ES2008813A6 - Un dispositivo dosificador para liberar diltiazem. - Google Patents

Un dispositivo dosificador para liberar diltiazem.

Info

Publication number
ES2008813A6
ES2008813A6 ES8802715A ES8802715A ES2008813A6 ES 2008813 A6 ES2008813 A6 ES 2008813A6 ES 8802715 A ES8802715 A ES 8802715A ES 8802715 A ES8802715 A ES 8802715A ES 2008813 A6 ES2008813 A6 ES 2008813A6
Authority
ES
Spain
Prior art keywords
dosage form
diltiazem
delivering
delivering diltiazem
disclosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8802715A
Other languages
English (en)
Inventor
George V Guittard
Patrick S L Wong
Felix Theeuwes
Richard Cortese
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of ES2008813A6 publication Critical patent/ES2008813A6/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

UN DISPOSITIVO DOSIFICADOR PARA LIBERAR DILTIAZEM. COMPRENDE: (A) UNA PARED QUE LIMITA Y FORMA, (B) UN COMPARTIMENTO, QUE CONTIENE (C) UNA COMPOSICION DE DILTIAZEM, FORMADO POR UN 70-96% EN PESO DE UN MIEMBRO SELECCIONADO DEL GRUPO FORMADO POR DILTIAZEM Y SUS SALES FARMACEUTICAMENTE ACEPTABLES, 0,5-15% EN PESO DE UN ACIDO POLIACRILICO, 0,5-2C%, EN PESO DE POLI(OXIDO DE ETILENO) Y 0,5-20% EN PESO DE UN POLI(VINILPIRROLIDONA) Y (D) UNA COMPOSICION DE EMPUJE FORMADA POR 70-95% EN PESO DE POLI(OXIDO DE ETILENO), 1-15% EN PESO DE HIDROXIPROPILMETILCELULOSA Y (E) POR LO MENOS UN PASILLO EN LA PARED PARA LIBERAR EL DILTIAZEM DEL DISPOSITIVO. LA INVENCION ES APLICABLE PARA EL TRATAMIENTO DE ENFERMEDADES CARDIOVASCULARES.
ES8802715A 1988-06-02 1988-09-02 Un dispositivo dosificador para liberar diltiazem. Expired ES2008813A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/201,519 US4859470A (en) 1988-06-02 1988-06-02 Dosage form for delivering diltiazem

Publications (1)

Publication Number Publication Date
ES2008813A6 true ES2008813A6 (es) 1989-08-01

Family

ID=22746162

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8802715A Expired ES2008813A6 (es) 1988-06-02 1988-09-02 Un dispositivo dosificador para liberar diltiazem.

Country Status (25)

