901A (en) * 1984-07-05 1993-12-28 Enzon Corp. Genetically engineered coccidiosis sporozoite 21.5 Kb antigen, ac-6b
US5279960A (en) * 1984-07-05 1994-01-18 Enzon Corp. 25 KD coccidial antigen of eimeria tenella
ATE145245T1 (de) * 1987-03-06 1996-11-15 Amgen Boulder Inc Polypeptide zur verwendung bei der diagnose von kokkidien-infektion und rekombinant-dns, verfahren zur herstellung derselben
NZ227595A (en) * 1988-01-15 1991-11-26 Merck & Co Inc Recombinant production of eimeria tenella antigens and their use
US5824656A (en) * 1988-01-15 1998-10-20 Merck & Co., Inc. Recombinant and native group B eimeria tenella immunogens useful as coccidiosis vaccines
NZ227597A (en) * 1988-01-15 1991-11-26 Merck & Co Inc Eimeria tenella group b immunogens and their production
ZA889230B (en) * 1988-02-12 1989-08-30 Us Agriculture Cloned genes coding for avian coccidiosis antigens which induce a cell-mediated immune response and method of producing the same
AU620366B2 (en) * 1988-02-12 1992-02-20 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Cloned genes coding for avian coccidiosis antigens which induce a cell-mediated response and method of producing the same
ZA893740B (en) * 1988-06-03 1990-02-28 Hoffmann La Roche Recombinant coccidiosis vaccines
ZA894726B (en) * 1988-06-27 1990-03-28 Akzo Nv Coccidiosis vaccine
JPH03505970A (ja) * 1988-07-05 1991-12-26 ジェネックス・コーポレーション 遺伝子工学によるコクシジウム症ワクチン
EP0444121A1 (en) * 1988-11-17 1991-09-04 FAKHRI, Omar Electro-therapy apparatus and method
NZ232372A (en) * 1989-02-10 1993-04-28 Merck & Co Inc Glycolipid-linked membrane-associated immunogens of eimeria useful in immunising poultry against coccidiosis
EP0548252A4 (en) * 1990-09-12 1995-02-15 Genex Corp Genetically engineered coccidiosis vaccine
ATE141328T1 (de) * 1991-03-14 1996-08-15 British Tech Group Usa Rekombinante vakzine gegen coccidiose
US6008342A (en) * 1991-07-12 1999-12-28 Roche Vitamins Inc. DNA encoding eimeria antigen
EP0594743B1 (en) * 1991-07-12 1999-09-22 Pfizer Inc. Continuous cell line and vaccine against avian coccidia
US5403581A (en) * 1991-07-12 1995-04-04 Hoffmann-La Roche Inc. Coccidiosis vaccines
US5861160A (en) * 1995-06-07 1999-01-19 Ambico, Inc. Isospora suis sporozoite antigen
NZ500033A (en) * 1998-10-07 2001-06-29 Akzo Nobel Nv Hydrophilic eimeria polypeptides for use as coccidiosis vaccines
US6680061B1 (en) 1998-10-07 2004-01-20 Theodorus Cornelis Schaap Coccidiosis vaccines
US7250286B2 (en) 2002-05-21 2007-07-31 Schering-Plough Corporation Methods for the in vitro culture of Sporozoea sp. and uses thereof
DE10330235A1 (de) * 2003-07-04 2005-01-20 Bayer Healthcare Ag Neues Eimeria Gen und Protein sowie deren Verwendung
US20220053799A1 (en) * 2020-06-26 2022-02-24 Zivo Bioscience, Inc. Positive latency effects on coccidiosis prevention and treatment via animal feed
PE20231653A1 (es) * 2020-06-26 2023-10-17 Zivo Bioscience Inc Cebado inmunologico para acelerar/mejorar la respuesta inmune a traves de la administracion de modulador inmunologico natural
CN113185594B (zh) * 2021-04-26 2022-12-20 中国农业科学院兰州兽医研究所 一种柔嫩艾美耳球虫的免疫抗原、抗体及其制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3147186A (en) * 1961-04-03 1964-09-01 Auburn Res Foundation Stable coccidiosis immunization
FR2408351A1 (fr) 1977-11-14 1979-06-08 Unilever Nv Procede et composition destines a la lutte contre la coccidiose chez la volaille
JPS5649323A (en) 1979-09-29 1981-05-02 Nisshin Flour Milling Co Ltd Coccidiostat
JPS5780325A (en) * 1980-09-05 1982-05-19 Nat Res Dev Coccidial disease vaccine
EP0135073A3 (en) 1983-08-19 1987-05-27 American Cyanamid Company Antigens and monoclonal antibodies reactive against merozites of eimeria spp.
EP0135712A3 (en) 1983-08-19 1987-05-27 American Cyanamid Company Antigens and monoclonal antibodies reactive against sporozoites of eimeria spp.
CA1340520C (en) * 1984-06-05 1999-05-04 Karel Z. Newman Jr. Antigenic proteins and vaccines containing them and protective antibodies directed to them for prevention of coccidiosis caused by eimeria tenella and eimeria necatrix
US4639372A (en) 1984-06-29 1987-01-27 Merck & Co., Inc. Coccidiosis vaccine
EP0190254A4 (en) * 1984-07-05 1987-03-09 Genex Corp GENE CLONE AND PROCESS FOR THE PREPARATION AND USE THEREOF.
FR2780422B1 (fr) 1998-06-26 2000-09-08 Rhodia Chimie Sa Composition thermoepaississante pour bains de couchage a base d'un copolymere possedant une temperature critique inferieure de solubilite

Also Published As

Publication number Publication date
EP0453055A3 (en) 1991-11-06
JPH10323195A (ja) 1998-12-08
DE3650540T2 (de) 1997-02-27
IL97566A0 (en) 1992-06-21
DE3684295D1 (de) 1992-04-16
EP0231537B1 (en) 1992-03-11
JPH08242864A (ja) 1996-09-24
CA1341166C (en) 2001-01-16
ES2091861T3 (es) 1996-11-16
IL80826A (en) 1992-06-21
IL97567A0 (en) 1992-06-21
IL97567A (en) 1992-08-18
IL80826A0 (en) 1987-03-31
EP0453054A3 (en) 1991-12-04
EP0453054A2 (en) 1991-10-23
DE3650540D1 (de) 1996-08-08
EP0231537A2 (en) 1987-08-12
GR3025209T3 (en) 1998-02-27
JP2907813B2 (ja) 1999-06-21
JPS62224293A (ja) 1987-10-02
AU6586986A (en) 1987-06-04
JP2837119B2 (ja) 1998-12-14
AU592389B2 (en) 1990-01-11
JP2548148B2 (ja) 1996-10-30
EP0453054B1 (en) 1996-07-03
ES2109254T3 (es) 1998-01-16
EP0453055A2 (en) 1991-10-23
DE3650645T2 (de) 1998-02-19
EP0453055B1 (en) 1997-09-03
IL97566A (en) 1992-08-18
ATE140030T1 (de) 1996-07-15
DE3650645D1 (de) 1997-10-09
ATE73494T1 (de) 1992-03-15
ATE157545T1 (de) 1997-09-15
EP0231537A3 (en) 1988-02-10

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