ES2008204A6 - Metodos para producir cuerpos de inclusion polihedrica de composicion mezclada (pib),para coinfectar insectos huespedes y para producir proteinas heterologas en insectos. - Google Patents
Metodos para producir cuerpos de inclusion polihedrica de composicion mezclada (pib),para coinfectar insectos huespedes y para producir proteinas heterologas en insectos.Info
- Publication number
- ES2008204A6 ES2008204A6 ES878702586A ES8702586A ES2008204A6 ES 2008204 A6 ES2008204 A6 ES 2008204A6 ES 878702586 A ES878702586 A ES 878702586A ES 8702586 A ES8702586 A ES 8702586A ES 2008204 A6 ES2008204 A6 ES 2008204A6
- Authority
- ES
- Spain
- Prior art keywords
- pib
- baculoviruses
- heterologous protein
- producing
- mixed composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
METODO PARA PRODUCIR CUERPOS DE INCLUSION POLIHEDRICA DE COMPOSICION MEZCLADA (PIB), PARA COINFECTAR INSECTOS HUESPEDES Y PARA PRODUCIR HETEROLOGAS EN INSECTOS. LOS PIB, CONTENIENDO UNA MEZCLA DE NUCLEOCAPSIDOS DE POR LO MENOS DOS BACULOVIRUS GENETICAMENTE DISTINTOS, SE OBTIENEN INFECTANDO UN CULTIVO CELULAR DE CELULAS QUE TOLERAN EL BACULOVIRUS CON LA FORMA NO OCLUIDA DE LOS BACULOVIRUS GENETICAMENTE DISTINTOS Y CULTIVANDO LAS CELULAS INFECTADAS, O BIEN INFECTANDO UN INSECTO CON LOS BACULOVIRUS GENETICAMENTE DISTINTOS. LA COINFECCION DEL INSECTO HUESPED SE EFECTUA PERMITIENDO QUE EL INSECTO INGIERA UNA CANTIDAD EFICAZ DEL PIB LO QUE ORIGINA UNA INFECCION VIRICA MIXTA EN EL MISMO. DESARROLLANDO EL INSECTO O CELULAS EN CONDICIONES ADECUADAS QUE PERMITAN LA REPLICACION VIRICA, SE CONSIGUE LA PRODUCCION DE PROTEINAS HETEROLOGAS CODIFICADAS POR EL GEN HETEROLOGO PRESENTE EN UNO DE LOS BACULOVIRUS. APLICACION EN INGENIERIA GENETICA PARA LA SINTESIS DE PROTEINAS HETEROLOGAS EN CELULAS DE INSECTOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US90572986A | 1986-09-09 | 1986-09-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2008204A6 true ES2008204A6 (es) | 1989-07-16 |
Family
ID=25421367
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES878702586A Expired ES2008204A6 (es) | 1986-09-09 | 1987-09-08 | Metodos para producir cuerpos de inclusion polihedrica de composicion mezclada (pib),para coinfectar insectos huespedes y para producir proteinas heterologas en insectos. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0323974B1 (es) |
JP (1) | JPH02500402A (es) |
AU (1) | AU601232B2 (es) |
CA (1) | CA1330426C (es) |
DE (1) | DE3788352T2 (es) |
ES (1) | ES2008204A6 (es) |
WO (1) | WO1988002030A1 (es) |
ZA (1) | ZA876696B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8810808D0 (en) * | 1988-05-06 | 1988-06-08 | Wellcome Found | Vectors |
JP2511494B2 (ja) * | 1988-05-12 | 1996-06-26 | 善治 松浦 | 日本脳炎ウイルス表面抗原蛋白質の製造法 |
WO1990001556A1 (en) * | 1988-08-05 | 1990-02-22 | Mount Sinai School Of Medicine Of The City University Of New York | In vivo infection of live insects with a recombinant baculovirus |
AU4647889A (en) * | 1988-11-18 | 1990-06-12 | Cetus Corporation | Insect signal peptide mediated secretion of recombinant proteins |
US5272063A (en) * | 1988-11-22 | 1993-12-21 | Syntex (U.S.A.) Inc. | Process of making human nerve growth factor |
US5145775A (en) * | 1989-02-28 | 1992-09-08 | Research Association For Biotechnology Of Agricultural Chemicals | Polyhedrin gene and genetic engineering thereof |
GB9219562D0 (en) | 1992-03-11 | 1992-10-28 | Prendergast Kennet F | Anti-viral peptides |
US6130074A (en) * | 1992-06-01 | 2000-10-10 | American Cyanamid Company Five Giralda Farms | Recombinant insect virus with reduced capacity for host-to-host transmission in the environment and methods to produce said virus |
HU218849B (hu) * | 1992-06-01 | 2000-12-28 | American Cyanamid Co. | Gazdaszervezetről gazdaszervezetre a környezetben csökkent terjedési képességgel rendelkező rekombináns bakulovirus és eljárás előállítására |
DK0732340T3 (da) * | 1995-03-14 | 2004-10-25 | Akzo Nobel Nv | Ekspression af porcine reproduktions- og respirationssyndromviruspolypeptider i den samme celle |
MX358863B (es) | 2013-09-23 | 2018-09-05 | Univ Navarra Publica | Produccion de cuerpos de inclusion de virus que incluyen viriones que contienen genomas de diferentes especies de baculovirus que pueden usarse para combatir plagas de insectos. |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK518384A (da) * | 1984-01-31 | 1985-07-01 | Idaho Res Found | Vektor til fremstilling af et gen-produkt i insektceller, fremgangsmaade til dens fremstilling samt dens anvendelse |
EP0222412B1 (en) * | 1985-11-14 | 1992-11-19 | Daiichi Pharmaceutical Co., Ltd. | Method of producing peptides |
EP0260090A3 (en) * | 1986-09-08 | 1988-07-27 | David H.L. Bishop | Expression of hepatitis b viral antigens from recombinant baculovirus vectors |
-
1987
- 1987-09-08 ES ES878702586A patent/ES2008204A6/es not_active Expired
- 1987-09-08 ZA ZA876696A patent/ZA876696B/xx unknown
- 1987-09-09 CA CA000546371A patent/CA1330426C/en not_active Expired - Fee Related
- 1987-09-09 WO PCT/US1987/002315 patent/WO1988002030A1/en active IP Right Grant
- 1987-09-09 JP JP62505806A patent/JPH02500402A/ja active Pending
- 1987-09-09 DE DE87906361T patent/DE3788352T2/de not_active Expired - Fee Related
- 1987-09-09 AU AU80323/87A patent/AU601232B2/en not_active Withdrawn - After Issue
- 1987-09-09 EP EP87906361A patent/EP0323974B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU601232B2 (en) | 1990-09-06 |
WO1988002030A1 (en) | 1988-03-24 |
EP0323974B1 (en) | 1993-12-01 |
ZA876696B (en) | 1988-05-25 |
AU8032387A (en) | 1988-04-07 |
EP0323974A1 (en) | 1989-07-19 |
EP0323974A4 (en) | 1990-02-21 |
DE3788352T2 (de) | 1994-03-17 |
CA1330426C (en) | 1994-06-28 |
JPH02500402A (ja) | 1990-02-15 |
DE3788352D1 (de) | 1994-01-13 |
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