ES2026555T3 - Derivados del piridoinol; su aplicacion a titulo de medicamentos y las composiciones que los contienen. - Google Patents

Derivados del piridoinol; su aplicacion a titulo de medicamentos y las composiciones que los contienen.

Info

Publication number
ES2026555T3
ES2026555T3 ES198787400593T ES87400593T ES2026555T3 ES 2026555 T3 ES2026555 T3 ES 2026555T3 ES 198787400593 T ES198787400593 T ES 198787400593T ES 87400593 T ES87400593 T ES 87400593T ES 2026555 T3 ES2026555 T3 ES 2026555T3
Authority
ES
Spain
Prior art keywords
represents hydrogen
derivatives
group
piridoinol
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787400593T
Other languages
English (en)
Inventor
Emile Bisagni
Nguyen Chi Hung
Odile Pepin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Centre National de la Recherche Scientifique CNRS
Original Assignee
Sanofi SA
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA, Centre National de la Recherche Scientifique CNRS filed Critical Sanofi SA
Application granted granted Critical
Publication of ES2026555T3 publication Critical patent/ES2026555T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A LOS DERIVADOS DEL 5-H PIRIDO[4,3-B] INDOL DE FORMULA GENERAL (I) EN LA CUAL N REPRESENTA UN NUMERO ENTERO DE 2 A 4; R1 REPRESENTA HIDROGENO O UN GRUPO ALQUILO INFERIOR; R2REPRESENTA HIDROGENO, UN GRUPO HIDROXI O UN GRUPO ALQUILOXI INFERIOR; R3 Y R4 REPRESENTAN HIDROGENO, UN GRUPO ALQUILO INFERIOR O HIDROXIALQUILO; R5 PUEDE SER IDENTICO O DIFERENTE Y REPRESENTA HIDROGENO, UN GRUPO HIDROXI O UN GRUPO ALQUILO INFERIOR ASI COMO LAS FORMAS TAUTOMERAS Y LAS SALES DE ADICION FARMACEUTICAMENTE ACEPTABLES, CON LOS ACIDOS MINERALES U ORGANICOS. LA INVENCION SE REFIERE TAMBIEN AL PROCEDIMIENTO DE SU PREPARACION Y A SU APLICACION COMO MEDICAMENTOS.
ES198787400593T 1986-03-17 1987-03-17 Derivados del piridoinol; su aplicacion a titulo de medicamentos y las composiciones que los contienen. Expired - Lifetime ES2026555T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8604202A FR2595701B1 (fr) 1986-03-17 1986-03-17 Derives du pyrido-indole, leur application a titre de medicaments et les compositions les renfermant

Publications (1)

Publication Number Publication Date
ES2026555T3 true ES2026555T3 (es) 1992-05-01

Family

ID=9333475

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787400593T Expired - Lifetime ES2026555T3 (es) 1986-03-17 1987-03-17 Derivados del piridoinol; su aplicacion a titulo de medicamentos y las composiciones que los contienen.

Country Status (7)

Country Link
US (1) US4835160A (es)
EP (1) EP0239476B1 (es)
AT (1) ATE57701T1 (es)
DE (1) DE3765670D1 (es)
ES (1) ES2026555T3 (es)
FR (1) FR2595701B1 (es)
GR (1) GR3001366T3 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2661411B1 (fr) * 1990-04-25 1992-06-19 Centre Nat Rech Scient Nouveaux derives de pyridobenzoindole, leur preparation et les compositions qui les contiennent.
IL94600A0 (en) * 1989-06-06 1991-04-15 Rhone Poulenc Sante Pyridobenzoindole compounds,their preparation and compositions containing them
FR2647788B1 (fr) * 1989-06-06 1991-09-06 Centre Nat Rech Scient Nouveaux derives de pyridobenzoindole, leur preparation et les compositions qui les contiennent
FR2823975B1 (fr) * 2001-04-27 2003-05-30 Sanofi Synthelabo Nouvelle utilisation de pyridoindolone
WO2004035580A1 (en) * 2002-10-21 2004-04-29 Aprea Ab Reactivation of wild type p53 in human tumour cells by a low molecular weight compound
FR2846329B1 (fr) * 2002-10-23 2004-12-03 Sanofi Synthelabo Derives de pyridoindolone substitues en -3 par un phenyle, leur preparation et leur application en therapeutique
US7456193B2 (en) * 2002-10-23 2008-11-25 Sanofi-Aventis Pyridoindolone derivatives substituted in the 3-position by a heterocyclic group, their preparation and their application in therapeutics
FR2869316B1 (fr) * 2004-04-21 2006-06-02 Sanofi Synthelabo Derives de pyridoindolone substitues en -6, leur preparation et leur application en therapeutique.
FR2892416B1 (fr) * 2005-10-20 2008-06-27 Sanofi Aventis Sa Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique
EP2280011A1 (en) * 2009-07-28 2011-02-02 Commissariat à l'Énergie Atomique et aux Énergies Alternatives Condensed pyridine derivatives useful as potent inhibitors of the protein kinase CK2
EP3134409B1 (en) 2014-04-22 2020-02-12 Université de Montréal Compounds and use thereof in the expansion of hematopoietic stem cells and/or hematopoietic progenitor cells
WO2016138332A1 (en) * 2015-02-27 2016-09-01 The Regents Of The University Of Michigan 9h-pyrimido [4,5-b] indoles as bet bromodomain inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2327783A1 (fr) * 1975-10-16 1977-05-13 Cm Ind Application therapeutique de derives d'indolo(3,2-c)quinoleine
FR2422662A2 (fr) * 1978-04-10 1979-11-09 Anvar Dipyrido (4,3-b) (3,4-f) indoles, procede d'obtention, application therapeutique et compositions pharmaceutiques les contenant
FR2579208B1 (fr) * 1985-03-22 1987-05-07 Sanofi Sa Nouveaux derives de le 5-h pyrido (3', 4' : 4,5) pyrrolo (3,2-c) pyridine, leur procede de preparation et leur activite antitumorale

Also Published As

Publication number Publication date
FR2595701A1 (fr) 1987-09-18
ATE57701T1 (de) 1990-11-15
FR2595701B1 (fr) 1988-07-01
US4835160A (en) 1989-05-30
EP0239476B1 (fr) 1990-10-24
GR3001366T3 (en) 1992-09-11
DE3765670D1 (de) 1990-11-29
EP0239476A1 (fr) 1987-09-30

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