Country Link
US (1) US4859470A (es)
JP (1) JP2590226B2 (es)
KR (1) KR960006062B1 (es)
AR (1) AR241635A1 (es)
AT (1) AT394311B (es)
AU (1) AU612398B2 (es)
BE (1) BE1001935A3 (es)
CA (1) CA1311687C (es)
CH (1) CH675208A5 (es)
DE (1) DE3829941C2 (es)
DK (1) DK175396B1 (es)
ES (1) ES2008813A6 (es)
FI (1) FI92553C (es)
FR (1) FR2632306B1 (es)
GB (1) GB2219205B (es)
GR (1) GR1000197B (es)
IE (1) IE61861B1 (es)
IT (1) IT1223799B (es)
LU (1) LU87327A1 (es)
MX (1) MX174157B (es)
NL (1) NL194747C (es)
NO (1) NO174766C (es)
PT (1) PT88405B (es)
SE (1) SE503508C2 (es)
ZA (1) ZA886436B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5030452A (en) * 1989-01-12 1991-07-09 Pfizer Inc. Dispensing devices powered by lyotropic liquid crystals
IL92966A (en) * 1989-01-12 1995-07-31 Pfizer Hydrogel-operated release devices
US5108756A (en) * 1989-01-12 1992-04-28 Pfizer Inc. Dispensing devices powered by lyotropic liquid crystals
US5112614A (en) * 1989-09-14 1992-05-12 Alza Corporation Implantable delivery dispenser
US5208037A (en) * 1991-04-22 1993-05-04 Alza Corporation Dosage forms comprising polymers comprising different molecular weights
US6283951B1 (en) * 1996-10-11 2001-09-04 Transvascular, Inc. Systems and methods for delivering drugs to selected locations within the body
US6524620B2 (en) 1998-07-20 2003-02-25 Andrx Pharmaceuticals, Inc. Diltiazem controlled release formulation and method of manufacture
US6562375B1 (en) 1999-08-04 2003-05-13 Yamanouchi Pharmaceuticals, Co., Ltd. Stable pharmaceutical composition for oral use
AU769807B2 (en) * 1999-08-04 2004-02-05 Astellas Pharma Inc. Stable medicinal compositions for oral use
US20060153914A1 (en) * 1999-12-10 2006-07-13 Biovail Laboratories International S.R.L. Chronotherapeutic diltiazem formulations and the administration thereof
US7108866B1 (en) 1999-12-10 2006-09-19 Biovall Laboratories International Srl Chronotherapeutic diltiazem formulations and the administration thereof
US6753011B2 (en) 2000-01-14 2004-06-22 Osmotica Corp Combined diffusion/osmotic pumping drug delivery system
US6352721B1 (en) * 2000-01-14 2002-03-05 Osmotica Corp. Combined diffusion/osmotic pumping drug delivery system
AR040682A1 (es) * 2002-07-25 2005-04-13 Pharmacia Corp Forma de dosificacion una vez al dia de pramipexol
SG164375A1 (en) 2004-08-13 2010-09-29 Boehringer Ingelheim Int Extended release pellet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof
EP2135602A1 (en) 2004-08-13 2009-12-23 Boehringer Ingelheim International GmbH Extended release tablet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3845770A (en) * 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) * 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
GB1478759A (en) * 1974-11-18 1977-07-06 Alza Corp Process for forming outlet passageways in pills using a laser
US4063064A (en) * 1976-02-23 1977-12-13 Coherent Radiation Apparatus for tracking moving workpiece by a laser beam
US4111202A (en) * 1976-11-22 1978-09-05 Alza Corporation Osmotic system for the controlled and delivery of agent over time
US4160452A (en) * 1977-04-07 1979-07-10 Alza Corporation Osmotic system having laminated wall comprising semipermeable lamina and microporous lamina
US4285987A (en) * 1978-10-23 1981-08-25 Alza Corporation Process for manufacturing device with dispersion zone
US4200098A (en) * 1978-10-23 1980-04-29 Alza Corporation Osmotic system with distribution zone for dispensing beneficial agent
US4235236A (en) * 1979-02-12 1980-11-25 Alza Corporation Device for dispensing drug by combined diffusional and osmotic operations
IT1153487B (it) * 1982-04-15 1987-01-14 Prophin Lab Spa Prodotti farmaceutici in forma-ritardo e procedimento per ottenerli
NZ206600A (en) * 1983-05-11 1987-01-23 Alza Corp Osmotic drug delivery device
US4783337A (en) * 1983-05-11 1988-11-08 Alza Corporation Osmotic system comprising plurality of members for dispensing drug
IE56999B1 (en) * 1983-12-22 1992-03-11 Elan Corp Plc Pharmaceutical formulation
IT1206166B (it) * 1984-07-26 1989-04-14 Sigma Tau Ind Farmaceuti Dispositivo per rilasciare una sostanza in un fluido di dissoluzione con cinetica di ordine zero e procedimento per la sua preparazione
US4624847A (en) * 1985-04-22 1986-11-25 Alza Corporation Drug delivery device for programmed delivery of beneficial drug
DE3681348D1 (de) * 1985-06-11 1991-10-17 Teijin Ltd Oral-arzneizubereitung mit retardwirkung.
US4753802A (en) * 1986-03-19 1988-06-28 Alza Corporation Verapamil dosage form
ATE75394T1 (de) * 1986-11-14 1992-05-15 Ciba Geigy Ag Orales osmotisches system fuer metoprolol mit verbesserten formulierungseigenschaften.

Also Published As

Publication number Publication date
FI884057A0 (fi) 1988-09-02
AR241635A1 (es) 1992-10-30
IT8867791A0 (it) 1988-09-02
NO883838L (no) 1989-12-04
KR960006062B1 (ko) 1996-05-08
DK485688A (da) 1989-12-03
ZA886436B (en) 1989-05-30
NO174766B (no) 1994-03-28
BE1001935A3 (fr) 1990-04-17
PT88405A (pt) 1990-06-29
JPH01313432A (ja) 1989-12-18
IT1223799B (it) 1990-09-29
NL194747B (nl) 2002-10-01
AT394311B (de) 1992-03-10
FR2632306B1 (fr) 1990-11-16
PT88405B (pt) 1995-07-18
FI884057A (fi) 1989-12-03
GB8820461D0 (en) 1988-09-28
SE8803085D0 (sv) 1988-09-02
LU87327A1 (fr) 1989-03-08
AU2152788A (en) 1989-12-07
DE3829941C2 (de) 1997-07-03
SE503508C2 (sv) 1996-06-24
GB2219205A (en) 1989-12-06
GR880100574A (en) 1990-05-11
IE882642L (en) 1989-12-02
DK175396B1 (da) 2004-09-27
DK485688D0 (da) 1988-09-01
NL8802181A (nl) 1990-01-02
FR2632306A1 (fr) 1989-12-08
JP2590226B2 (ja) 1997-03-12
NO883838D0 (no) 1988-08-29
KR900000076A (ko) 1990-01-30
US4859470A (en) 1989-08-22
SE8803085L (sv) 1989-12-03
ATA214588A (de) 1991-09-15
NO174766C (no) 1994-07-06
GR1000197B (el) 1992-03-20
DE3829941A1 (de) 1989-12-14
MX174157B (es) 1994-04-25
FI92553C (fi) 1994-12-12
CH675208A5 (es) 1990-09-14
AU612398B2 (en) 1991-07-11
CA1311687C (en) 1992-12-22
NL194747C (nl) 2003-02-04
IE61861B1 (en) 1994-11-30
FI92553B (fi) 1994-08-31
GB2219205B (en) 1992-07-15

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2008-09-02

FD1A Patent lapsed

Effective date: 20080903